Streptomyces glaucescens: SGLAU_10900
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Entry
SGLAU_10900 CDS
T03327
Symbol
aceE2
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu00010
Glycolysis / Gluconeogenesis
sgu00020
Citrate cycle (TCA cycle)
sgu00620
Pyruvate metabolism
sgu00785
Lipoic acid metabolism
sgu01100
Metabolic pathways
sgu01110
Biosynthesis of secondary metabolites
sgu01120
Microbial metabolism in diverse environments
sgu01200
Carbon metabolism
sgu01210
2-Oxocarboxylic acid metabolism
Module
sgu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SGLAU_10900 (aceE2)
00020 Citrate cycle (TCA cycle)
SGLAU_10900 (aceE2)
00620 Pyruvate metabolism
SGLAU_10900 (aceE2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SGLAU_10900 (aceE2)
Enzymes [BR:
sgu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SGLAU_10900 (aceE2)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AIR98184
UniProt:
A0A089XAJ9
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Position
2490464..2493211
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETREWLDSLDAAIDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERRILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAYLLDRLSEQHLDGFRQ
EKSRAPYGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMHARGIADTSRSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKVIQELESVFRGA
GWNVIKLIWDRSWDPLLAQDRDGILVNKMNTTPDGQFQTYATESGAYIREHFFGDDQRLR
AMVANMTDDQILHLGRGGHDHRKIFAAFSAAKAHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPIPDKELESGLPPYYHPGRDSEEIQYMHDRRRSLGGYVP
TRVVRSKPLTLPGDQTYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIVKDGLRRMYGGSQEHPHGEDVFYYLTVYNEPIQH
PAEPADVDVEGILKGLYRFSEGTSGEIPAQIMASGVAVPWAVEAQRLLAEEWNVRADVWS
ATSWNELRRDAVACEEHNLLHPDEEQRVPYVTRKLSGAQGPFVAVSDWMRAVPDQISRWV
PGAYQSLGADGFGFADTRGAARRFFHIDAQSIVLAVLAELAKAGKVDRSVLKQAMDRYQL
LDVAAADPGVAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaatccgatcatcattggcggccttccgagtcaggttcct
gacttcgaccccgaggagacgcgggagtggctcgattcgctcgacgccgccatcgacgag
cggggccgtgagcgcgcccgctacctgatgctccggctgatcgagcgggcccgcgagaag
cgcgtggccgtgccggagatgcgcagcacggactacgtcaacaccatcgccaccaaggac
gagccgttcttcccgggcaacgaggagatcgagcgcaggatcctcaacgccacccgctgg
aacgccgccgtgatggtctcccgcgcccagcgcccgggcatcggcgtcggcggccacatc
gccacgttcgcctcctccgcgtccctgtacgacgtgggcttcaaccacttcttccggggc
aaggacgagggggacggcggcgaccaggtcttcttccagggacacgcctcgccgggcatc
tacgcgcgcgcctacctgctggaccggctctccgaacagcacctcgacggcttccgccag
gagaagtcgcgggcgccgtacgggctgtcctcgtacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtgtccatgggcctcggcccgatcggcgcgatctaccaggcc
cggatgaaccggtacatgcacgcgcgcggcatcgcggacacctccaggtcgcacgtctgg
gcgttcctcggggacggcgagatggacgagccggagtcgctcggccagctcagcatcgcc
gcccgggagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcggctcgac
ggcccggtgcgcggcaacggcaaggtcatccaggagctggagtcggtcttccggggtgcc
ggctggaacgtgatcaagctgatctgggaccggtcgtgggacccgctgctcgcgcaggac
cgggacggcatcctcgtcaacaagatgaacaccacgccggacggccagttccagacgtac
gccaccgagtccggcgcgtacatccgcgagcacttcttcggcgacgaccagcggctgcgc
gccatggtcgcgaacatgaccgacgaccagatcctgcacctggggcgcggcggccacgac
caccggaagatcttcgcggcgttctcggcggccaaggcgcacaagggccagccgacggtg
atcctggccaagacgatcaagggctggacgctgggcccgaacttcgagggccgcaacgcc
acccaccagatgaagaagctgacggtcgacgacctcaagcgcttccgggaccggctgcac
ctgccgatcccggacaaggagctggagagcggtctcccgccgtactaccaccccgggcgg
gactccgaggagatccagtacatgcacgaccggcgcaggtcgctgggcgggtacgtgccg
acgcgggtcgtccggtcgaagccgctgacgctgcccggcgaccagacctacgcgaccgtg
aagaagggctccggtcagcagtccatcgccacgaccatggcctttgtgcgcctgctgaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcgccggacgagtac
cgcacgttcggcatggactcgttcttcccgagtgcgaagatctacaacccgctgggacag
cagtacgaggcggtcgaccgcgatctgctgctcgcctacaaggagtcgcccaccggccag
atgctgcacgacggcatctcggaggccggctgcaccgcgtcgctgatcgctgcgggctcg
gcgtacgccacccacggcgagccgctgatcccggtctacgtcttctactcgatgttcggt
ttccagcgcaccggcgaccagttctggcagatggccgaccagctggcgcgcggcttcgtc
ctgggcgcgaccgccgggcgcaccaccctgaccggtgaggggctccagcacgcggacggc
cactcccagctgctcgcctccacgaacccgggctgcgtcgcgtacgaccccgccttcggg
ttcgagatcgcgcacatcgtcaaggacgggctgcggcggatgtacggcggcagccaggag
cacccgcacggcgaggacgtcttctactacctgaccgtctacaacgagccgatccagcac
ccggcagagccggccgacgtcgacgtcgagggcatcctcaagggcctctaccggttcagc
gagggcacgtccggcgagatcccggcgcagatcatggcgtccggcgtggccgtcccctgg
gcggtcgaggcgcagcggctcctcgccgaggagtggaacgtacgggccgacgtgtggtcc
gcgacctcctggaacgagctgcggcgggacgcggtggcctgcgaggagcacaatctgctg
caccccgacgaggagcagcgggtgccgtacgtcacccggaagctgtccggcgcgcaggga
ccgttcgtggccgtctcggactggatgcgcgcggttcccgaccagatctcgcggtgggtg
cccggggcgtaccagtcgctcggcgcggacgggttcggcttcgccgacacccggggcgcg
gcccgccgcttcttccacatcgacgcccagtcgatcgtgctcgcggtgctcgccgagctg
gcgaaggcggggaaggtggaccggtcggtgctgaagcaggccatggaccggtaccagctg
ctcgacgtcgcggcggcggacccgggggtcgcgggcggcgacgcctga
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