KEGG   Streptomyces globosus: C0216_21690
Entry
C0216_21690       CDS       T06864                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
sgz  Streptomyces globosus
Pathway
sgz00270  Cysteine and methionine metabolism
sgz00450  Selenocompound metabolism
sgz00670  One carbon pool by folate
sgz01100  Metabolic pathways
sgz01110  Biosynthesis of secondary metabolites
sgz01230  Biosynthesis of amino acids
sgz04980  Cobalamin transport and metabolism
sgz04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:sgz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    C0216_21690 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    C0216_21690 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    C0216_21690 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    C0216_21690 (metH)
   04980 Cobalamin transport and metabolism
    C0216_21690 (metH)
Enzymes [BR:sgz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     C0216_21690 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2 CdhD UPF0180
Other DBs
NCBI-ProteinID: AXE25716
UniProt: A0A344U495
LinkDB
Position
complement(4892621..4896133)
AA seq 1170 aa
MASLPNPPADTQNRADALREALATRVVVADGAMGTMLQAQEPSLEDFQQLEGCNEVLNVT
RPDIVRSVHDAYFAVGVDCVETNTFGANHSALGEYDIPERIHELSEAGARIAREAADAAT
AASGQQRWVLGSIGPGTKLPTLGHIVYATLRDAYQANAEGLIAGGSDALLVETTQDLLQT
KASVIGARRAMEALGVSVPLICSVTVETTGTMLLGSEIGAALTSLEPLGIDMIGLNCATG
PAEMSEHLRYLARNARIPLSCMPNAGLPVLGKDGAHYPLSAGELADAQETFVREYGLSLV
GGCCGTTPEHLRQVVERVRGLAPAVREPRPEPGASSLYQTVPFRQDTSYMAIGERTNANG
SKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMRELAARFATASTLP
VVLDSTEVDVIQAGLEALGGRAVINSVNYEDGDGPDSRFAKVTRLAQEHGAALIALTIDE
QGQARTVEHKVAIAERLIEDLTGNWGIHESDILIDCLTFTICTGQEESRKDGIATIEAIR
ELKRRHPEVQTTLGLSNISFGLNPAARVLLNSVFLDECVKAGLDSAIVHASKILPIARFD
DEQVSTALDLIYDRREGDYDPLQKLMALFEGVNTKSLKAGRAEELLALPLEERLRQRIVD
GEKNGLEADLDEALQTRPALDIVNDTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTAVA
YLEPHMEKSDAEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNIGIKQPVSAIVEA
AQEHRADVIGMSGLLVKSTVIMKENLEELNQRKLAATYPVILGGAALTRAYVEQDLHEIY
EGEVRYARDAFEGLRLMDALIAVKRGVPGAALPELKQRRVPRRDTPLPEAAEPEEPGGRS
DVSADNPVPTPPFWGTRVVKGIPLKDYASWLDEGALFKGQWGLKQARAGGPTYEELVETE
GRPRLRGLLEKLHTENLLEAAVVHGYFPCVSKGDDLIILDEAGNERTRFTFPRQRRGRRL
CLADFFRPEESGETDVVGLQVVTVGSRIGEATAKLFASDSYREYLELHGLSVQLAEALAE
YWHARVRAELGFGGEDPADVEDMFALKYRGARFSLGYGACPDLEDRAKIADLLRPERIGV
HLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggcctcgttgccgaacccgcccgccgacacccagaaccgggccgatgccctccgcgag
gcgctcgcgacccgcgtggtcgtcgccgacggggccatgggaacgatgctccaggcacag
gagccctccctggaggacttccagcagctcgaaggctgcaacgaggtcctcaacgtcacc
cgccccgacatcgtgcgctccgtccacgacgcctacttcgccgtcggcgtcgactgcgtc
gagaccaacaccttcggcgccaaccactccgcgctgggcgagtacgacatccccgagcgc
atccacgagctctccgaggccggcgcccgcatcgcccgcgaggccgccgacgccgccacc
gccgccagcgggcagcagcgctgggtgctgggctccatcggccccggcaccaagctgccg
accctgggccacatcgtgtacgccaccctccgcgacgcctaccaggccaacgcggagggc
ctgatcgccggcggctccgacgccctcctcgtcgagaccacccaggacctcctgcagacc
aaggcctcggtcatcggcgcccgccgcgccatggaggccctcggcgtctccgtcccgctc
