Streptomyces globisporus: WQO_24325
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Entry
WQO_24325 CDS
T04209
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sgb
Streptomyces globisporus
Pathway
sgb00020
Citrate cycle (TCA cycle)
sgb00630
Glyoxylate and dicarboxylate metabolism
sgb00785
Lipoic acid metabolism
sgb01100
Metabolic pathways
sgb01110
Biosynthesis of secondary metabolites
sgb01120
Microbial metabolism in diverse environments
sgb01200
Carbon metabolism
sgb01210
2-Oxocarboxylic acid metabolism
Module
sgb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sgb_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sgb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
WQO_24325 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
WQO_24325 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
WQO_24325 (kgd)
Enzymes [BR:
sgb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
WQO_24325 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
WQO_24325 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
WQO_24325 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
WQO_24325 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ALU96169
UniProt:
A0A0U3LVG8
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Position
complement(5480289..5484113)
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AA seq
1274 aa
AA seq
DB search
MSSQSPSNSSVSTDQASPGTNPAAAFGANEWLVDEIYQQYLQDPSSVDRAWWDFFADYKP
GAAGTADKPAPGASGAPVTEAAAPAAPAPAAAPAPAKAAPTAAPAAPAQPAPAKAAPAPA
KAAPAEAKPAAAKPAAAPAKAKPKADESTEAPAGPEYVTLRGPSAAVAKNMNASLELPTA
TSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNYSFAEKDGK
PTLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARIGKLGM
DDFTGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLGISKV
MTLTSTYDHRVIQGAASGEFLRVLSQLLLGENEFYDEIFKALRIPYEPVRWLKDIDASHD
DDVTKAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLERDFAVGGF
AGKTMMKLRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERPRPKPEREEQLRILR
RLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLN
VLANIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSH
LEAVDPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTG
GTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEFRQ
AFNKDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGDITLEEA
EQALQDFQGQLEKVFAEVREATSQPASPHVPEPQAAFPVAVETAVSAEVVKRIAESQVNI
PESITVHPRLMPQMQRRAASVENATIDWGMGETLAIGSLLMEGTPVRLAGQDTRRGTFGQ
RHAVLVDQVTGEDYTPLLYLADDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVIWEAQ
FGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDN
MTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASSIEEFTTGGFRPVIGD
VSVKAEDVRKVVFVSGKLYYDLDAEREKRGDTETAIIRLERLYPLPGAEIQAEIAKYPNA
EKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRH
QAEQTQLVNEVFEA
NT seq
3825 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactccagcgtctcgaccgaccaagccagcccgggcacc
aacccggccgcggctttcggcgccaatgaatggctcgtcgacgagatctaccagcagtac
ctccaggaccccagttcggtcgatcgtgcctggtgggacttcttcgccgactacaagccg
ggtgccgccggcacggcggacaagcccgctcccggggcctcgggggccccggtgaccgag
gccgccgccccggccgcgcccgctccggcagccgctccggctccggcgaaggccgcgccc
accgccgctccggccgcccccgcgcagccggccccggccaaggccgcgcccgctccggcg
aaggccgcccccgccgaggcgaagcccgcggccgcgaagcccgccgccgcgcccgccaag
gcgaagcccaaggcggacgagtccaccgaggccccggcgggtccggagtacgtgacgctg
cgcggcccctcggccgccgtcgcgaagaacatgaacgcctcgctggagctgccgacggcc
acgtccgtccgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaac
