Shigella flexneri 2457T (serotype 2a): S3645
Help
Entry
S3645 CDS
T00128
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sfx
Shigella flexneri 2457T (serotype 2a)
Pathway
sfx00270
Cysteine and methionine metabolism
sfx00450
Selenocompound metabolism
sfx00670
One carbon pool by folate
sfx01100
Metabolic pathways
sfx01110
Biosynthesis of secondary metabolites
sfx01230
Biosynthesis of amino acids
sfx04980
Cobalamin transport and metabolism
sfx04981
Folate transport and metabolism
Module
sfx_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sfx00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
S3645 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
S3645 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
S3645 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
S3645 (metH)
04980 Cobalamin transport and metabolism
S3645 (metH)
Enzymes [BR:
sfx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
S3645 (metH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AAP18689
UniProt:
A0A9P2MXP4
LinkDB
All DBs
Position
complement(3527156..3530839)
Genome browser
AA seq
1227 aa
AA seq
DB search
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLAAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAQ
AGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKADDTANAQQAEWRSWDVN
KRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRIAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFAIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTCKEYETVRIQHGRKKPR
TPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYP
ACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDHARRKGMSVSDVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagtggaacaactgcgtgcgcagttaaatgaacgtattctggtgttggac
ggcggtatgggcaccatgatccagagctatcgactgaacgaagccgattttcgtggtgaa
cgctttgccgactggccatgcgacctcaaaggcaacaacgacctgctggtactcagtaaa
ccggaagtgatcgccgctatccacaacgcctactttgaagcgggcgcggatatcatcgaa
accaacaccttcaactccacgaccattgcgatggcggattaccagatggaatccctgtcg
gcggaaatcaactttgcggcggcgaaactggcgcgcgcctgtgctgacgagtggaccgcg
cgcacgccggagaaaccgcgctacgttgccggtgttcttggcccaaccaaccgcacggcg
tctatttctccggacgtcaacgatccggcattccgcaacatcacttttgaccagctggcg
gcggcctatcgcgaatccaccaaagcgctggtggaaggtggtgcggatctgatcctgatt
gaaaccgttttcgacacccttaacgccaaagcggcggtctttgcggtgaaaacggagttt
gaagcgctgggcgttgagctgccgattatgatctccggcaccatcaccgacgcctccggg
cgcacgctctccgggcagaccaccgaagcattttacaactcattgcgccacgccgaagcg
ctgacctttggcctgaactgtgcgctggggcccgatgaactgcgccagtacgtgcaggaa
ctatcacggattgcggaatgctacgtcaccgcccacccgaacgccgggctgcctaacgcc
tttggtgaatacgatctcgacgccgacacgatggcaaaacagatacgtgaatgggcgcaa
gcgggctttctcaatatcgtcggtggttgctgcgggaccacgccgcaacatattgcagcg
atgagtcgtgcagtagaaggattagcgccgcgcaaactgccggaaattcccgtagcctgc
cgtttgtctggcctggagccgctgaacattggcgacgatagcctgtttgtgaacgtgggt
gaacgcaccaacgtcaccggctctgctaagttcaagcgcctgatcaaagaagagaaatac
agcgaggcgctggatgtggcgcgtcagcaggtggaaaacggcgcgcagattatcgatatc
aacatggatgaagggatgctcgatgccgaagcggcgatggtgcgttttctcaatctgatt
gccggtgaaccggatatcgctcgcgtgccgattatgatcgactcctcaaaatgggatgtc
attgaaaaaggtctgaagtgtatccagggcaaaggcattgttaactctatctcgatgaaa
gagggcgtcgacgcctttatccatcacgcgaaattgttgcgtcgctacggtgcggcagtg
gtggtgatggcctttgacgaacagggacaggccgatactcgcgcacggaaaatcgagatt
tgccgtcgggcgtacaaaatcctcaccgaagaggttggcttcccgccagaagatatcatc
ttcgacccgaacatcttcgcggtcgccaccggtattgaagagcacaacaactacgcgcag
gactttatcggcgcgtgtgaagacatcaaacgcgaactgccgcacgcgctgatttccggc
ggcgtatctaacgtttctttctcattccgtggcaacgatccggtgcgcgaagccattcac
gcagtgttcctctactacgctattcgcaatggcatggatatggggatcgtcaacgccggg
caactggcgatttacgacgacctacccgctgaactgcgcgacgcggtggaagatgtgatt
cttaatcgtcgtgacgatggcactgagcgtttactggagcttgccgagaaatatcgcggc
agtaaagcggacgacactgctaacgcccagcaagcggagtggcgctcgtgggacgtgaat
aaacgtctggaatactcgctggtcaaaggcataaccgagtttatcgagcaggatactgaa
gaagcccgccagcaggctacgcgcccgattgaagtgattgaaggcccgttgatggacggc
atgaacgtggtcggcgatctgtttggcgaaggcaaaatgttcctgccacaggtggtcaaa
tcggcgcgcgtcatgaaacaggcagtggcgtatctcgaaccgtttattgaagccagcaaa
gagcagggtaaaaccaacggcaagatggtgatcgccaccgtgaaaggcgatgtccacgac
atcggtaaaaatatcgttggtgtggtgctgcaatgtaacaactacgaaattgtcgatctc
ggcgttatggtgcctgcggaaaaaattctccgtatcgccaaagaagtgaatgctgatttg
attggcctttcggggcttatcacgccgtcgctggacgagatggttaacgtggcgaaagag
atggagcgtcagggcttcgccattccgttactgattggcggcgcgaccacctcaaaagcg
cacacggcggtgaaaatcgagcagaactacagcggccctacggtgtatgtgcagaatgcc
tcgcgcaccgttggtgtggtagcggcgctgctttccgatactcagcgtgatgattttgtc
gctcgtacctgcaaggagtacgaaaccgtgcgtattcagcacgggcgcaagaaaccacgc
acaccaccggtcacgctggaagcggcgcgcgataacgatttcgcatttgactggcaggct
tacacgccgccggtggcgcaccgtctcggcgtgcaggaagtggaagccagcatcgaaacg
ctgcgtaattacatcgactggacaccgttctttatgacctggtcgctggccgggaagtat
ccgcgcattctggaagatgaagtggtgggcgttgaggcgcagcggctgtttaaagacgcc
aacgacatgctggataaattaagcgccgagaaaacgctgaatccgcgtggcgtggtgggc
ctgttcccggcaaaccgtgtgggcgatgacattgaaatctaccgtgacgaaacgcgcacc
catgtgatcaacgtcagccaccatctgcgtcaacagaccgaaaaaacgggattcgctaac
tactgtctcgctgacttcgttgcgccgaagctttctggtaaagcagattacatcggcgca
tttgccgtgactggcgggctggaagaggacgcactggctgatgcctttgaagcgcagcac
gatgattacaacaaaatcatggtgaaagcgcttgccgaccgtttagccgaagcctttgcg
gagtatctccatgagcgtgtgcgtaaagtctactggggctatgcgccgaacgagaacctc
agcaacgaagaactgatccgcgaaaactaccagggcatccgtccggcaccgggctatccg
gcctgcccggaacatacggaaaaagccaccatctgggagctgctggaagtggaaaaacat
actggcatgaaactcacagaatctttcgcgatgtggcctggtgcatcggtttcgggttgg
tatttcagtcatccggacagcaagtactacgcggtggcgcaaattcagcgcgatcaggtt
gaagaccatgcccgccgtaaaggtatgagcgtctccgatgttgagcgctggctggcaccg
aatctggggtatgacgcggactga
DBGET
integrated database retrieval system
