Streptomyces griseorubiginosus: DWG14_02860
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Entry
DWG14_02860 CDS
T06099
Symbol
kgd
Name
(GenBank) Multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sge
Streptomyces griseorubiginosus
Pathway
sge00020
Citrate cycle (TCA cycle)
sge00630
Glyoxylate and dicarboxylate metabolism
sge00785
Lipoic acid metabolism
sge01100
Metabolic pathways
sge01110
Biosynthesis of secondary metabolites
sge01120
Microbial metabolism in diverse environments
sge01200
Carbon metabolism
sge01210
2-Oxocarboxylic acid metabolism
Module
sge_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sge_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
DWG14_02860 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
DWG14_02860 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DWG14_02860 (kgd)
Enzymes [BR:
sge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
DWG14_02860 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
DWG14_02860 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
DWG14_02860 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
DWG14_02860 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AYC38630
UniProt:
A0AAI8PN33
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All DBs
Position
3306596..3310420
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AA seq
1274 aa
AA seq
DB search
MSPQSPSNSSISTDADQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAGAPAPAGTAAAGAAGTTTPAPAAAAPAQAPAPAAPAVPAPAAAKPAAAPAPAQAAAP
AAPAQAAPAAKPAAAPAKPAAAKPAAQASSPEGPELITLRGPAAAVAKNMNASLELPTAT
SVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWHYAEKDGKP
TLVKPPHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLTMD
DFSGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVM
TLTSTYDHRVIQGAASGEFLRIVANLLLGENGFFDEIFEALRIPYEPVRWLKDIDASHDD
DVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFA
GKSLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRRWIQDRIERSHTKPEREEQLRILRR
LNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNV
LANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHL
ETVDPVIEGIVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGG
TVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQA
FNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAE
QALQDYQGQLEKVFTEVREAVTAQPAAGPVSDPQAEFPVAVNTAISTETVKRIAESQVNI
PDTFHVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLEGTPVRLSGQDSQRGTFGQ
RHAVLIDRETGEEHTPLQYLAEEQARYNVYNSLLSEYAVMGFEYGYSLARPDALVMWEAQ
FGDFVNGAQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQNN
MTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTSGQFRPVIGD
ATVDPAAVRKVVFVAGKLYYDLEAERQKRGITDTAIIRIERLYPLPGAELQAEIAKYPNA
EKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRH
QAEQEQLVREVFEA
NT seq
3825 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacgcagaccaagcgggcaag
aaccccgctgccgcgttcggcccgaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggtgctgcgggcgctccggctccggcgggtactgcggccgcgggggccgcagggaccacc
accccggctccggccgccgcggctccggcccaggctcccgcgccggccgctcctgccgtg
ccggctcccgccgccgcgaagcccgccgccgctccggctcccgcgcaggccgccgcgccc
gccgccccggcccaggcggctccggccgccaagccggcggccgctcccgcgaagcccgcc
gccgcgaagccggccgcgcaggcctcctcgccggagggcccggagctgatcacgctgcgc
ggtcccgccgccgcggtcgcgaagaacatgaacgcctccctggagctgcccacggccacg
tccgtgcgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccac
