Streptomyces globosus: C0216_21690
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Entry
C0216_21690 CDS
T06864
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sgz
Streptomyces globosus
Pathway
sgz00270
Cysteine and methionine metabolism
sgz00450
Selenocompound metabolism
sgz00670
One carbon pool by folate
sgz01100
Metabolic pathways
sgz01110
Biosynthesis of secondary metabolites
sgz01230
Biosynthesis of amino acids
sgz04980
Cobalamin transport and metabolism
sgz04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
sgz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
C0216_21690 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
C0216_21690 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
C0216_21690 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
C0216_21690 (metH)
04980 Cobalamin transport and metabolism
C0216_21690 (metH)
Enzymes [BR:
sgz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
C0216_21690 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
CdhD
UPF0180
Motif
Other DBs
NCBI-ProteinID:
AXE25716
UniProt:
A0A344U495
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Position
complement(4892621..4896133)
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AA seq
1170 aa
AA seq
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MASLPNPPADTQNRADALREALATRVVVADGAMGTMLQAQEPSLEDFQQLEGCNEVLNVT
RPDIVRSVHDAYFAVGVDCVETNTFGANHSALGEYDIPERIHELSEAGARIAREAADAAT
AASGQQRWVLGSIGPGTKLPTLGHIVYATLRDAYQANAEGLIAGGSDALLVETTQDLLQT
KASVIGARRAMEALGVSVPLICSVTVETTGTMLLGSEIGAALTSLEPLGIDMIGLNCATG
PAEMSEHLRYLARNARIPLSCMPNAGLPVLGKDGAHYPLSAGELADAQETFVREYGLSLV
GGCCGTTPEHLRQVVERVRGLAPAVREPRPEPGASSLYQTVPFRQDTSYMAIGERTNANG
SKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMRELAARFATASTLP
VVLDSTEVDVIQAGLEALGGRAVINSVNYEDGDGPDSRFAKVTRLAQEHGAALIALTIDE
QGQARTVEHKVAIAERLIEDLTGNWGIHESDILIDCLTFTICTGQEESRKDGIATIEAIR
ELKRRHPEVQTTLGLSNISFGLNPAARVLLNSVFLDECVKAGLDSAIVHASKILPIARFD
DEQVSTALDLIYDRREGDYDPLQKLMALFEGVNTKSLKAGRAEELLALPLEERLRQRIVD
GEKNGLEADLDEALQTRPALDIVNDTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTAVA
YLEPHMEKSDAEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNIGIKQPVSAIVEA
AQEHRADVIGMSGLLVKSTVIMKENLEELNQRKLAATYPVILGGAALTRAYVEQDLHEIY
EGEVRYARDAFEGLRLMDALIAVKRGVPGAALPELKQRRVPRRDTPLPEAAEPEEPGGRS
DVSADNPVPTPPFWGTRVVKGIPLKDYASWLDEGALFKGQWGLKQARAGGPTYEELVETE
GRPRLRGLLEKLHTENLLEAAVVHGYFPCVSKGDDLIILDEAGNERTRFTFPRQRRGRRL
CLADFFRPEESGETDVVGLQVVTVGSRIGEATAKLFASDSYREYLELHGLSVQLAEALAE
YWHARVRAELGFGGEDPADVEDMFALKYRGARFSLGYGACPDLEDRAKIADLLRPERIGV
HLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3513 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgttgccgaacccgcccgccgacacccagaaccgggccgatgccctccgcgag
gcgctcgcgacccgcgtggtcgtcgccgacggggccatgggaacgatgctccaggcacag
gagccctccctggaggacttccagcagctcgaaggctgcaacgaggtcctcaacgtcacc
cgccccgacatcgtgcgctccgtccacgacgcctacttcgccgtcggcgtcgactgcgtc
gagaccaacaccttcggcgccaaccactccgcgctgggcgagtacgacatccccgagcgc
atccacgagctctccgaggccggcgcccgcatcgcccgcgaggccgccgacgccgccacc
gccgccagcgggcagcagcgctgggtgctgggctccatcggccccggcaccaagctgccg
accctgggccacatcgtgtacgccaccctccgcgacgcctaccaggccaacgcggagggc
