Sorex fumeus (smoky shrew): 130044159
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Entry
130044159 CDS
T10594
Symbol
ARHGEF1
Name
(RefSeq) rho guanine nucleotide exchange factor 1 isoform X1
KO
K12330
Rho guanine nucleotide exchange factor 1
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04270
Vascular smooth muscle contraction
sfum04611
Platelet activation
sfum04810
Regulation of actin cytoskeleton
sfum04928
Parathyroid hormone synthesis, secretion and action
sfum05135
Yersinia infection
sfum05163
Human cytomegalovirus infection
sfum05200
Pathways in cancer
sfum05205
Proteoglycans in cancer
sfum05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
130044159 (ARHGEF1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
130044159 (ARHGEF1)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
130044159 (ARHGEF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
130044159 (ARHGEF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
130044159 (ARHGEF1)
05205 Proteoglycans in cancer
130044159 (ARHGEF1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
130044159 (ARHGEF1)
09171 Infectious disease: bacterial
05135 Yersinia infection
130044159 (ARHGEF1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
130044159 (ARHGEF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
sfum04131
]
130044159 (ARHGEF1)
Membrane trafficking [BR:
sfum04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
130044159 (ARHGEF1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PH_13
SOS1_NGEF_PH
AbiJ_NTD3
SET_assoc
Motif
Other DBs
NCBI-GeneID:
130044159
NCBI-ProteinID:
XP_055992734
LinkDB
All DBs
Position
Unknown
AA seq
944 aa
AA seq
DB search
MEGEDCARGVAPGAPRPGPVPISIIGAEDEDFENELETNTEAHNSQFQSLEEVKRRPAHL
MALLHHVALQFEPGPLLCCLHADMLASLGPKEARKAFLDFYHSFLEKTAVLRVPVPPSVA
FELDRTRPDLLSEDSQRQSVQEVVQSQQETVGRQLDDFRSKRLMGMTPWEQELGQLEAWV
GRDRATFEARERHVAERLLSHLEEMQHTVSADEEKSAAVVNAISVYMRHLGVRTKSCDKK
SGRNFFRKKVMGNRRSDEPTKTKKGLSSFLEAARWNRGEPQAPDFRHLRADADAEKPGFA
ERKGGLGLPSRDRNTGGSGQDPPGVSLLPPSGDCPDRDAGVDTPPEMGELSLQGPASLEP
PAPLENAEEGADSESFGAKGRGGGRSRSDVDMDPSSATAALGPARRATPEPGDEGEPGRP
AQDPEPEEPPGWRELVPADTLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFYQPM
ADGGFFSLEELQNIFPSLDELIEVHSLFLNCLMKRRQDSGHLIEEIGDVLLARFDGTEGS
WFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLT
KYPLLLQSIGQNTEEPKEREKVERAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSH
LRQSSDPMLSEFKNLDITKKKLIHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLL
LKSHSRTLTATPDGKTMLRPVLRLTSAMTRDVATDHKAFYVIFTWDQEAQIYELVAQTVS
ERKNWCALITETAGSLKVPAPASRPKPRPSPSSIREPLLSSAENGSVSREAPPADGRMEK
IVSALLPFCRPGPEGQLSAKALRKVLSLKRLMAEEDNGAGPPREGDGGPEGGPPTSTRNQ
EIQEDLLDLEETIKQIEEMEEEFCRLRPVLFQLRDITATPPGCT
NT seq
2835 nt
NT seq
+upstream
nt +downstream
nt
atggagggagaggactgcgcccgaggggtggcccccggggctccccggcctggcccggtg
cccattagcatcatcggggccgaggatgaggattttgagaatgagctggagacgaacacg
