Streptomyces glaucescens: SGLAU_26355
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Entry
SGLAU_26355 CDS
T03327
Symbol
tcmK
Name
(GenBank) Tetracenomycin C polyketide putative beta-ketoacyl synthase 1
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu00253
Tetracycline biosynthesis
sgu01056
Biosynthesis of type II polyketide backbone
sgu01100
Metabolic pathways
sgu01110
Biosynthesis of secondary metabolites
Module
sgu_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
SGLAU_26355 (tcmK)
00253 Tetracycline biosynthesis
SGLAU_26355 (tcmK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
sgu01004
]
SGLAU_26355 (tcmK)
01008 Polyketide biosynthesis proteins [BR:
sgu01008
]
SGLAU_26355 (tcmK)
Enzymes [BR:
sgu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
SGLAU_26355 (tcmK)
2.3.1.260 tetracycline polyketide synthase
SGLAU_26355 (tcmK)
Lipid biosynthesis proteins [BR:
sgu01004
]
Polyketide synthase
Component type
SGLAU_26355 (tcmK)
Polyketide biosynthesis proteins [BR:
sgu01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
SGLAU_26355 (tcmK)
Nonaketide PKS
SGLAU_26355 (tcmK)
Decaketide PKS
SGLAU_26355 (tcmK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_N
Acyl-CoA_dh_1
Motif
Other DBs
NCBI-ProteinID:
AIS01209
UniProt:
A0A089XD62
LinkDB
All DBs
Position
6012056..6013336
Genome browser
AA seq
426 aa
AA seq
DB search
MTRHAEKRVVITGIGVRAPGGAGTAAFWDLLTAGRTATRTISLFDAAPYRSRIAGEIDFD
PIGEGLSPRQASTYDRATQLAVVCAREALKDSGLDPAAVNPERIGVSIGTAVGCTTGLDR
EYARVSEGGSRWLVDHTLAVEQLFDYFVPTSICREVAWEAGAEGPVTVVSTGCTSGLDAV
GYGTELIRDGRADVVVCGATDAPISPITVACFDAIKATSANNDDPAHASRPFDRNRDGFV
LGEGSAVFVLEELSAARRRGAHAYAEVRGFATRSNAFHMTGLKPDGREMAEAITAALDQA
RRTGDDLHYINAHGSGTRQNDRHETAAFKRSLGQRAYDVPVSSIKSMIGHSLGAIGSLEL
AACALAIEHGVIPPTANYEEPDPECDLDYVPNVAREQRVDTVLSVGSGFGGFQSAAVLAR
PKETRS
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atgacccggcacgcggagaagcgggtggtgatcaccggcatcggtgtgcgagccccggga
ggcgccggaaccgcggccttctgggacctgctcaccgccggacgcaccgccaccaggacg
atctccctgttcgacgccgcgccctaccggtcccggatagccggagagatcgacttcgac
ccgatcggcgagggcctgtcgccccggcaggcgtcgacgtacgaccgggccacgcagctc
gccgtcgtctgcgcccgcgaggcgctgaaggacagcgggctggacccggccgcggtgaac
ccggaacggatcggggtgagcatcggcaccgccgtcggctgcaccaccggcctcgaccgc
gagtacgcgcgggtcagcgagggcggctcgcgctggctggtcgaccacacgctcgcggtg
gagcagctcttcgactacttcgtcccgacctccatctgccgggaggtcgcctgggaggcg
ggggccgagggaccggtgacggtggtgtcgaccgggtgcacctcgggcctcgacgccgtc
ggatacggcacggagctcatccgggacgggcgcgccgacgtggtcgtctgcggcgccacc
gacgcgccgatctcccccatcaccgtggcctgcttcgacgccatcaaggcgacgtcggcc
aacaacgacgacccggcccacgcctcccgccccttcgaccgcaaccgcgacggcttcgtg
ctcggggagggctcggcggtcttcgtcctggaggagctgtccgccgcccgccggcgagga
gcgcacgcctacgcggaggtccgcggcttcgccacacggtcgaacgccttccacatgacc
ggtctgaagccggacggcagggagatggcggaggccatcaccgccgccctggaccaggcc
cgccgcaccggcgacgacctgcactacatcaacgcgcacggctccggcacccggcagaac
gaccggcacgagacggcggccttcaagcgcagcctggggcaacgggcgtacgacgtgccc
gtcagctccatcaagtccatgatcggccactcgctcggagcgatcggctccctcgaactg
gccgcctgcgcgctggcgatcgaacacggcgtgatcccgcccaccgccaactacgaggaa
cccgaccccgaatgcgacctcgactacgtgccgaacgtcgcgcgggaacagcgggtcgac
accgtgctcagcgtcggcagcggattcggcggcttccagagcgccgcggtgctggcccgg
ccgaaggagacccgctcatga
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