Streptomyces gardneri: H4W23_12290
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Entry
H4W23_12290 CDS
T07252
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgx
Streptomyces gardneri
Pathway
sgx00010
Glycolysis / Gluconeogenesis
sgx00020
Citrate cycle (TCA cycle)
sgx00620
Pyruvate metabolism
sgx00785
Lipoic acid metabolism
sgx01100
Metabolic pathways
sgx01110
Biosynthesis of secondary metabolites
sgx01120
Microbial metabolism in diverse environments
sgx01200
Carbon metabolism
sgx01210
2-Oxocarboxylic acid metabolism
Module
sgx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
H4W23_12290 (aceE)
00020 Citrate cycle (TCA cycle)
H4W23_12290 (aceE)
00620 Pyruvate metabolism
H4W23_12290 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
H4W23_12290 (aceE)
Enzymes [BR:
sgx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
H4W23_12290 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
QPK45337
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Position
2722970..2725702
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AA seq
910 aa
AA seq
DB search
MAPGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATRDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAYLLDRLNDTQLDGFRQ
ERSKFPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSRSHVW
AFLGDGEMDEVESVGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGN
GWNVIKLIWDRSWDPLLAQDRDGILVNKFNTTPDGQFQTYATETGAYIREHFFGDDHRLR
AMVEGMSDKQVLHLGRGGHDHKKIYAAYAAAKAHAGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHIPVTDRQLEDGLPPYYHPGRNSEEIQYMHDRRSALGGYVP
TRVVRAKPLVLPDDTTYAAAKKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSHLLASTNPACIAYDPAFGFEIAHIVKDGLRRMYGPAAEDVFYYLTVYNEPIQHPAEPA
DVDVEGILAGIHRFKPAEAGSIPAQIMASGVAVPWAIEAQRILAEEWNVRADVWSATSWT
ELRREAVAVEEHNLLHPDEEQRVPYVTRKLHGAEGPFVAVSDWMRAVPDQISRWVPGTYT
SLGADGFGFADTRGAARRYFHIDAQSIVLSVLTELAREGKVDRSALKQAVDRYQLLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggctcccggatccgatcgcaacccgatcatcattggcggccttcccagccaggtcccg
gatttcgacccggaagagacccaggaatggctcgactccctcgacgcggccgtcgacgag
cggggccgtgagcgggcccgctacctcatgctccggctgatcgagcgggcgcgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacaccatcgccaccagggac
gagcccttcttccccggcaacgaggagatcgagcgcaaggtcctcaacgccacccggtgg
aacgcggccgtgatggtctcgcgcgcccagcgcccgggcatcggcgtcggcggtcacatc
gccaccttcgcctcctccgcctccctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccaggggcacgcctccccgggcatc
tacgcccgcgcgtacctcctggaccggctgaacgacacccagctcgacggcttccgccag
gagcggtcgaagttcccgaacgggctctcgtcgtacccgcatccccggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgctcggcgcgatctaccaggcg
cggatgaaccggtacatggaggcgcgcggcatcgccgacacctccaggtcgcacgtctgg
gcgttcctcggcgacggcgagatggacgaggtcgagtcggtcggccagctgtccatcgcc
gcccgtgagggcctggacaacctcaccttcgtcgtcaactgcaacctccagcggctcgac
ggcccggtgcgcggcaatggcaagatcatccaggagctggagtcgatcttccggggcaac
ggctggaacgtcatcaagctgatctgggaccgctcgtgggacccgctgctcgcgcaggac
cgcgacggcatcctggtgaacaagttcaacaccaccccggacggccagttccagacgtac
gcgacggagaccggcgcctacatccgcgagcacttcttcggcgacgaccaccggctgcgg
gccatggtcgagggcatgtcggacaagcaggtcctgcacctgggccgcggtggccacgac
cacaagaagatctacgcggcctacgcggcggcgaaggcgcacgccggccagccgaccgtg
atcctcgcccagaccgtcaagggctggacgctgggcccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccggctgcac
atcccggtgacggaccggcagttggaggacggcctgccgccctactaccaccccggccgg
aactccgaggagatccagtacatgcacgaccggcgcagcgcgctgggcgggtacgtgccg
acccgtgtcgtgcgggcgaagccgctggtcctccccgacgacacgacctacgcggcggcc
aagaagggttcgggccagcagtcgatcgccaccacgatggccttcgtccgcatcctgaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgctgatcgcccccgacgagtac
cgcaccttcggcatggacgccttcttcccgagcgccaagatctacaacccgctgggccag
cagtacgaggcggtggaccgcgaactcctcctcgcctacaaggagtcgccgaccggtcag
atgctgcacgacggcatctccgaggccggctgcacggcctcgctgatcgccgcgggctcg
gcctacgccacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggc
ttccagcggaccggcgatcagttctggcagatggccgaccagttggcgcgcggcttcgtg
ctcggcgccaccgccggccgtacgacgctgaccggcgagggcctccagcacgcggacggc
cactctcacctgctcgcctcgaccaacccggcctgtatcgcctacgacccggccttcggt
ttcgagatcgcgcacatcgtgaaggacggcctgcgccgcatgtacggcccggccgccgag
gacgtcttctactacctgaccgtctacaacgagccgatccagcacccggccgaaccggcg
gacgtggacgtcgagggcatcctcgccggtatccaccgcttcaagccggccgaggccggg
tcgatcccggcgcagatcatggcctccggtgtcgccgtgccgtgggcgatcgaggcgcag
cggatcctcgccgaggagtggaacgtacgcgccgacgtctggtccgcgacctcgtggacc
gagctgcgccgcgaggccgtggccgtcgaggagcacaatctgctccacccggacgaggag
cagcgcgtcccgtacgtgacgcgcaagctccacggcgccgagggcccgttcgtcgcggtc
tcggactggatgcgcgcggtcccggaccagatctcccgctgggtgccggggacgtacacc
tcgctgggcgcggacggcttcggcttcgcggacacgcggggtgcggcccgtcgctacttc
cacatcgacgcccagtcgatcgtgctgtcggtgctgaccgagctcgcccgcgagggcaag
gtcgaccggtcggccctgaagcaggccgtggaccgctaccagctgctcgacgtggcggcc
gccgaccccggcgccgcgggcggcgacgcctga
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