Shigella flexneri 2457T (serotype 2a): S0047 Help Entry S0047             CDS       T00128                                  Symbol folA Name (GenBank) dihydrofolate reductase type I   KO K00287   dihydrofolate reductase [EC:1.5.1.3] Organism sfx  Shigella flexneri 2457T (serotype 2a) Pathway sfx00670   One carbon pool by folate sfx00790   Folate biosynthesis sfx01100   Metabolic pathways sfx01240   Biosynthesis of cofactors sfx04981   Folate transport and metabolism Module sfx_M00126   Tetrahydrofolate biosynthesis, GTP => THF Brite KEGG Orthology (KO) [BR:sfx00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     S0047 (folA)    00670 One carbon pool by folate     S0047 (folA)  09150 Organismal Systems   09154 Digestive system    04981 Folate transport and metabolism     S0047 (folA) Enzymes [BR:sfx01000]  1. Oxidoreductases   1.5  Acting on the CH-NH group of donors    1.5.1  With NAD+ or NADP+ as acceptor     1.5.1.3  dihydrofolate reductase      S0047 (folA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DHFR_1 Motif Other DBs NCBI-ProteinID:  AAP15591 UniProt:  P0ABQ6 LinkDB All DBs Position 48627..49106 Genome browser AA seq 159 aa AA seqDB search MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR NT seq 480 nt NT seq  +upstreamnt  +downstreamnt atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg attatgggccgccatacttgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaaatcggtggatgaa gccattgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat gagcagttcctgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc cacgacgccgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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