Streptomyces globisporus: WQO_09695
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Entry
WQO_09695 CDS
T04209
Name
(GenBank) alpha-ketoglutarate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgb
Streptomyces globisporus
Pathway
sgb00010
Glycolysis / Gluconeogenesis
sgb00020
Citrate cycle (TCA cycle)
sgb00620
Pyruvate metabolism
sgb00785
Lipoic acid metabolism
sgb01100
Metabolic pathways
sgb01110
Biosynthesis of secondary metabolites
sgb01120
Microbial metabolism in diverse environments
sgb01200
Carbon metabolism
sgb01210
2-Oxocarboxylic acid metabolism
Module
sgb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
WQO_09695
00020 Citrate cycle (TCA cycle)
WQO_09695
00620 Pyruvate metabolism
WQO_09695
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
WQO_09695
Enzymes [BR:
sgb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
WQO_09695
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ALU93609
UniProt:
A0A0U3LNB5
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Position
2202735..2205467
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETKEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGDEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDQGDGGDQIFFQGHASPGIYARAFLLDRLSEAQLDAFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRTGILVNKLNTTPDGQFQTYATETGAYIREHFFGDDPRLR
DMVKDMTDQQILHLGRGGHDHRKVYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVEDLKRFRDRLHIPITDKQLDEGYPPYYHPGRDSEEIQYMHDRRQGLGGYVP
TRVVRAKPLPQPADKTYAAAKKGSGSQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSRGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIMQDGLRRMYGEANEDVFYYLTVYNEPIQHPAEPE
NVDVEGILKGIHRFSTGEKGEIPAQIMASGVAVPWALEAQKILADEWNVKADVWSATSWN
ELRRDAVDVERHNLLHPEEEQRVPYVTKKLEGAQGPFVAVSDWMRSVPDQIARWVPGAYQ
SLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAKEGKVDRSALKKAVDRYELLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttccgagccaggtcccg
gactttgatcccgaggagaccaaggaatggctcgactccctcgacgccgccgtcgacgag
cgcggccgtgagcgggcccgctacctgatgctccggctcatcgagcgcgcgcgtgagaag
cgcgtcgccgtgccggagatgcgcagcacggactacgtgaacacgatcgccacgaaggac
gagccgttcttccccggcgacgaggagatcgagcgcaaggtcctcaacgcgacccgctgg
aacgccgccgtgatggtctcgcgggcccagcgtcccgggatcggcgtcggcggccacatc
gccaccttcgcctcctccgcctcgctgtacgacgtgggcttcaaccacttcttccggggc
aaggaccagggcgacggcggcgaccagatcttcttccaggggcacgcgtccccggggatc
tacgcccgcgcgttcctgctggaccggctgagcgaggcgcagctcgacgccttccgccag
gagaagtcgaaggccccgaacggtctgtccagctacccgcacccgcggctcatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgctcggcgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgccgacacgtccaagtcgcacgtctgg
gcctatctgggcgacggcgagatggacgagccggagtcgctgggccagctgtccatcgcg
gcccgtgagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcggctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgcagttccggggcgcc
ggctggaacgtcatcaagctggtctgggaccgttcctgggacccgctgctggcgcaggac
cgcacgggcatcctggtcaacaagctgaacaccacgccggacggccagttccagacgtac
gcgaccgagaccggtgcgtacatccgcgagcacttcttcggcgacgacccgcggctgcgg
gacatggtcaaggacatgaccgaccagcagatcctgcacctgggccgcggcggtcacgac
caccgcaaggtctacgcggcctacgcggcggccaaggcgcacaagggccagccgacggtc
atcctggcgcagacggtcaagggctggacgctggggccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctcacggtcgaggacctcaagcgcttccgggaccgcctgcac
atcccgatcacggacaagcagctggacgagggctacccgccctactaccacccgggccgc
gactcggaggagatccagtacatgcacgaccgccggcagggtctgggcggttacgtcccg
acccgggtggtccgggcgaagccactgccgcagcccgcggacaagacgtacgcggccgcg
aagaagggttcgggttcgcagtcgatcgccaccaccatggcgttcgtccgcatcctgaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcccccgacgagtac
cgcaccttcggcatggatgcgttcttcccgagtgcgaagatctacaacccgttgggtcag
cagtacgaggcggtcgaccgggagctgctgctcgcgtacaaggagtccccgacgggccag
atgctgcacgacggcatctccgaggcgggctgcacggcctcgctgatcgcggccggttcg
gcgtacgccacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggg
ttccagcggaccggcgaccagttctggcagatggccgaccagctctcgcgcggcttcgtg
ctgggcgcgaccgccggccgcaccacgctgaccggtgagggcctccagcacgcggacggc
cactcgcagctgctcgcctcgacgaacccgggctgtgtcgcgtacgacccggccttcggg
ttcgagatcgcgcacatcatgcaggacgggctccgccggatgtacggcgaggcgaacgag
gacgtcttctattacctcaccgtctacaacgagccgatccagcacccggccgagccggag
aacgtggacgtcgagggcattctcaagggcatccaccgcttctccaccggcgagaagggc
gagatcccggctcagatcatggcgtcgggcgtggcggtcccctgggccctggaggcgcag
aagatcctcgcggacgagtggaacgtcaaggcggacgtctggtcggcgacctcctggaac
gagctgcgccgcgacgcggtggacgtggagcgccacaacctcctgcacccggaggaggag
cagcgcgtcccgtacgtgaccaagaagctcgaaggggcccagggtccgttcgtggcggtc
tcggactggatgcgttcggtgccggaccagatcgcgcgctgggtgccgggcgcgtaccag
tcgctgggcgcggacggcttcggcttcgcggacacccggggtgcggcccgccggttcttc
cacatcgacgcgcagtcgatcgtgctggcggtgctgaccgagctggccaaggagggcaag
gtcgaccggtcggccctgaagaaggccgtcgaccgctacgagctcctggacgtggccgcg
gccgatccgggcgcggcgggcggcgacgcgtag
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