Streptomyces griseoincarnatus: UBV09_22850
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Entry
UBV09_22850 CDS
T11026
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sgro Streptomyces griseoincarnatus
Pathway
sgro00020
Citrate cycle (TCA cycle)
sgro00630
Glyoxylate and dicarboxylate metabolism
sgro00785
Lipoic acid metabolism
sgro01100
Metabolic pathways
sgro01110
Biosynthesis of secondary metabolites
sgro01120
Microbial metabolism in diverse environments
sgro01200
Carbon metabolism
sgro01210
2-Oxocarboxylic acid metabolism
Module
sgro_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sgro_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sgro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
UBV09_22850
00630 Glyoxylate and dicarboxylate metabolism
UBV09_22850
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
UBV09_22850
Enzymes [BR:
sgro01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
UBV09_22850
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
UBV09_22850
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
UBV09_22850
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
UBV09_22850
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WPW21344
LinkDB
All DBs
Position
complement(4998412..5002200)
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AA seq
1262 aa
AA seq
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MSPQSPSNSSISTDTDQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAPASSAPAGDAAAGAAVTPTAPSQPAAPAKAQAPAQPAAPAPAAKAPAPAKAPAQPAKQ
AAPAAKPAPARKAEPAGEAKSGPEQVTLRGPSAAVAKNMDASLELPTATSVRAVPVKLLF
DNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNHAYAKVDGKPTLVKPEHINLG
LAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDDFTGVTVSLTN
PGGLGTVHSVPRLMPGQSVIMGVGAMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVI
QGAASGEFLRQVANLLLGENNFYDEIFEALRIPYEPVRWLKDIDASHDDDVTKAARVFDL
IHSYRVRGHVMADTDPLEYKVRKHPDLDIVEHGLTLWDLEREFAVGGFAGKSMMKLRDIL
GVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGHTKPEREEQLRILRRLNAAEAFETFL
QTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVVGMAHRGRLNVLANIVGKSYAQ
IFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVS
RAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVG
FTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLIC
YRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQGQLE
KVFTEVREATSQPATVAPSDPQAEFPVAVNTAVSTEVVKRIAESQVNIPDHITVHPRLLP
QLQRRASMVEDGTIDWGMGETLAFGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDRETGE
EYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFVNGAQTVV
DEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTSPSNY
FHLLRWQVHNPHHKPLVVFTPKSMLRLKAAAAKADEFTTGQFRPVIGDDTVDPAAVKKVV
FCAGKVYYDLAAEKKKRGADDTAIIRIERLYPLPGAELQAEIKKYPNAEKYLWAQEEPAN
QGAWPFIALNLIDHLDLAVGADLPHDERLRRISRPHSSSPAVGSAKRHQAEQEQLVREVF
EA
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcgggaaag
aaccccgctgcggccttcggtgccaacgaatggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtggaccgagcctggtgggacttcttcgccgactacaagccg
ggcgctcccgcgtcctcggctccggcgggtgacgcggccgcgggggccgcggtgaccccc
accgctccgtcccagccggccgcgcccgcgaaagcccaggcccccgctcagcccgccgcg
cccgccccggcggccaaggccccggccccggcgaaggccccggcccagccggcgaagcag
gccgcccccgccgccaagccggccccggccaggaaggccgagcccgcgggcgaggccaag
agcggtcccgagcaggtcaccctgcgcggcccgtccgccgcggtggcgaagaacatggac
gcgtcgctggagctgcccacggccacgtccgtgcgcgcggtcccggtgaagctgctgttc
gacaaccgcatcgtcatcaacaaccacctgaagcgcgcgcggggcgggaagatctccttc
