Streptomyces graminofaciens: SGFS_043340
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Entry
SGFS_043340 CDS
T09325
Name
(GenBank) Alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sgrf
Streptomyces graminofaciens
Pathway
sgrf00020
Citrate cycle (TCA cycle)
sgrf00630
Glyoxylate and dicarboxylate metabolism
sgrf00785
Lipoic acid metabolism
sgrf01100
Metabolic pathways
sgrf01110
Biosynthesis of secondary metabolites
sgrf01120
Microbial metabolism in diverse environments
sgrf01200
Carbon metabolism
sgrf01210
2-Oxocarboxylic acid metabolism
Module
sgrf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sgrf_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sgrf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SGFS_043340
00630 Glyoxylate and dicarboxylate metabolism
SGFS_043340
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SGFS_043340
Enzymes [BR:
sgrf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SGFS_043340
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SGFS_043340
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SGFS_043340
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SGFS_043340
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BBC33040
LinkDB
All DBs
Position
4983141..4986941
Genome browser
AA seq
1266 aa
AA seq
DB search
MSPQSPSNSSISTDADQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAASAPAGTAAAGAAATTTPAAPAAPAAPAAPAQTAPAQAAPKPAAAAPVPAAAKPAA
APAQPAAAAKLPGRPKAGEVTAAPDGPELITLRGPAAAVAKNMNASLELPTATSVRAVPV
KLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKTMPSMNWHYAEKDGKPTLVKPPH
VNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVTV
SLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYD
HRTIQGAASGEFLRIVANYLLGEAGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAAR
VFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSLMKL
RDILGVLRDSYCRTTGVEFMHIQDPKQRRWIQDRIERPHTKPEREEQLRILRRLNAAEAF
ETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGK
SYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVL
EGVARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVIN
NQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVI
DLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQ
GQLEKVFTEVREATSQPAAAAAQDPQDGFPVAVNTAITAETVKRIAESQVNVPDHITAHP
RLLPQLQRRASMVEDGTIDWGMGETLAVGSLLLEGTPVRLAGQDSQRGTFGQRHAVIIDR
ETGEEFTPLMYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFVNGA
QTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTS
PSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTSGQFRPVIGDSSVDPNAV
KKVVFCAGKVYYDLEAERQKRGVTDTAIIRIERLYPLPGAEVQAEVNKYPNAEKYLWTQE
EPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQLV
REVFEA
NT seq
3801 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacgcagaccaagcgggcaag
aaccccgctgccgcgttcggcccgaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcgccgctgccgcctcggctccggcgggtactgcggccgcgggggccgcagcaaccacc
acacccgcggcacccgccgccccggccgcccccgcggctccggcccagaccgctcccgcg
caggcggccccgaagcccgccgccgccgccccggtcccggccgccgcgaagcccgcggcc
gcgcccgcccagccggcggccgcggcgaagctccccggccgccccaaggccggcgaggtg
acggccgcccccgacggcccggagctgatcacgctgcgcggccccgccgccgcggtcgcg
aagaacatgaacgcctccctggagctgcccacggccacgtccgtgcgcgccgtcccggtg
aagctgctgttcgacaaccgcatcgtcatcaacaaccacctgaagcgcgcccggggcggg
aagatctccttcacgcacctgatcggctacgcgatggtgcaggccatcaagacgatgccg