cacctcaagcgcgcccgcggcgggaagatctccttcacgcacctcatcgggtacgcgatg
gtgcaggccctcaaggccatgccgtcgatgaactactccttcgcggagaaggacggcaag
ccgaccctggtcaagccggagcacgtcaacctgggtctggccatcgacctggtgaagccg
aacggcgaccgccagctggtcgtcgcggccatcaagaaggccgagacgctcaacttcttc
gagttctggcaggcgtacgaggacatcgtccggcgcgcccgcatcggcaagctcggcatg
gacgacttcaccggcgtcaccgcctcgctgaccaaccccggcggcatcggcaccgtccac
tcggtgccccgcctgatgcccggtcagggcctcatcatgggcgtcggcgcgatggactac
ccggctgagttccagggcacctcgcaggacaccctcaacaagctcggcatctcgaaggtc
atgacgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttc
ctgcgcgtcctgtcccagctgctgctcggcgagaacgagttctacgacgagatcttcaag
gcgctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgac
gacgacgtcaccaaggccgcgcgggtcttcgagctgatccactcctaccgggtccgcggc
cacgtcatggccgacaccgacccgctggagtaccaccagcgcaagcaccccgacctggac
atcaccgagcacggcctcaccctgtgggacctggagcgggacttcgcggtcggcgggttc
gccggcaagacgatgatgaagctccgcgacatcctcggcgtgctccgtgagtcgtactgc
cgcaccaccggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggctccag
gaccgggtggagcgcccgcgcccgaagcccgagcgcgaggagcagctgcgcatcctgcgc
cggctgaacgccgcggaggcgttcgagaccttcctgcagacgaagtacgtcggccagaag
cggttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactcc
gccgccgaggcccgcctcgacgaggtcgtcatcggcatggcccaccgcggccggctgaac
gtcctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaac
ctcgacccgcgctccatgcacggctccggcgacgtcaagtaccacctgggcgccgagggc
accttcaccggtctggacggcgagcagatcaaggtctcgctggccgccaacccctcgcac
ctggaggcggtcgacccggtcctggagggcatcgcccgcgccaagcaggacatcatcaac
aagggcggcacggacttcacggtcctgccggtcgcgctccacggcgacgcggccttcgcg
ggccagggcgtcgtcgccgagacgctcaacatgtcgcagctgcgcggctaccgcaccggc
ggcaccgtgcacgtggtgatcaacaaccaggtcggcttcaccgccgccccggagtcctcg
cgctcctcgatgtacgccaccgacgtggcgcgcatgatcgaggcgccgatcatccacgtc
aacggcgacgacccggaggccgtggtccgcgtcgcgcggctcgccttcgagttccggcag
gcgttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgag
ggcgacaacccggagttcaccaacccgcagatgtacaccctgatcgacaagaagcgctcg
gtgcgcaagctctacaccgagtccctcatcggtcgtggcgacatcacgctggaagaggcg
gagcaggcgctccaggacttccagggtcagctggagaaggtgttcgccgaggtccgcgag
gccacctcgcagccggcgtccccgcacgtgccggagccgcaggccgcgttcccggtggcc
gtggagacggcggtctccgccgaggtcgtcaagcggatcgccgagtcccaggtcaacatc
cccgagtcgatcaccgtccacccccgtctgatgccgcagatgcagcgtcgcgcggcctcg
gtggagaacgccacgatcgactggggcatgggcgagaccctggccatcggttcgctgctg
atggagggcaccccggtccggctcgccggccaggacacccgccgcggcacgttcggccag
cgccacgcggtcctggtcgaccaggtcaccggcgaggactacaccccgctgctgtacctg
gcggacgaccaggcccgctacaacgtctacgactcgctgctcagcgagtacgcggcgatg
ggcttcgagtacggctactcgctggcccgtccggagtcgctggtcatctgggaggcccag
ttcggtgacttcgtcaacggcgcgcagaccgtcgtggacgagttcatctcctcggccgag
cagaagtggggccagacctccggcgtcacgctgctgctgccgcacggctacgagggccag
ggcccggaccacagctccgcccgccccgagcgcttcctccagatgtgcgcgcaggacaac
atgacggtcgcgatgccgaccctgccgtcgaactacttccacctgctgcgctggcaggtg
cacaacccgcaccacaagccgctcatcgtcttcaccccgaagtcgatgctgcgtctgaag
gcggcggcctcgtccatcgaggagttcaccaccggcggcttccgcccggtgatcggcgac
gtgtcggtcaaggccgaggacgtccgcaaggtcgtcttcgtctccggcaagctgtactac
gacctggacgccgagcgggagaagcgcggcgacacggagacggcgatcatccggctggag
cgcctgtacccgctgccgggtgcggagatccaggccgagatcgcgaagtacccgaacgcc
gagaagtacctgtgggcgcaggaggagccggcgaaccagggtgcgtggccgttcatcgcg
ctcaacctgatcgaccacctggacctcgcggtcggcgcggacgtgccgcacggcgagcgc
ctgcgccgcatctcgcggccgcacggctcgtccccggcggtcggctcggccaagcgtcac
caggcggagcagacgcagctggtcaacgaggtcttcgaggcctga
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