gaggcgcacaacagccagttccagagcctggaggaggtgaagcggcgcccggcgcacctc
atggccctgctgcaccatgtggccctgcagttcgagccgggacccctgctctgctgccta
catgcggacatgctggcctcgctgggccccaaggaggccaggaaggccttcctcgacttc
taccacagcttcctggagaagactgcggtcctgcgggtgccggtcccaccctctgtcgcc
tttgaacttgaccgcacgcggcctgacctcctctcggaggacagccagaggcagtcggtg
caggaggtggtgcagagccagcaggagaccgtggggcggcagctggacgacttccgctcc
aagcggctcatgggcatgacgccctgggagcaggagctgggccagctagaggcctgggtg
ggccgtgaccgcgccaccttcgaggcccgggagcggcacgtggcggagcggctgctgtcc
cacctggaggagatgcaacacaccgtctctgcggatgaggagaaaagtgccgctgtggtc
aatgccatcagtgtctacatgcgccacctcggggtgcggaccaagagctgtgacaagaag
tcggggaggaacttcttccggaaaaaggtgatggggaaccggcggtcagatgaaccgacc
aagaccaagaagggactgagcagcttcctggaggctgcccgctggaaccggggggaaccc
caggccccagattttcgacacctcagagccgatgctgatgctgagaagccaggctttgcg
gaacggaagggaggcctggggctaccttcccgggaccggaataccgggggctccgggcag
gacccccctggagtctctctgctcccaccgtctggggactgtccagaccgggatgcaggt
gtggacactcctccggagatgggggaactgtcactgcagggccccgccagcctggagccc
cccgcccccctggagaacgcagaagaaggcgctgactcagagagcttcggggcgaagggc
cggggtgggggccgctcccggagcgacgtggacatggaccccagctctgccacggccgca
ctaggccctgcccgacgagccacccccgagcctggggacgagggggagccggggcggcct
gcacaggaccctgagcccgaggagccccctggctggcgggagctggtccccgcggacacc
ctgcacagcctgcccaagagccaggtgaagcggcaggaggtgatcagcgagctgctggtg
acggaggcagcccacgttcgcatgctccgggtgctgcacgatctcttctaccagcccatg
gccgatggcggcttcttctcactggaggagctgcagaacatcttccccagcctggacgag
ctcatcgaggtgcactccctgttcctcaattgcctgatgaagcggaggcaggacagtggc
cacctcatcgaggagatcggagacgtgctgctggcccggttcgatgggaccgagggctcc
tggttccagaaaatctcctcccgcttctgcagccgccagtcatttgccttagagcagctt
aaagccaaacagcgcaaggagccgcggttctgtgccttcgtgcaggaggcggagagccgg
cctcggtgccgccgcctgcagctgaaagacatgattcccacggagatgcagcggctcacc
aagtacccgctgctgctgcagagcattgggcagaacacagaggagcccaaggaacgggag
aaagtggagcgggccgccgagtgttgccgggaaatcctgcaccacgtcaatcaggctgtg
cgcgacatggaggacctgctgcggctcaaggattatcagcgacgcctggacttgtcccac
ttgcggcagagcagtgaccctatgctgagcgagttcaagaacctggacatcacaaagaag
aagctcatccacgaaggcccgctgacgtggcgggtgaccaaggacaaggctgtggaggtg
cacgtgctgctgctggatgacctcctcctgctgctgcagcgccaggacgagcggctgctg
ctcaagtcgcacagccgcacactgacggccacgcccgacggcaagaccatgctgcggccc
gtgctgcgactgacgtcagccatgacgcgcgacgtggccacggatcacaaagccttctat
gtcattttcacctgggaccaggaagcacagatctacgagctggtggcacagactgtgtct
gagcgcaagaattggtgcgccctcatcacggagaccgctggatccctgaaggtccctgcc
cccgcctcccgccccaagccccggcccagcccgagcagcattcgtgaacccctgctcagc
agtgctgagaatggcagtgttagccgggaggcacctcccgctgacggccggatggagaag
attgtcagtgccctcctgcccttctgcagacctggccctgagggccagctctctgccaag
gcgcttcgcaaagtgctgtccctgaaacggctcatggcagaggaagacaacggggcaggt
cctcctcgagaaggggatgggggcccagagggcggccccccaacatccacccgcaaccag
gagattcaggaggacctcctggacctggaggagaccatcaaacagattgaggagatggag
gaggagttttgtcgcctgcgaccggtcctatttcagctcagggacatcactgccaccccg
cctggctgcacttga
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