Streptomyces aurantiacus: GCM10017557_11400
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Entry
GCM10017557_11400 CDS
T07085
Name
(GenBank) squalene-hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
sgm
Streptomyces aurantiacus
Pathway
sgm00909
Sesquiterpenoid and triterpenoid biosynthesis
sgm01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sgm00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
GCM10017557_11400
Enzymes [BR:
sgm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
GCM10017557_11400
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
GCM10017557_11400
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
PGM1_C
Motif
Other DBs
NCBI-ProteinID:
BCL26281
UniProt:
A0A7G1NV13
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Position
complement(1374837..1376864)
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AA seq
675 aa
AA seq
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MTATTDGSTGALPPRAASASDIRTESTPAAAGTADVRDAAARAIQRATGFLLSTQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIDDEKTTHAAALFIRGEQREDGTWASFYGGPGELSTT
VEAYVALRLAGDAPDDPHMARAAAWIRERGGIAAARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPRDPNPVKPFAP
VASWDGVFQRLDRALHAYRKVAPRRLRRAAMNTAGRWIIERQENDGCWGGIQPPAVYSVI
ALYLLGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLGEEIVRPGDWAVKRPQLSPGGWAFEFHNDNYPDIDDTAEVVLALRRVK
HHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLAHDPRTRRGIEWLLAEQEENGSWFGRWGVNYVYGTGSVVPALVAAGLP
GSHPAIRRAVSWLETVQNEDGGWGEDLRSYHDVAEWSGRGESTASQTAWALLALLAAGEH
DSKAVERGVAWLARTQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FAGLQSSQSSFGRAS
NT seq
2028 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggagcactgccgccccgcgctgcctcggccagc
gacatccgtacagaatcgactcccgcggcagccgggacagccgatgtccgagacgccgcc
gcgcgcgcgatacagcgcgccaccggcttcctgctgagcacgcaggacgccgagggatgg
tggaagggcgacctggagaccaacgtcaccatggacgccgaagacctgctgctccgtcag
ttcctgggcatcgacgacgagaagaccacccacgccgcggccctgttcatccgcggcgag
cagcgcgaggacggcacctgggcctccttctacggcggaccgggcgaactctccaccacc
gtcgaggcgtacgtcgccctgcgccttgccggtgacgcgccggacgatccgcacatggcg
cgggccgccgcgtggatccgggagcggggcggcatcgccgcggcccgtgtcttcacccgg
atctggctcgccctgttcggctggtggaagtgggacgacctccccgaactccctccggaa
ctcatctacttcccgaagtgggcgccgctcaacatctacgacttcggctgctgggcccgg
cagaccatcgtgccgctcaccgtcgtctcggcgaagcgcccggtgcgccccgcgcccttc
gcgctggacgagctgcacaccgacccccgcgaccccaacccggtcaagcccttcgccccg
gtggcgagttgggacggggtgttccagcgcctcgaccgggccctgcacgcgtaccgcaag
gtcgcgccgcgcaggctccgcagggccgcgatgaacaccgcgggccgctggatcatcgag
cgtcaggagaacgacggctgctggggcggcatccagccgcccgccgtctactcggtcatc
gccctgtacctgctcggctacgacctcgaacacccggtgatgcgcgagggactggcctcc
ctggaccgcttcgccgtgtggcgcgaggacggggcccggatgatcgaggcctgtcagtca
ccggtctgggacacctgtctcgcgaccatcgcgctcgccgacgcgggcgtgcccgccgat
catccgcagctggtgagggccgcggactggatgctcggagaggagatcgtccgccccggc
gactgggcggtcaaaaggcctcaactctcgcccggcggctgggcgttcgagttccacaac
gacaactaccccgacatcgacgacaccgcagaggtggtcctcgcgctgcgccgcgtcaag
caccacgacccggagcgggtggagaaggccatcggacgcggggtgcgctggaacctcggc
atgcagtcgaagaacggcgcgtggggcgccttcgacgtcgacaacaccagccccttcccc
aatcggctgccgttctgcgacttcggcgaggtcatcgacccgccgtccgccgacgtcacc
gcgcacgtcgtggagatgctcgcggtcgaggggctcgcccacgacccgcgcacccgccgg
ggcatcgagtggctgctcgcggaacaggaggagaacggttcctggttcggccgctggggc
gtcaactacgtgtacgggacggggtcggtggtgcccgcgctggtcgccgccggactgccc
ggctcgcaccccgcgatccgccgggccgtgtcctggctggagaccgtacagaacgaggac
ggcggctggggcgaggacctgcgctcctaccacgacgtcgccgagtggagcgggcggggc
gagtcgaccgcctcccagaccgcgtgggcgctgctggcgctgctcgcggccggggagcac
gactccaaggccgtcgagcgcggcgtcgcctggctcgcccggacccagctggcggacggc
tcctgggacgagccgtacttcaccggcaccgggttcccgtgggacttctcgatcaactac
cacctctaccggcaggtgttcccgctcaccgcgctcggccggtacgtcaacggcgaaccg
ttcgccggcctgcagagctcccagagttccttcggcagggcgagctga
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