ctgatcgccggcggctccgacgccctcctcgtcgagaccacccaggacctcctgcagacc
aaggcctcggtcatcggcgcccgccgcgccatggaggccctcggcgtctccgtcccgctc
atctgctccgtcaccgtggagacgaccggcaccatgctgctcggctccgagatcggcgcc
gcgctgacctccctggagccgctcggcatcgacatgatcggcctgaactgcgccaccggc
ccggccgagatgagcgagcacctgcgctacctcgcccgcaacgcccgcatccccctctcc
tgcatgccgaacgcgggcctgccggtcctcggcaaggacggcgcgcactacccgctgtcg
gcgggcgagctcgccgacgcccaggagaccttcgtccgcgagtacggcctctccctggtc
ggcggctgctgcggcaccacccccgagcacctgcggcaggtcgtcgagcgggtccgcggc
ctcgccccggccgtccgcgagccgcgccccgagccgggcgcctcctcgctgtaccagacc
gtgcccttccgccaggacacctcgtacatggcgatcggcgagcggaccaacgccaacggg
tcgaagaagttccgcgaggccatgctggaggcacgctgggacgactgcgtcgagatggcc
cgcgaccagatccgcgagggcgcgcacatgctcgacctgtgcgtggactacgtcggccgc
gacggcgtcgccgacatgcgcgagctggccgcccgtttcgcgaccgcctccaccctgccc
gtggtgctggactccaccgaggtcgacgtcatccaggccggcctggaggccctcggcggc
cgcgccgtcatcaactcggtcaactacgaggacggcgacggccccgactcccgcttcgcg
aaggtcacccgcctggcccaggagcacggcgcggccctgatcgccctcaccatcgacgag
cagggccaggcccgcaccgtcgaacacaaggtcgccatcgccgagcggctgatcgaggac
ctcaccggcaactggggcatccacgagtccgacatcctcatcgactgcctcaccttcacc
atctgcaccggccaggaggagtcccgcaaggacggcatcgccaccatcgaggccatccgc
gagctcaagcggcgccaccccgaggtgcagacgaccctgggcctgtcgaacatctccttc
ggcctcaacccggccgcccgcgtcctgctgaactccgtcttcctcgacgagtgcgtcaag
gccggccttgactcggcgatcgtccacgcctcgaagatcctgcccatcgcccgcttcgac
gacgagcaggtctccaccgccctcgacctcatctacgaccgccgcgagggcgactacgac
ccgctgcagaagctgatggccctcttcgagggcgtcaacaccaagtccctcaaggccggc
cgcgccgaggagctcctcgcgctgcccctggaggagcgcctgcggcagcgcatcgtcgac
ggcgagaagaacggcctggaggcggacctggacgaggccctgcagacccggcccgccctc
gacatcgtcaacgacaccctcctggagggcatgaaggtcgtcggcgagctcttcggatcc
ggccagatgcagctgccgttcgtcctccagtccgccgaggtcatgaagacggcggtggcc
tacctggagccgcacatggagaagtcggacgcggagggcaagggcaccatcgtcctggcc
accgtgcgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctctccaac
aacggctacaacgtcgtcaacatcggtatcaagcagccggtttcggcgatcgtggaggcc
gcgcaggagcaccgcgccgacgtcatcggcatgtccggcctgctcgtcaagtccaccgtg
atcatgaaggagaacctggaggagctgaaccagcgcaagctggccgccacctacccggtc
atcctcggcggcgccgccctcacccgcgcctacgtcgaacaggacctccacgagatctac
gagggcgaggtccgctacgcccgcgacgccttcgagggcctgcgcctgatggacgccctc
atcgccgtcaagcgcggcgtccccggcgccgccctgcccgagctcaagcagcgccgcgtc
cccaggcgcgacaccccgctgccggaggccgccgagccggaggagcccgggggccgctcg
gacgtctccgccgacaaccccgtcccgaccccgccgttctggggcacgcgggtcgtcaag
ggcatcccgctgaaggactacgcctcctggctcgacgagggcgccctcttcaagggccag
tggggcctgaagcaggcccgcgccggcggccccacctacgaggagctcgtcgagaccgag
ggccggccgcggctgcgcggcctgctggagaagctgcacaccgagaacctgctggaggcg
gccgtcgtccacggctacttcccgtgcgtctccaagggcgacgacctgatcatcctcgac
gaggccggcaacgagcggacccgcttcacctttccgcgccagcgccgcggccgccgcctg
tgcctcgcggacttcttccgccccgaggagtccggcgagaccgacgtcgtcggcctccag
gtcgtcaccgtcggctcgaggatcggcgaggccaccgccaagctgttcgcgtcggactcc
taccgcgagtacctggagctgcacggcctctccgtccagctcgccgaggccctcgccgag
tactggcacgcccgcgtccgcgccgagctcggcttcggcggcgaggaccccgccgacgtc
gaggacatgttcgccctgaagtaccggggcgcccgcttctccctcggctacggcgcctgc
cccgacctggaggaccgcgccaagatcgccgacctgctccggcccgagcggatcggcgtc
cacctgtcggaggagttccagctccacccggagcagtccaccgacgcgatcgtcatccac
caccccgaagcgaagtatttcaacgcacgctga
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