atctgctccgtcaccgtggagacgaccggcaccatgctgctcggctccgagatcggcgcc
gcgctgacctccctggagccgctcggcatcgacatgatcggcctgaactgcgccaccggc
ccggccgagatgagcgagcacctgcgctacctcgcccgcaacgcccgcatccccctctcc
tgcatgccgaacgcgggcctgccggtcctcggcaaggacggcgcgcactacccgctgtcg
gcgggcgagctcgccgacgcccaggagaccttcgtccgcgagtacggcctctccctggtc
ggcggctgctgcggcaccacccccgagcacctgcggcaggtcgtcgagcgggtccgcggc
ctcgccccggccgtccgcgagccgcgccccgagccgggcgcctcctcgctgtaccagacc
gtgcccttccgccaggacacctcgtacatggcgatcggcgagcggaccaacgccaacggg
tcgaagaagttccgcgaggccatgctggaggcacgctgggacgactgcgtcgagatggcc
cgcgaccagatccgcgagggcgcgcacatgctcgacctgtgcgtggactacgtcggccgc
gacggcgtcgccgacatgcgcgagctggccgcccgtttcgcgaccgcctccaccctgccc
gtggtgctggactccaccgaggtcgacgtcatccaggccggcctggaggccctcggcggc
cgcgccgtcatcaactcggtcaactacgaggacggcgacggccccgactcccgcttcgcg
aaggtcacccgcctggcccaggagcacggcgcggccctgatcgccctcaccatcgacgag
cagggccaggcccgcaccgtcgaacacaaggtcgccatcgccgagcggctgatcgaggac
ctcaccggcaactggggcatccacgagtccgacatcctcatcgactgcctcaccttcacc
atctgcaccggccaggaggagtcccgcaaggacggcatcgccaccatcgaggccatccgc
gagctcaagcggcgccaccccgaggtgcagacgaccctgggcctgtcgaacatctccttc
ggcctcaacccggccgcccgcgtcctgctgaactccgtcttcctcgacgagtgcgtcaag
gccggccttgactcggcgatcgtccacgcctcgaagatcctgcccatcgcccgcttcgac
gacgagcaggtctccaccgccctcgacctcatctacgaccgccgcgagggcgactacgac
ccgctgcagaagctgatggccctcttcgagggcgtcaacaccaagtccctcaaggccggc
cgcgccgaggagctcctcgcgctgcccctggaggagcgcctgcggcagcgcatcgtcgac
ggcgagaagaacggcctggaggcggacctggacgaggccctgcagacccggcccgccctc
gacatcgtcaacgacaccctcctggagggcatgaaggtcgtcggcgagctcttcggatcc
ggccagatgcagctgccgttcgtcctccagtccgccgaggtcatgaagacggcggtggcc
tacctggagccgcacatggagaagtcggacgcggagggcaagggcaccatcgtcctggcc
accgtgcgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctctccaac
aacggctacaacgtcgtcaacatcggtatcaagcagccggtttcggcgatcgtggaggcc
gcgcaggagcaccgcgccgacgtcatcggcatgtccggcctgctcgtcaagtccaccgtg
atcatgaaggagaacctggaggagctgaaccagcgcaagctggccgccacctacccggtc
atcctcggcggcgccgccctcacccgcgcctacgtcgaacaggacctccacgagatctac
gagggcgaggtccgctacgcccgcgacgccttcgagggcctgcgcctgatggacgccctc
atcgccgtcaagcgcggcgtccccggcgccgccctgcccgagctcaagcagcgccgcgtc
cccaggcgcgacaccccgctgccggaggccgccgagccggaggagcccgggggccgctcg
gacgtctccgccgacaaccccgtcccgaccccgccgttctggggcacgcgggtcgtcaag
ggcatcccgctgaaggactacgcctcctggctcgacgagggcgccctcttcaagggccag
tggggcctgaagcaggcccgcgccggcggccccacctacgaggagctcgtcgagaccgag
ggccggccgcggctgcgcggcctgctggagaagctgcacaccgagaacctgctggaggcg
gccgtcgtccacggctacttcccgtgcgtctccaagggcgacgacctgatcatcctcgac
gaggccggcaacgagcggacccgcttcacctttccgcgccagcgccgcggccgccgcctg
tgcctcgcggacttcttccgccccgaggagtccggcgagaccgacgtcgtcggcctccag
gtcgtcaccgtcggctcgaggatcggcgaggccaccgccaagctgttcgcgtcggactcc
taccgcgagtacctggagctgcacggcctctccgtccagctcgccgaggccctcgccgag
tactggcacgcccgcgtccgcgccgagctcggcttcggcggcgaggaccccgccgacgtc
gaggacatgttcgccctgaagtaccggggcgcccgcttctccctcggctacggcgcctgc
cccgacctggaggaccgcgccaagatcgccgacctgctccggcccgagcggatcggcgtc
cacctgtcggaggagttccagctccacccggagcagtccaccgacgcgatcgtcatccac
caccccgaagcgaagtatttcaacgcacgctga

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