KEGG   Sorex fumeus (smoky shrew): 130045178
Entry
130045178         CDS       T10594                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum01521  EGFR tyrosine kinase inhibitor resistance
sfum01522  Endocrine resistance
sfum04010  MAPK signaling pathway
sfum04012  ErbB signaling pathway
sfum04014  Ras signaling pathway
sfum04062  Chemokine signaling pathway
sfum04068  FoxO signaling pathway
sfum04072  Phospholipase D signaling pathway
sfum04150  mTOR signaling pathway
sfum04151  PI3K-Akt signaling pathway
sfum04380  Osteoclast differentiation
sfum04510  Focal adhesion
sfum04540  Gap junction
sfum04550  Signaling pathways regulating pluripotency of stem cells
sfum04630  JAK-STAT signaling pathway
sfum04650  Natural killer cell mediated cytotoxicity
sfum04660  T cell receptor signaling pathway
sfum04662  B cell receptor signaling pathway
sfum04664  Fc epsilon RI signaling pathway
sfum04714  Thermogenesis
sfum04722  Neurotrophin signaling pathway
sfum04910  Insulin signaling pathway
sfum04912  GnRH signaling pathway
sfum04915  Estrogen signaling pathway
sfum04917  Prolactin signaling pathway
sfum04926  Relaxin signaling pathway
sfum04935  Growth hormone synthesis, secretion and action
sfum05034  Alcoholism
sfum05160  Hepatitis C
sfum05161  Hepatitis B
sfum05163  Human cytomegalovirus infection
sfum05165  Human papillomavirus infection
sfum05200  Pathways in cancer
sfum05203  Viral carcinogenesis
sfum05205  Proteoglycans in cancer
sfum05206  MicroRNAs in cancer
sfum05207  Chemical carcinogenesis - receptor activation
sfum05208  Chemical carcinogenesis - reactive oxygen species
sfum05210  Colorectal cancer
sfum05211  Renal cell carcinoma
sfum05213  Endometrial cancer
sfum05214  Glioma
sfum05215  Prostate cancer
sfum05220  Chronic myeloid leukemia
sfum05221  Acute myeloid leukemia
sfum05223  Non-small cell lung cancer
sfum05224  Breast cancer
sfum05225  Hepatocellular carcinoma
sfum05226  Gastric cancer
sfum05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    130045178 (GRB2)
   04012 ErbB signaling pathway
    130045178 (GRB2)
   04014 Ras signaling pathway
    130045178 (GRB2)
   04630 JAK-STAT signaling pathway
    130045178 (GRB2)
   04068 FoxO signaling pathway
    130045178 (GRB2)
   04072 Phospholipase D signaling pathway
    130045178 (GRB2)
   04151 PI3K-Akt signaling pathway
    130045178 (GRB2)
   04150 mTOR signaling pathway
    130045178 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    130045178 (GRB2)
   04540 Gap junction
    130045178 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    130045178 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    130045178 (GRB2)
   04660 T cell receptor signaling pathway
    130045178 (GRB2)
   04662 B cell receptor signaling pathway
    130045178 (GRB2)
   04664 Fc epsilon RI signaling pathway
    130045178 (GRB2)
   04062 Chemokine signaling pathway
    130045178 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    130045178 (GRB2)
   04912 GnRH signaling pathway
    130045178 (GRB2)
   04915 Estrogen signaling pathway
    130045178 (GRB2)
   04917 Prolactin signaling pathway
    130045178 (GRB2)
   04926 Relaxin signaling pathway
    130045178 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    130045178 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    130045178 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    130045178 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    130045178 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    130045178 (GRB2)
   05206 MicroRNAs in cancer
    130045178 (GRB2)
   05205 Proteoglycans in cancer
    130045178 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    130045178 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    130045178 (GRB2)
   05203 Viral carcinogenesis
    130045178 (GRB2)
   05231 Choline metabolism in cancer
    130045178 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    130045178 (GRB2)
   05225 Hepatocellular carcinoma
    130045178 (GRB2)
   05226 Gastric cancer
    130045178 (GRB2)
   05214 Glioma
    130045178 (GRB2)
   05221 Acute myeloid leukemia
    130045178 (GRB2)
   05220 Chronic myeloid leukemia
    130045178 (GRB2)
   05211 Renal cell carcinoma
    130045178 (GRB2)
   05215 Prostate cancer
    130045178 (GRB2)
   05213 Endometrial cancer
    130045178 (GRB2)
   05224 Breast cancer
    130045178 (GRB2)
   05223 Non-small cell lung cancer
    130045178 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    130045178 (GRB2)
   05160 Hepatitis C
    130045178 (GRB2)
   05163 Human cytomegalovirus infection
    130045178 (GRB2)
   05165 Human papillomavirus infection
    130045178 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    130045178 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    130045178 (GRB2)
   01522 Endocrine resistance
    130045178 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sfum04131]
    130045178 (GRB2)
Membrane trafficking [BR:sfum04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    130045178 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 DUF7145 SH2_2 DUF5093 hSH3 SH3_4 DUF7063
Other DBs
NCBI-GeneID: 130045178
NCBI-ProteinID: XP_055993857
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVSRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaagtatgacttcaaagccacggcggacgacgagctgagcttcaaa
cgcggggacatcctcaaggtgttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatggcaaagacggcttcattcccaagaactacatagagatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggccgaagaaatgctcagcaaacagcggcacgac
ggggccttcctcatccgggagagcgagagtgctcccggggacttctctctctccgtcaag
ttcggcaacgatgtgcagcacttcaaggttctccgggacggggccggcaagtacttcctg
tgggtggtgaagttcaactccctgaacgagctggtggattaccacagatccacatccgtg
tcccggaaccagcagatcttcctccgggacatcgagcaggtgcctcagcaacccacgtac
gtgcaggcgctctttgattttgacccccaggaggacggcgagctgggctttcgccgggga
gactttatccacgtcatggataactcggaccccaactggtggaagggggcttgccacggg
cagacgggcatgttcccccgcaattacgtcacccccgtgagcagaaacgtttag

DBGET integrated database retrieval system