Serratia fonticola DSM 4576: WN53_05555
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Entry
WN53_05555 CDS
T04030
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sfw
Serratia fonticola DSM 4576
Pathway
sfw00270
Cysteine and methionine metabolism
sfw00450
Selenocompound metabolism
sfw00670
One carbon pool by folate
sfw01100
Metabolic pathways
sfw01110
Biosynthesis of secondary metabolites
sfw01230
Biosynthesis of amino acids
sfw04981
Folate transport and metabolism
Module
sfw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sfw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
WN53_05555 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
WN53_05555 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
WN53_05555 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
WN53_05555 (metH)
04980 Cobalamin transport and metabolism
WN53_05555 (metH)
Enzymes [BR:
sfw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
WN53_05555 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AKG68635
UniProt:
A0A0F7D1A3
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Position
complement(1268613..1272293)
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AA seq
1226 aa
AA seq
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MINRVEQLRQQLSQRILVLDGGMGTMIQSYRLEEADYRGERFADWQSDLKGNNDLLVLSK
PEVITAIHNGYLEAGADILETNTFNSTTIAMADYHMESLSAEINYQAALLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNVSFDQLVEAYRESTRALVEGGADLIMI
ETIFDTLNAKAAAFAVETEFEALGVTLPIMISGTITDASGRTLSGQTTEAFYNSLRHVKP
LTFGLNCALGPDELRQYVAELSRISESYVTAHPNAGLPNAFGEYDLDAEEMAKQVGEWAH
AGFLNIIGGCCGTTPAHIAAMAKAVEGVPPRQLPELPVACRLSGLEPLNIDAKSLFVNVG
ERTNVTGSARFKRLIKEEKYNEALAVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWSVIEKGLKCIQGKGIVNSISMKEGEEAFIHHAKLVRRYGAAV
VVMAFDEVGQADTRQRKFEICRRAYQILTERVGFPPEDIIFDPNIFAVATGIEEHNNYAV
DFIEACADIKTHLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYHAIRNGMDMGIVNAG
QLAIYDDLSTELREAVEDVVLNRRQDGTERLLELAEKYRGSKDNEVAVQQAEWRGWPVVK
RLEYSLVKGITEFIELDTEEARQQADRPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKS
ARVMKQAVAYLEPYIEASKQKGTTAGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLG
VMVPTDKILKTAREQNVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKAH
TAVKIEQNYSGSTTYVQNASRTVGVVAALLSDTQRDEFVARTRKEYETVRIQHGRKKPRT
PPVSLQQARDNAMVLDWENYQPPVPNKLGVFPVEASINTLRHYIDWTPFFMTWSLAGKYP
RILEDEVVGEEAKRLFQDANEMLDMLAATGTLNPRGVYGLFPANRVGDDVEVYRDESREE
VLVVSRHLRQQTEKTDFPNYCLADFVAPKSSGKADYFGAFAVTGGLEEDALAAAYDAKHD
DYNKIMVKALSDRLAEAFAEYLHEQVRKLHWGFAADENLSNEELIRENYQGIRPAPGYPA
CPEHTEKAEIWQLLDVNRHTGMELTESFAMWPGAAVSGWYFSHPQSKYFAVAQIQRDQVE
DYAQRKGMKISDVERWLAPNLGYDAD
NT seq
3681 nt
NT seq
+upstream
nt +downstream
nt
gtgataaatcgagtggaacaactgcgtcagcagctatcgcagcgtattttagtgttggac
ggcggtatgggcaccatgatccagagctatcggctggaggaggcagactaccgcggtgag
cgttttgccgattggcaaagcgatctgaaaggcaataacgacctgctggtgttaagcaag
ccggaggtgatcactgcgatccacaacggttacctggaggcgggggccgacatcctcgaa
accaataccttcaactcgaccactatcgcgatggccgactaccatatggagtcgctgtcc
gccgaaattaactaccaggccgctttgctggctcgtgcttgtgctgatgaatggacggcg
cgcaccccggaaaagccgcgctacgtcgctggtgtactgggcccaaccaaccgtaccgcc
tctatctcccctgacgttaacgatccggccttccgtaatgtctcttttgaccagttggta
gaggcctaccgcgaatcaacccgcgcgctggtggaagggggggccgatctgatcatgatc
gaaaccatcttcgataccctgaatgccaaagcggcggcctttgcggtcgaaaccgagttt
