Streptomyces griseoaurantiacus: V9K83_10435
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Entry
V9K83_10435 CDS
T10677
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sgrs Streptomyces griseoaurantiacus
Pathway
sgrs00020
Citrate cycle (TCA cycle)
sgrs00630
Glyoxylate and dicarboxylate metabolism
sgrs00785
Lipoic acid metabolism
sgrs01100
Metabolic pathways
sgrs01110
Biosynthesis of secondary metabolites
sgrs01120
Microbial metabolism in diverse environments
sgrs01200
Carbon metabolism
sgrs01210
2-Oxocarboxylic acid metabolism
Module
sgrs_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sgrs_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sgrs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
V9K83_10435
00630 Glyoxylate and dicarboxylate metabolism
V9K83_10435
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
V9K83_10435
Enzymes [BR:
sgrs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
V9K83_10435
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
V9K83_10435
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
V9K83_10435
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
V9K83_10435
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WWY84595
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All DBs
Position
2456315..2460124
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AA seq
1269 aa
AA seq
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MSPQSPSNSSISTETDQAGKNPAASFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAASAPASAGDAAAGAARTTTAPTQAAPAQPAAPAQRAAQPAAAAPAQPARPAAAPAAAP
AEQAAKPAAAPKAAPAAAKATSATEAPQGPEYVTLRGPSAAVAKNMNASLEMPTATSVRA
VPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWHYAEKDGKPTLVK
PEHVTFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRAREGKLTMEDFSG
VTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTS
TYDHRVIQGAASGEFLRIVANLLLGENEFYDEIFKALRIPYEPVRWLKDIDASHDDDVTK
AARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSL
MKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERPHSKPEREEQLRILRRLNAA
EAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANI
VGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIRVSLAANPSHLETVD
PVIEGITRAKQDIINKGGTDFTVMPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHI
VINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKD
VVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQ
DYQGQLEKVFTEVREATAQPAAPHSPDPQAEFPVAVSTAISTEVVKRIAESQVNIPDHFT
VHPRLLPQLQRRASMVEDGTIDWGMGETLAIGSLLLEGTPVRLSGQDSRRGTFGQRHAVL
IDRETGEDYTPLLYLSQDQARYNVYDSLLSEYAVMGFEYGYSLARPESLVMWEAQFGDFV
NGAQSVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAQ
PTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDDTVDP
AAVKKVVFCAGKVYYDLAAERKKRGANDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLW
TQEEPANQGAWPFIALNLIDHLDLAVGADIPHSERLRRISRPHSSSPAVGSAKRHQAEQE
QLVREVFEA
NT seq
3810 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctccaccgagaccgaccaagccgggaag
aaccccgcggcctcgttcggggccaatgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgcgcctggtgggacttcttcgcggactacaagccc
ggagcggcctccgccccggcttcggcgggtgacgcggccgcgggggccgcgcgcaccacc
accgctcccacccaggccgcccctgcgcagcccgcggccccggcccagcgcgccgcgcag
ccggccgccgccgcgcccgcgcagcccgcccggcccgcggccgcacccgccgccgcaccg
gccgagcaggccgcgaagcccgccgccgccccgaaggccgctcccgcggccgccaaggcg
acgtcggccaccgaggccccccagggccccgagtacgtgacgctgcgcggtccctccgcg
gccgtggcgaagaacatgaacgcctcgctggagatgcccacggccacgtccgtgcgcgcg
gtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctcaagcgggcc
cggggcgggaagatctccttcacccacctcatcggctacgcgatggtgcaggccatcaag
gccatgccgtcgatgaactggcactacgcggagaaggacggcaagccgaccctcgtcaag
ccggagcacgtcaccttcggcctggccatcgacctggtgaagcccaacggcgaccgccag
ctcgtcgtcgccggcatcaagaaggccgagacgctgaacttcttcgagttctggcaggcc
tacgaggacatcgtccgccgcgcccgtgagggcaagctgacgatggaggacttcagcggc
gtcacggtctccctgaccaaccccggcggcctgggcaccgtccactccgtgccgcgcctg
atgcccggccagtcggtcatcatgggcgtcggctccatggactacccggccgagttccag
ggcacctcccaggacaccctgaacaagctgggcatctccaaggtgatgaccctcacctcc
acgtacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcggatcgtcgcc
aacctgctgctcggcgagaacgagttctacgacgagatcttcaaggcgctgcgcatcccc
tacgagccggtccgctggctcaaggacatcgacgccagccacgacgacgacgtcaccaag
gccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgac
accgacccgctggagtaccagcagcgcaagcaccccgacctggacatcaccgagcacggg
ctcaccctgtgggacctggagcgcgagttcgcggtcggcggtttcgcgggcaagtccctg
atgaagctgcgcgacatcctgggcgtgctgcgtgactcgtactgccgcaccaccggcatc
gagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcatcgagcgc
ccgcacagcaagcccgagcgcgaggagcagctccgcatcctgcgccgcctcaacgcggcg
gaggccttcgagaccttcctgcagacgaagtacgtcggccagaagcggttctccctggag
ggcggcgagtccgtcatcccgctgctcgacgccgtgctggactcggccgccgagtcgcgc
ctggacgaggtcgtcatcggcatggcccaccgcggccggctgaacgtgctggcgaacatc
gtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcg
atgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggtctc
gacggcgagcagatccgcgtctcgctggccgccaacccctcccacctggagacggtcgac
ccggtcatcgagggcatcacccgcgccaagcaggacatcatcaacaagggcggcaccgac
ttcacggtcatgccggtggcgatccacggcgacgcggccttcgcgggccagggcgtcgtg
gccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatc
gtcatcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgttcctcgatgtac
gcgacggacgtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccg
gaggccgtcgtgcgcgtggcgcggctcgccttcgagttccgccaggcgttcaacaaggac
gtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggcc
ttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctac
accgagtccctcatcggtcgcggtgacatcaccctggaagaggccgagcaggcgctgcag
gactaccagggccagctggagaaggtcttcacggaggtccgcgaggccaccgcgcagccc
gccgccccgcactcgccggacccgcaggccgagttcccggtcgccgtcagcaccgcgatc
tccacggaggtcgtcaagcggatcgccgagtcccaggtcaacatccccgaccacttcacc
gtccacccgcggctgctcccgcagctccagcgccgggcgtcgatggtcgaggacggcacg
atcgactggggcatgggcgagaccctggccatcggctcgctgctgctggagggcaccccg
gtccggctgtccggacaggactcccgccgcggcaccttcggccagcgccacgcggtgctg
atcgaccgcgagaccggcgaggactacaccccgctgctgtacctgtcgcaggaccaggcc
cgctacaacgtctacgactcgctgctctccgagtacgcggtgatgggcttcgagtacggc
tactcgctcgcccgtccggagtcgctggtgatgtgggaggcgcagttcggcgacttcgtc
aacggcgcccagtcggtggtcgacgagtacatctcggccgccgagcagaagtggggccag
acctccggcgtcacgctgctgctgccgcacggctacgagggccagggcccggaccactcc
tcggcccgcatcgagcggttcctgcagctctgcgcgcagaacaacatgacggtcgcccag
ccgacctcgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccac
aagccgctggtcgtcttcaccccgaagtcgatgctccgcctgaaggcggcggcctcgaag
gcggaggagttcaccaccggccagttccgcccggtcatcggcgacgacacggtcgacccg
gccgccgtcaagaaggtcgtcttctgcgcgggcaaggtctactacgacctcgccgccgag
cggaagaagcgcggcgcgaacgacacggccatcatccgcatcgagcgcctgtacccgctg
ccgggtgccgagctccaggcggagatcgccaagtacccgaacgccgagaagtacctgtgg
acgcaggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgac
cacctggacctggcggtcggcgcggacatcccgcacagcgagcgcctgcgccgcatctcc
cggccgcactcctcctcccccgccgtgggttccgcgaagcggcaccaggcggagcaggag
cagctcgtccgcgaggtgttcgaggcgtaa
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