tcgatgaactggcactacgcggagaaggacgggaagcccaccctcgtcaagccgccgcac
gtcaacttcggcctcgccatcgacctggtgaagcccaacggcgaccgccagctggtcgtc
gcgggcatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggac
atcgtccgccgcgcccgtgacggcaagctgacgatggacgacttcaccggtgtcacggtc
tccctgaccaaccccggcggcctcggcaccgtccactccgtgccccgcctgatgcccggc
cagtcggtcatcatgggcgtcggctccatggactacccggcggagttccagggcaccagc
caggacaccctgaacaagctcggtatctcgaaggtcatgacgctcacgtcgacctacgac
caccggaccatccagggcgccgcctccggcgagttcctccgcatcgtcgcgaactacctc
ctcggcgaggccggcttctacgacgacatcttcgaggccctgcgcatcccctacgagccg
gtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcacgaaggccgcccgc
gtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccg
ctggagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggcctcaccctg
tgggacctggagcgcgagttcgcggtcggcggcttctccggcaagtccctgatgaagctg
cgtgacatcctcggcgtcctgcgtgactcgtactgccgtacgaccggcgtcgagttcatg
cacatccaggacccgaagcagcgccgctggatccaggaccgtatcgagcgcccgcacacc
aagccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgcggcggaggccttc
gagaccttcctgcagacgaagtacgtcggccagaagcgcttctcgctcgaaggcggcgag
tcggtcatcccgctgctcgacgcggtcatcgacagcgcggcggagtcccgtctcgacgag
gtcgtcatcggcatggcccaccgcggccgcctgaacgtcctggcgaacatcgtcggcaag
tcgtacgcgcagatcttccgtgagttcgagggcaacctcgacccgaagtcgatgcacggc
tccggcgacgtgaagtaccacctgggcgccgagggcacgttcacgggcctggacggcgag
cagatcaaggtgtcgctggtcgcgaacccctcgcacctcgaagccgtcgaccccgtcctc
gaaggcgtcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtc
ctgccggtggccctgcacggcgacgcggccttcgcgggccagggcgtggtggccgagacc
ctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatcaac
aaccaggtcggcttcacggccgccccggagtcctcgcgttcctccatgtacgccacggac
gtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccggaggccgtg
gtccgtgtggcccgtctggccttcgagttccgccaggcgttcaacaaggacgtggtgatc
gacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccag
ccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtcc
ctcatcggtcgcggcgacatcaccctggaagaggccgagcaggccctgcaggactaccag
ggccagctggagaaggtcttcacggaggtccgcgaggccacgtcgcagccggccgccgcc
gccgcacaggacccgcaggacggcttcccggtcgcggtgaacaccgcgatcacggcggag
accgtcaagcgcatcgccgagtcccaggtcaacgtcccggaccacatcaccgcccacccg
cgtctgctgccgcagctgcagcgccgggcgtcgatggtcgaggacggcacgatcgactgg
ggcatgggcgagaccctcgcggtcggctccctcctcctggagggcacccccgtccggctg
gccggccaggactcccagcgcggcaccttcggccagcgtcacgcggtgatcatcgaccgc
gagacgggcgaggagttcacgccgctgatgtacctctccgaggaccaggcgcggctgaac
gtctacaactccctcctctccgagtacgcggcgatgggcttcgagtacggctactcgctg
gcccgtcccgagtccctcgtgatgtgggaggcccagttcggcgacttcgtcaacggcgcc
cagacggtcgtggacgagttcatctcgtcggcggagcagaagtggggccagacgagcggt
gtcacgctcctcctcccccacggctacgagggccagggcccggaccactcgtccgcccgc
ccggagcgcttcctccagctctgcgcgcagaacaacatgacggtcgcgatgccgacctcc
ccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctg
gtcgtcttcaccccgaagtcgatgctgcgcctcaaggccgccgcgtcgaaggcggaggag
ttcacgagcggccagttccgcccggtcatcggtgacagctcggtcgacccgaacgcggtc
aagaaggtcgtcttctgcgccggcaaggtctactacgacctggaggccgagcgccagaag
cgcggcgtcaccgacacggcgatcatccgcatcgagcggctgtacccgctgccgggcgcc
gaggtccaggcggaggtcaacaagtacccgaacgccgagaagtacctctggacgcaggag
gagccggcgaaccagggtgcctggccgttcatcgccctcaacctgatcgaccacctcgac
ctcgcggtcggcgcggacgtcccccacggcgagcgtctgcggcgcatctcccgcccgcac
ggctcgtcgccggcggtgggttccgcgaagcgccaccaggccgagcaggagcagttggtg
cgtgaggtgttcgaggcgtaa
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