gaagcgctgggcgtgaccttaccgatcatgatttccggcaccatcaccgacgcctctggc
cgcaccctttccggtcagactacggaagcgttctacaactcgctgcgtcacgttaaaccg
ctgacctttggtttgaactgtgcgcttggcccggatgagttacgccaatacgtggcggaa
ttgtctcgcatctctgaaagctatgtgaccgcccacccgaacgccggtttgcccaatgcc
tttggtgaatacgatctcgatgccgaagagatggccaaacaggtgggcgaatgggcgcac
gccggtttcctcaatattatcggtggctgctgtggcaccacaccggcgcatattgccgcg
atggctaaagcggtcgagggtgtaccgccgcggcagttgccagagttaccggtggcttgc
cgcctgtccggcctggaaccgctgaatattgatgccaaatcgctgttcgtcaacgtgggt
gaacgtactaacgttaccggctcggcccgtttcaagcggctgattaaagaagaaaagtat
aacgaggcgctggccgtggcccgccaacaggtggagagcggtgcccaaatcatcgacatc
aacatggatgaagggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatc
gccggtgagccggacatagcccgcgtcccgatcatgatcgactcctctaaatggagcgtt
atagaaaagggcctgaaatgcattcagggtaaaggcatcgtcaactcaatctcgatgaaa
gagggcgaagaagcctttatccaccatgccaaactggtgcgccgctacggtgccgccgtg
gtggtgatggccttcgatgaagttggccaagcggatacccgccaacgcaaatttgagatt
tgccgccgtgcttaccagatcctgaccgaacgagtgggttttccgccggaagacatcatc
tttgacccgaacatttttgccgtcgcaaccggtatcgaagagcataacaactatgccgtc
gactttatcgaagcctgcgccgacatcaaaacccacctgccacacgcgatgatctccggc
ggcgtgtccaacgtctccttctcgttccgtggcaacgatccggtgcgtgaagcgatccac
gcggtgttcctgtatcacgccattcgcaatggtatggatatggggatcgtcaacgccggg
cagttggcgatctatgacgatctcagcaccgaactgcgtgaagccgttgaggatgtggtg
ctcaaccgccgtcaggacggcaccgagcgtctgctagaactggcggagaaataccggggt
agcaaagacaatgaagtggcggtgcagcaggccgaatggcgcggctggccggtagtgaag
cgcctggagtattcgctggtcaaaggcattaccgaatttattgagttagacaccgaagaa
gcgcgccagcaggcggatcgcccgatcgaagtgatcgaagggccgctgatggccggcatg
aacgtggttggtgacctgttcggcgagggcaaaatgttcttgccgcaggtagtgaaatcg
gcccgcgtgatgaagcaggcggtggcctatctcgaaccttacattgaggccagcaaacag
aaaggcaccaccgccgggaaaattctgctggcgacggtgaagggcgacgtgcacgacatc
ggcaaaaacatcgtcggcgtggtgctgcaatgtaacaactacgaaattatcgatctgggc
gtgatggtgccgacggacaaaatcctgaaaaccgcccgcgaacagaacgtggatattatc
ggtctgtctggcctgatcaccccgtcgctggacgaaatggtgaacgtggcaaaagagatg
gagcgccaaggctttactctgccgctgctgatcggcggggcgaccacctccaaggcccat
accgcggtgaagattgagcagaactacagcggctcgactacctacgtgcagaatgcctcg
cgtaccgttggcgtggttgcggcgctgctatcagacacccagcgcgacgagtttgtcgcc
cgcactcgcaaagagtacgaaaccgtgcgtatccagcacgggcgtaaaaagccgcgtacg
ccgccggtcagcctgcaacaggcgcgggataacgctatggtgctggattgggaaaactac
cagccaccggtaccgaacaagttgggggtgttcccggttgaggccagcattaacacgctg
cgccactatatcgactggacgccgttctttatgacctggtcgctggcgggcaagtatccg
cgcattctggaggatgaagtggtaggggaagaggccaagcgcctgttccaggatgccaac
gaaatgctggatatgctggccgctactggcaccctcaacccgcgtggcgtctatggcctg
ttcccggctaaccgcgttggggatgatgtggaagtctatcgggatgaaagccgtgaagag
gtgctggtggtcagccgccatctgcgtcagcaaaccgaaaagactgatttcccgaactac
tgtctggctgactttgtggccccgaaaagcagcggcaaagccgactattttggcgcattc
gcggtcacgggtgggttggaagaagatgcattggcagcggcctatgatgccaaacatgat
gattacaacaagatcatggtcaaagcgttatccgatcgtctggcagaggcctttgccgaa
tacctgcacgagcaggtgcgcaagctgcattggggctttgccgccgatgaaaatctgagt
aacgaagagctgatccgtgagaattatcaaggcattcgcccggcccccggctatcctgct
tgcccagaacataccgaaaaagcggagatctggcagttgctggacgttaaccgccatacc
ggcatggaactgaccgaatccttcgccatgtggcctggagcggcggtctccggctggtat
ttcagccatccgcagagcaagtactttgccgtggcacaaatccagcgcgatcaggtcgaa
gactacgcgcagcgtaaggggatgaagatcagtgacgtagagcgctggctggccccgaac
ctagggtacgatgcagattaa
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