ctcaagcgcgcccggggcgggaagatctccttcacgcacctgatcggctacgcgatggtg
caggccatcaaggccatgccgtcgatgaactggcactacgcggagaaggacgggaagccc
accctcgtcaagccgccgcacgtcaacttcggcctcgccatcgacctggtgaagcccaac
ggcgaccgtcagctggtcgtcgcgggcatcaagaaggccgagacgctgaacttcttcgag
ttctggcaggcctacgaggacatcgtccgccgcgcccgtgacggcaagctgacgatggac
gacttctcgggcgtcaccgtctccctgaccaaccccggcggcctcggtacggtccactcc
gtgccgcgtctgatgcccggccagtcggtcatcatgggcgtcggctccatggactacccg
gcggagttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatg
acgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctg
cggatcgtcgcgaacctcctgctcggcgagaacggcttcttcgacgagatcttcgaggcc
ctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgac
gacgtcaccaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccac
gtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctggacatc
accgagcacggcctcaccctgtgggacctggagcgggagttcgcggtcggcggtttcgcc
ggcaagtccctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgc
accaccggcgtcgagttcatgcacatccaggacccgaagcagcgccgctggatccaggac
cgcatcgagcgctcccacaccaagccggagcgcgaggagcagctgcgcatcctgcgccgg
ctgaacgccgccgaggcgttcgagaccttcctccagacgaagtacgtcggccagaagcgc
ttctccctggagggcggcgagtccgtcatcccgctgctcgacgcggtcctcgactcggcc
gccgagtcgcgcctggacgaggtcgtcatcggcatggcccaccgcggccgcctgaacgtc
ctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctc
gacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcacc
ttcaccggtctggacggcgagcagatcaaggtctcgctggccgcgaacccctcccacctg
gagacggtcgacccggtcatcgagggcatcgtccgcgccaagcaggacatcatcaacaag
ggcggcacggacttcaccgtcctgccggtcgccctgcacggcgacgcggccttcgcgggc
cagggcgtggtggccgagaccctgaacatgtcgcagctgcggggctaccgcaccggcggc
acggtccacatcgtcatcaataaccaggtcggcttcacggcggcgccggagtcctcgcgc
tcgtccatgtacgccaccgacgtggcccgcatgatcgaggccccgatcttccacgtgaac
ggcgacgacccggaggccgtggtccgcgtggcccgcctggccttcgagttccgccaggcg
ttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcg
gacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtg
cgcaagctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggcggag
caggcgctccaggactaccagggccagctggagaaggtcttcaccgaggtccgcgaggcc
gtcacggcccagccggccgccggtcccgtctccgacccgcaggccgagttcccggtcgcc
gtgaacaccgcgatctccacggagaccgtgaagcggatcgccgagtcccaggtcaacatc
ccggacaccttccacgtccacccgcgtctgctgccgcagctccagcggcgcgcggccatg
gtcgaggacggcaccatcgactggggcatgggcgagaccctcgccgtcggttcgctgctc
ctggagggcaccccggtccgcctgtcgggccaggactcccagcgcggcaccttcggccag
cgccacgcggtcctcatcgaccgcgagaccggcgaggagcacaccccgctccagtacctc
gccgaggagcaggcccgctacaacgtctacaactccctgctctccgagtacgcggtcatg
ggcttcgagtacggctactcgctggcccgtcccgacgcgctcgtgatgtgggaggcgcag
ttcggcgacttcgtcaacggcgcgcagacggtcgtcgacgagtacatctcggcggcggag
cagaagtggggccagacgagcggtgtcacgctcctcctgccgcacggctacgagggccag
ggcccggaccactcctcggcccgcgtcgagcggttcctccagctctgcgcccagaacaac
atgacggtcgcgatgccgaccctgccgtcgaactacttccacctcctgcggtggcaggtg
cacaacccgcaccacaagccgctggtggtcttcaccccgaagtcgatgctgcgtctgaag
gccgcggcgtcgaagacggaggagttcacctcgggtcagttccgcccggtcatcggcgac
gcgacggtggacccggccgcggtccgcaaggtcgtcttcgtggcgggcaagctgtactac
gacctcgaggccgagcgtcagaagcgcggcatcacggacacggcgatcatccgcatcgag
cgcctgtacccgctgccgggtgccgagctccaggcggagatcgccaagtacccgaacgcc
gagaagtacctgtgggcccaggaggagccggcgaaccagggtgcctggccgttcatcgcc
ctcaacctgatcgaccacctggacctcgcggtcggcgcggacgtcccgcacggcgagcgc
ctgcgccgcatctcccgcccgcactcgtcgtccccggcggtcggttccgcgaagcggcac
caggcggagcaggagcagctggtgcgtgaggtgttcgaggcgtaa
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