Streptomyces glaucescens: SGLAU_09970
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Entry
SGLAU_09970 CDS
T03327
Symbol
aceE1
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu00010
Glycolysis / Gluconeogenesis
sgu00020
Citrate cycle (TCA cycle)
sgu00620
Pyruvate metabolism
sgu00785
Lipoic acid metabolism
sgu01100
Metabolic pathways
sgu01110
Biosynthesis of secondary metabolites
sgu01120
Microbial metabolism in diverse environments
sgu01200
Carbon metabolism
sgu01210
2-Oxocarboxylic acid metabolism
Module
sgu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SGLAU_09970 (aceE1)
00020 Citrate cycle (TCA cycle)
SGLAU_09970 (aceE1)
00620 Pyruvate metabolism
SGLAU_09970 (aceE1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SGLAU_09970 (aceE1)
Enzymes [BR:
sgu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SGLAU_09970 (aceE1)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
AIR98004
UniProt:
A0A089XA57
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Position
2268996..2271698
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AA seq
900 aa
AA seq
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MTDPNAIQPSALDQLPDRDPEETAEWQASLDAVAKAAGPHRAAYLMRRTLERAEGAGIAL
PKLLETDYVNTIPTAAEPAVPGDEAMEARITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFKGKEADGSGDQLYIQGHASPGIYARAFLDGRLNEAHLDNFRRESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDVSDSHVWAFLGDGEM
DEPESTAALALAAREELDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVIKTL
WGSAWDELFRLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGKDPALAEMAKLLSD
DKILEIFHFSRGGHEPRKVYAAYKAAVEHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLSVDEFKAMRDLLDLPIKDSDFVDGVVPYGHPGADSPEVRYLKERRAALGGPAPARRVH
PLPALPAPAEKAFTSFDKGSGSQNVATTMAFVRLIKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEARNGQILNEGITEAGSMADFIAASTSYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAVIVREGLRRMYGEAKPGEDQDVFYYLTVYNEPLPQPAKPQ
GLGIDEGIVKGLYRFNTAESAGVEVAAGAPRIQLLGSGTAIHWALQAQKLLAEEWGVAAD
VWSATSWSELRRDALEADEALLRGEERVPFVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTREAARRHFGVDAQSIVVAALAQLARRGEVKATAVKEARERYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgcgctcgaccagctccccgaccgcgacccc
gaggagaccgccgaatggcaggcctcgctggacgcggtcgccaaggcggccggcccgcac
cgtgccgcgtacctgatgcggcgcacgctggagcgcgccgagggcgccggcatcgcgctg
ccgaagctcctcgagacggactacgtcaacaccatccccaccgccgccgaacccgccgtg
ccgggtgacgaggcgatggaggcccggatcaccgcctggaaccgctggaacgcggcggcc
atggtgacccgcggctcgaagtacggcgtcggcggccacatcgccaccttcgcctccgcg
gcgtggctgtacgagaccggcttcaaccacttcttcaagggcaaggaggccgacggctcg
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggctgaacgaggcccacctcgacaacttccgccgcgagtccggcggcaacggc
ctgccgtcctacccccacccgcgccgcctgccctggctgtgggagttccccaccgtctcc
atgggcctcggcccgctctccgcgatctaccaggcgcgcttcaaccgctacctgaccaac
cgcggcatcaaggacgtctccgactcccacgtgtgggccttcctcggcgacggcgagatg
gacgagccggagtcgacggcggcgctcgcgctcgccgcgcgtgaggagctggacaacctc
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcatcaagacgctg
tggggctccgcctgggacgagctgttccggctcgacaccaccggcgcgctggtacgccgg
ctgcgcgaggtaccggacgcgcaggtccagacgtaccagacccgcgacgccgcctacatc
cgccaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctgagcgac
gacaagatcctggagatcttccacttctcccgcggcggtcacgagccgcgcaaggtctac
gccgcgtacaaggccgccgtcgagcacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctctcggtggacgagttcaaggcgatgcgcgacctgctcgacctgccgatcaaggac
agcgacttcgtcgacggcgtggtgccctacggccacccgggcgccgactcccccgaggtc
cgctacctcaaggagcgccgcgccgccctcggcggtccggccccggcccgccgcgtgcac
ccgctgcccgcgctgcccgcccccgcggagaaggcgttcacctccttcgacaagggctcc
ggctcccagaacgtcgccaccaccatggccttcgtccgcctgatcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggt
atggagtcgctcttcccgtcgctcggcatctactcgcccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggcccggaacggccagatcctcaacgag
gggatcaccgaggccggctcgatggccgacttcatcgccgcttcgacgtcgtacgcgacg
cacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacc
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggcgccacc
gccggccgcaccacgctgaccggtgagggcctgcagcacgccgacggccactcccccgtc
atcgccgcgaccaacccggccgcgctcacctacgatcccgcgttcgcctacgaggtcgcg
gtgatcgtccgtgagggtctgcgccggatgtacggcgaggccaagccgggcgaggaccag
gacgtcttctactacctcacggtctacaacgagccgctgccgcagccggccaagccgcag
ggcctcggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcg
gcgggcgtcgaggtggcggcgggcgctccgcgcatccagctgctgggctccggcaccgcc
atccactgggcgctgcaggcgcagaagctgctcgccgaggagtggggcgtcgcggcggac
gtctggtccgccacctcctggtcggagctgcgccgggacgcgctggaggccgacgaggcg
ctgctgcgcggcgaggagcgggtgccgttcgtccgccaggcgctgcagggcgccgagggc
ccggtgctggcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactggtcctcgctgggcgccgacggcttcggcctgtcggacacccgtgaggcc
gcccgccgccacttcggcgtcgacgcccagtcgatcgtcgtcgcggccctggcccagctc
gcccggcgcggcgaggtcaaggcgacggccgtgaaggaggcgcgcgagcgctacggcctg
taa
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