acgcacctcatcggctacgccatggtccaggccatcaaggccatgccgtcgatgaaccac
gcgtacgccaaggtggacggcaagccgaccctggtgaagccggagcacatcaacctcggc
ctcgccatcgacctggtcaagccaaacggcgaccgccagctcgtcgtcgcggcgatcaag
aaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatcgtccgtcgc
gcccgcgacaacaagctgacgatggacgacttcaccggcgtcacggtctccctgaccaac
cccggcggcctcggcacggtccactccgtgccgcgtctgatgcccggacagtccgtgatc
atgggcgtcggcgccatggactacccggcggagttccagggcacctcccaggacaccctg
aacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtgatc
cagggcgccgcctccggcgagttcctgcgccaggtcgcgaacctcctgctcggcgagaac
aacttctacgacgagatcttcgaggccctgcgcatcccctacgagccggtccgctggctc
aaggacatcgacgccagccacgacgacgacgtcaccaaggccgcccgggtcttcgacctg
atccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctcgagtacaag
gtccgcaagcaccccgacctggacatcgtcgagcacggcctcaccctgtgggacctggag
cgcgagttcgccgtcggcggcttcgccggcaagtcgatgatgaagctgcgcgacatcctc
ggcgtgctccgcgactcgtactgccgcaccaccggcatcgagttcatgcacatccaggac
cccaagcagcgcaagtggatccaggaccgcgtcgagcgcggccacaccaagccggagcgc
gaggagcagctgcgcatcctgcgccggctgaacgcggcggaggccttcgagaccttcctg
cagaccaagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtcatcccg
ctgctcgacgcggtgctggactcggccgccgagtcccgtctggacgaggtcgtcgtcggc
atggcccaccgcggccgcctcaacgtcctcgccaacatcgtcggcaagtcgtacgcgcag
atcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtg
aagtaccacctgggcgccgagggcacgttcaccggcctggacggcgagcagatcaaggtc
tcgctggtcgccaacccctcgcacctggaggcggtcgacccggtcctggagggcgtctcc
cgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctgccggtggcc
atccacggcgacgcggccttcgcgggccagggcgtggtggccgagaccctgaacatgtcg
cagctgcgcggctaccgcaccggcggcaccgtgcacgtcgtcatcaacaaccaggtcggc
ttcaccgcggcccccgagtcctcgcgctcctccatgtacgcgacggacgtggcccgcatg
atcgaggccccgatcttccacgtgaacggcgacgacccggaggcggtcgtgcgcgtcgcg
cgcctggccttcgagttccgccaggcgttcaacaaggacgtggtgatcgacctcatctgc
taccgccgccgtggtcacaacgagtcggacaacccggccttcacccagccgctgatgtac
gacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgagtccctcatcggtcgc
ggcgacatcaccctggaagaggccgagcaggcgctccaggactaccagggccagctggag
aaggtcttcaccgaggtccgtgaggccacctcgcagccggccacggtcgccccgtccgac
ccgcaggccgagttcccggtcgccgtgaacaccgcggtgagcacggaggtcgtgaagcgg
atcgccgagtcgcaggtgaacatccccgaccacatcaccgtccacccgcgtctgctgccg
cagctgcagcgccgcgcgtcgatggtcgaggacggcaccatcgactggggcatgggcgag
accctcgccttcggctcgctgctgctggagggcgtaccggtccggctcgccggccaggac
tcgcagcgcggcaccttcggccagcgtcacgcggtcatcatcgaccgtgagacgggcgag
gagtacacgccgctgcagtacctctccgaggaccaggcgcggctgaacgtctacaactcc
ctgctgtccgagtacgcggccatgggcttcgagtacggctactcgctggcccggccggac
gcgctcgtgctctgggaggcgcagttcggcgacttcgtcaacggcgcgcagacggtcgtg
gacgagttcatctcgtcggccgaacagaagtgggcccagacctccggtgtggtcctgctc
ctcccccacggctacgaggggcagggcccggaccactcctcggcccgcccggagcgcttc
ctgcagctctgcgcccagaacaacatgacggtcgccatgccgacctcgccgtcgaactac
ttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtggtcttcacc
ccgaagtcgatgctgcgcctcaaggccgccgcggcgaaggcggacgagttcacgacgggc
cagttccgcccggtcatcggcgacgacacggtcgacccggccgccgtgaagaaggtcgtc
ttctgcgccggcaaggtgtactacgacctggccgccgagaagaagaagcgcggcgcggac
gacacggcgatcatccgcatcgagcgcctgtacccgctgccgggtgccgagctccaggcg
gagatcaagaagtacccgaacgccgagaagtacctgtgggcgcaggaggagccggcgaac
cagggtgcctggccgttcatcgcgctcaacctgatcgaccacctggacctggcggtcggc
gccgacctgccgcacgacgagcgtctgcgccgcatctcgcggccgcacagctcgtcgccg
gcggtcggctccgccaagcgccaccaggccgagcaggagcagctggtgcgcgaggtcttc
gaggcctga
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