Streptomyces gilvosporeus: B1H19_12820
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Entry
B1H19_12820 CDS
T05165
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgv
Streptomyces gilvosporeus
Pathway
sgv00010
Glycolysis / Gluconeogenesis
sgv00020
Citrate cycle (TCA cycle)
sgv00620
Pyruvate metabolism
sgv00785
Lipoic acid metabolism
sgv01100
Metabolic pathways
sgv01110
Biosynthesis of secondary metabolites
sgv01120
Microbial metabolism in diverse environments
sgv01200
Carbon metabolism
sgv01210
2-Oxocarboxylic acid metabolism
Module
sgv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
B1H19_12820
00020 Citrate cycle (TCA cycle)
B1H19_12820
00620 Pyruvate metabolism
B1H19_12820
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
B1H19_12820
Enzymes [BR:
sgv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
B1H19_12820
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Motif
Other DBs
NCBI-ProteinID:
ARF54977
UniProt:
A0A1V0TPV1
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Position
2924232..2926919
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AA seq
895 aa
AA seq
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MPDPVYGVMAQATRLPYSQLDQLPDRDPEETAEWRESLDAVTKAAGPHRAAYLMRRALEH
NGAPGLAPLETDYVNTIPTSAEPAFPGDEAMEARITAWNRWNAAAMVTRGSRFGVGGHIA
TFASAAWLYETGFQHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTEDHLDHFRQE
SGGKGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLQGRGIKDTANSHVWAFL
GDGEMDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRAAGWN
VVKSLWGSAWDELFQLDTTGALVRRLRLVPDAQFQTYATRDVAYIREHFFGAEPALVEMA
KVLTDAKIAECFHTSRGGHEARKVYAAYKAAVGFKGAPTVILAQTVKGYTLGPGFESKNA
NHQMKKLSGKEFRAMRDLLDLPIPDAKLDEDLVPYGHPGADSPEVRYLQERRAALGGPAP
ARRLHASAALPQPEERAFKALYKGSGKQEMATTMAFVRLVKDLMRDKETGRRWVPIVPDE
ARTFGMESLFPSAGIYSPKGQTYEPVDRDQLMYYKEATDGQILNEGITEAGAMADFIAAA
TSYATHGEPMIPFYIFYSMFGWQRTADQMWQLADQLGKGFIVGATAGRTTLTGEGLQHAD
GHSHLIASTNPASLNYDPAFAYEIAVIVKDGLRRMYGETPEDVFYYLTVYNEPKQQPAMP
EGVEEGILKGLYRFKEAADATSETPRTQLLASGTAIHWALEAQRLLAEDWDVAADVWSAT
SWGELRRDALECDAARLEGEDRIPYVTRALAGAPGPVVAVSDWMRAVPDQIAPWVEQDWT
SIGTDGFGLSDTRDAARRHFGVDPQSVVVQTLAALARRGEVKPETVKEARQRYGL
NT seq
2688 nt
NT seq
+upstream
nt +downstream
nt
atgcccgaccccgtctacggagtaatggcgcaagccacacgcctgccgtacagccagctc
gaccagctcccggaccgggaccccgaggagaccgccgagtggcgcgaatcccttgacgcc
gtcaccaaggccgcgggcccgcaccgcgccgcgtatctgatgcgccgcgcgctggagcac
aacggtgctcccgggctcgcgcccctggagacggactacgtcaacaccatcccgacctcc
gccgagccggccttccccggcgacgaggcgatggaggcccggatcaccgcctggaaccgc
tggaacgccgccgccatggtgacgcgcggctcgcggttcggcgtcggcggccacatcgcg
accttcgcgtccgcggcctggctgtacgagaccggcttccagcacttcttccgcggcaag
gagggcgacggcagcggcgaccagctctacatccagggccacgcctccccgggcatctac
gcccgcgccttcctcgacggccgcctcaccgaggaccacctcgaccacttccgccaggag
tccggcggcaagggcctgccctcctacccgcacccgcggcggctgccgtggctgtgggag
ttcccgaccgtctccatgggcctcggcccgctgtcggcgatctaccaggcccgtttcaac
cgctacctccagggccgcggcatcaaggacaccgccaactcgcacgtctgggccttcctg
ggcgacggcgagatggacgagcccgagtcgaccgccgcgctcgcgctggccggccgcgag
ggtctggacaacctgaccttcgtcatcaactgcaacctccagcgcctcgacggcccggtg
cgcgccaacttcaagatcgttcaggagctggaggcgcagttccgcgccgccggctggaac
gtcgtcaaatcgctgtggggttcggcctgggacgagctgttccagctcgacaccacgggc
gcgctggtccgccggctgcgcctggtgccggacgcgcagttccagacgtacgccacccgc
gacgtggcctacatccgcgagcacttcttcggcgccgagccggccctcgtcgagatggcg
aaggtcctgaccgacgcgaagatcgccgagtgcttccacacctcccgcggcggccacgag
gcccgcaaggtgtacgcggcgtacaaggcggccgtcgggttcaagggcgcgccgaccgtg
atcctcgcccagaccgtcaagggctacaccctcggccccggcttcgagtccaagaacgcc
aaccaccagatgaagaagctctcgggcaaggagttccgcgcgatgcgcgacctgctcgac
cttcccatcccggacgcgaagctggacgaggacctggtgccgtacggccacccgggagcc
gactcccccgaggtccgctacctccaggaacgccgcgccgcgctcggcggtccggccccg
gcccgccggctgcacgcctcggccgcgctgccgcagcccgaggagcgcgccttcaaggcg
ctgtacaagggctccggcaagcaggagatggccaccaccatggccttcgtccgcctggtc
aaggacctgatgcgggacaaggagaccggccgccgctgggtgccgatcgtcccggacgag
gcccgcaccttcggtatggagtcgctgttcccctcggccggcatctactcgccgaagggc
cagacgtacgagccggtcgaccgcgaccagctgatgtactacaaggaggccaccgacggc
cagatcctcaacgaggggatcaccgaggccggcgccatggccgacttcatcgccgccgcc
acgtcgtacgcgacccacggcgagccgatgatccccttctacatcttctactcgatgttc
ggctggcagcgcaccgccgaccagatgtggcagctcgccgaccagctcggcaagggcttc
atcgtcggcgccaccgcgggccgtacgaccctgaccggtgagggcctccagcacgccgac
ggccactcgcacctgatcgcgtccacgaacccggcgtcgctcaactacgacccggccttc
gcgtacgagatcgcggtgatcgtcaaggacggtctgcgccggatgtacggcgagaccccc
gaggacgtcttctactacctcaccgtctacaacgagcccaagcagcagccggccatgccc
gagggcgtcgaagagggcatcctcaagggcctctaccgcttcaaggaggccgccgacgcg
acgtcggagaccccgcgcacccagctgctggcctccggcaccgcgatccactgggccctg
gaggcacagcggctgctcgccgaggactgggacgtggccgccgacgtatggtccgcgacc
tcctggggcgagctgcgccgcgacgccctggagtgcgacgcggcccgcctggagggcgag
gaccgcatcccgtacgtcacccgtgccctggccggcgcccccggcccggtcgtcgcggtg
agcgactggatgcgggccgtcccggaccagatcgccccctgggtcgagcaggactggacg
tccatcggcaccgacggcttcggcctctccgacacccgcgatgcggcccgccgccacttc
ggcgtggacccgcagtcggtggtcgtccagacgctggccgccctggcccgccggggcgag
gtcaagccggagacggtcaaggaggcccggcagcgctacgggctgtga
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