Streptomyces griseorubiginosus: DWG14_06145
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Entry
DWG14_06145 CDS
T06099
Symbol
aceE_2
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sge
Streptomyces griseorubiginosus
Pathway
sge00010
Glycolysis / Gluconeogenesis
sge00020
Citrate cycle (TCA cycle)
sge00620
Pyruvate metabolism
sge00785
Lipoic acid metabolism
sge01100
Metabolic pathways
sge01110
Biosynthesis of secondary metabolites
sge01120
Microbial metabolism in diverse environments
sge01200
Carbon metabolism
sge01210
2-Oxocarboxylic acid metabolism
Module
sge_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DWG14_06145 (aceE_2)
00020 Citrate cycle (TCA cycle)
DWG14_06145 (aceE_2)
00620 Pyruvate metabolism
DWG14_06145 (aceE_2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DWG14_06145 (aceE_2)
Enzymes [BR:
sge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DWG14_06145 (aceE_2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
AYC41854
UniProt:
A0AAI8PQZ1
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All DBs
Position
complement(6918112..6920817)
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AA seq
901 aa
AA seq
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MTDPNAIQASELDQLPDRDPEETAEWQASLDAVAKAAGPHRAAYLMRRTLERAEGNGIAL
PKLLETDYVNTIPTAAEPGLPGDPAMEARITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFKGKEADGSGDQLYIQGHASPGIYARAFLDGRLTEQQLDNFRRESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTARGIKDVSQSHVWAFLGDGEM
DEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSL
WGSAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGKDPALVEMAKLLSD
DKILECFHLSRGGHEASKVYAAYKAAVEFKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLTVDEFKTMRDLLELPISDAQFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPAPAEKAFASFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTSYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAAIVRDGIRRMYGEAAPGEDPNVFYYLTVYNEPLPQPAKPS
VAGIDEGIVKGLYRFNTVESAGIGVAAANAPRIQLLGSGTAIHWVLKAQRMLAEEWGVAA
DVWSATSFTELRRDALEADEALLRGEERVPYVRQALHGAEGPVLAVSDYMRQVPDQIAQW
VEQDWSSLGADGFGLSDTREGARRHFGVDAESVVVAALAQLARRGEVKATAVKEAREKYG
L
NT seq
2706 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccaggccagcgagctcgaccagctccccgaccgggacccc
gaggagaccgccgaatggcaggcctccctggacgcggtcgccaaggcggccggcccgcac
cgtgccgcgtacctgatgcgccgcacgctggagagggcggagggcaacggcatcgcgctg
ccgaagctcctcgagaccgactacgtcaacaccatccccaccgccgcggagccgggcctg
cccggtgacccggcgatggaggcccgcatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccgcggctccaagtacggcgtcggtggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttcaagggcaaggaggccgacgggtcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgcctttctc
gacggccggctgaccgagcagcagctcgacaacttccgccgcgagtcgggcggcaacggc
ctgccgtcgtacccgcacccccgccggctgccctggctctgggagttcccgaccgtctcc
atgggcctcggcccgctctcggcgatctaccaggcccgcttcaaccgctatctgacggcg
cgcggcatcaaggacgtctcgcagtcccacgtctgggccttcctcggcgacggcgagatg
gacgagccggagtccacggccgccctcgcactcgcgagccgcgagggtctcgacaacctg
accttcgtcatcaactgcaacctccagcgcctcgacggcccggtccgcgcgaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtcaagtcgctg
tggggctccgcctgggacgagctgttccagctggacaccaccggcgccctggtacgacgg
ctccgcgaggtaccggacgcgcaggtgcagacgtaccagacgcgtgacgccgcctacatc
cgccaggacttcttcggcaaggacccggcgctcgtcgagatggcgaaactgctctccgac
gacaagatcctcgagtgcttccacctctcgcgcggtggccacgaggcgagcaaggtgtac
gccgcctacaaggccgccgtcgagttcaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaagacgatgcgtgaccttctcgaactccccatctccgac
gctcagttcgtcgacggggtcgttccctacggccaccccggtgccgactcccccgaggtg
cgctacctccaggagcgccgcgcggccctcggcggtcccgccccggcccgccgcgtccac
ccggtggctccgctgccggcccccgcggagaaggcgttcgcctccttcgacaagggctcc
ggctcgcagaacgtggcgaccacgatggccttcgtccggctcgtcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagagcctcttcccgtccctcgggatctactcccccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaagaacggccagatcctcaacgag
gggatcaccgaggccggttcgatggccgacttcatcgccgcttcgacgtcgtacgcgacg
cacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctgggccgcggcttcctcgtcggcgccacg
gcgggccgcaccacgctgacgggcgagggcctccagcacgcggacggccactccccggtc
atcgcggcgacgaacccggcggcactgacgtacgacccggcgttcgcctacgaggtcgcc
gcgatcgtgcgcgacggcatccgccggatgtacggcgaggcggccccgggtgaggacccg
aacgtcttctactacctcaccgtctacaacgagccgctcccgcagccggcgaagccgtcc
gtcgccggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacaccgtcgagtcg
gccgggatcggcgtggccgcggccaacgccccgcgcatccagctgctcggctccggcacc
gcgatccactgggtgctgaaggcgcagcggatgctggccgaggagtggggcgtggccgcc
gacgtgtggtccgcgacctccttcaccgagctgcgccgcgacgcgctggaggccgacgag
gccctgctgcgcggcgaggagcgggtcccctacgtccgtcaggcgctgcacggcgccgag
ggcccggtgctcgcggtctccgattacatgcgccaggtcccggaccagatcgcgcagtgg
gtcgagcaggactggtcctcgctcggcgcggacggcttcggcctctccgacacccgtgag
ggcgcccgccgccacttcggcgtcgacgccgagtcggtcgtggtcgcggccctggcccag
ctggcccgccgcggcgaggtcaaggcgacggcggtgaaggaagcacgggagaagtacggg
ctgtag
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