Streptomyces globosus: C0216_23950
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Entry
C0216_23950 CDS
T06864
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgz
Streptomyces globosus
Pathway
sgz00010
Glycolysis / Gluconeogenesis
sgz00020
Citrate cycle (TCA cycle)
sgz00620
Pyruvate metabolism
sgz00785
Lipoic acid metabolism
sgz01100
Metabolic pathways
sgz01110
Biosynthesis of secondary metabolites
sgz01120
Microbial metabolism in diverse environments
sgz01200
Carbon metabolism
sgz01210
2-Oxocarboxylic acid metabolism
Module
sgz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
C0216_23950 (aceE)
00020 Citrate cycle (TCA cycle)
C0216_23950 (aceE)
00620 Pyruvate metabolism
C0216_23950 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
C0216_23950 (aceE)
Enzymes [BR:
sgz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
C0216_23950 (aceE)
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Gene cluster
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AXE26107
UniProt:
A0A344U5D6
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Position
5396966..5399662
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AA seq
898 aa
AA seq
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MSDPVGKLPSELDQLPDRDTEETAEWAASLDAVAKAAGTRRAEYLLRRTLQHAESAGLAL
PKLLETDYVNTIPTSAEPDFPGDEEMEARITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFQHFFRGKEADGSGDQLYIQGHASPGIYARAFLDGRISEQQLDNFRQESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLENRKIKDTSNSHVWAFLGDGEM
DEPESTAALALAARERLDNLTFVVNCNLQRLDGPVRANFRIVQELEAQFRGAGWNVVKTL
WGSAWDELFRLDTTGALVRRLRETPDAQFQTYATRDAAYIREHFFGGDPALAALGALVSD
AKIAECFHTSRGGHEPRKVYAAYKAALEHKGAPTVILAQTVKGYTLGAGFESKNANHQMK
KLTIDEFKGMRDLLGLPIPDSAFDSGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
QVALPQPADKSFAPLLKGSGKQEMATTMAFVRLVKDLMRDKETGRRWVPIVPDEARTFGM
ESLFPSAGIYSPLGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGAMADFIAAATSYATH
GETMIPFYIFYSMFGWQRTGDQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLI
AATNPASLNYDPAFAYEIAVIVKDGLRRMYGEPTPGVDSDVFYYLTVYNEPKPQPAMPEG
VEEGIVKGLYRFNTAADLGDAAPAADAPRIQLMASGTAIHWILEAQRLLAAEWNVAADVW
SATSWGELRRDALEADEALLRGEERTPYVTRVLEGAPGPVLAVSDWMRQVPDQISQWVPQ
DYTSLGTDGFGLSDTRENARRHFGVDAESIVVAALAQLARRGEVPASSVKEARERYGL
NT seq
2697 nt
NT seq
+upstream
nt +downstream
nt
atgtccgaccccgtaggaaagcttccgagcgagctcgaccagctcccggaccgcgacacc
gaggagaccgccgaatgggcggcctcgctcgacgccgtcgccaaggccgccggtacgcgc
cgcgccgaatacctgctccgccgcaccctccagcacgccgagagcgccgggctcgccctg
ccgaagctgctggagacggactacgtcaataccatccccacctccgccgagccggacttc
cccggtgacgaggagatggaggcccgcatcacggcctggaaccgctggaacgcggccgcc
atggtgacccgcggctcgaagtacggcgtcggcggccacatcgccaccttcgcctccgcc
gcctggctgtacgagaccggcttccagcacttcttccgcgggaaggaggccgacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacgggcgcatctccgagcagcagctcgacaacttccgccaggagtccggcggcaacggc
ctgccctcctacccgcacccgcggcgcctgccgtggctgtgggagttcccgacggtctcc
atgggcctcggccccctctcggcgatctaccaggcgcgcttcaaccgctacctggagaac
cggaagatcaaggacacctccaactcccacgtctgggccttcctcggcgacggcgagatg
gacgagcccgagtcgacggccgcccttgccctcgcggcccgcgagcgcctcgacaacctg
accttcgtcgtcaactgcaacctgcagcgcctcgacggcccggtccgcgcgaacttccgc
atcgtccaggagctggaggcccagttccgcggcgccggctggaacgtcgtgaagaccctg
tggggctccgcctgggacgagctgttccgcctcgacaccacgggcgccctggtccgccgc
ctgcgcgagaccccggacgcgcagttccagacgtacgccacccgcgacgccgcctacatc
cgcgagcacttcttcggcggcgacccggccctcgcggcgctcggcgccctggtgtccgac
gcgaagatcgccgagtgcttccacacctcccgcggcggccacgagccccgcaaggtgtac
gccgcgtacaaggccgcgctggagcacaagggcgcgccgacggtcatcctggcgcagacc
gtcaagggctacaccctgggtgccgggttcgagtcgaagaacgcgaaccaccagatgaag
aagctgacgatcgacgagttcaagggcatgcgcgacctgctcggactcccgatcccggac
agcgccttcgacagcggcgtggtcccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcggcggcccggccccggcccgccgcgtccac
caggtggccctgccgcagcccgccgacaagtccttcgcgccgctgctcaagggctccggc
aagcaggagatggccacgacgatggccttcgtccgcctggtcaaggacctgatgcgggac
aaggagaccggccgccgctgggtgccgatcgtccccgacgaggcccgcaccttcggcatg
gagtccctgttcccgtccgcgggcatctactcgccgctggggcagacgtacgagccggtc
gaccgcgaccagctgatgtactacaaggaggccaaggacggccagatcctcaacgagggg
atcaccgaggccggcgccatggccgacttcatcgccgccgccacgtcgtacgcgacgcac
ggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacgggc
gaccagatgtggcagctcgccgaccagctcggcaagggcttcatcgtcggcgcgacggcc
ggccgcaccacactgaccggtgagggcctccagcacgccgacggccactcccacctgatc
gcggccacgaacccggcctcgctcaactacgacccggccttcgcgtacgagatcgcggtg
atcgtcaaggacggcctgcggcgcatgtacggggagcccacccccggtgtggactcggac
gtcttctactacctgacggtctacaacgagccgaagccgcagccggccatgcccgagggc
gtggaggagggcatcgtcaagggcctctaccgcttcaacacggcggcggacctcggcgac
gcggccccggccgccgacgccccgaggatccagctgatggcctcgggcaccgcgatccac
tggatcctggaggcgcagcggctgctggccgccgagtggaacgtcgccgccgacgtctgg
tccgccacctcctggggcgagctgcgccgggacgcgctggaggccgacgaggccctgctg
cgcggcgaggagcgcaccccgtacgtcacccgtgtgctggaaggcgcgccgggcccggtc
ctggccgtctccgactggatgcgccaggtccccgaccagatcagccagtgggtcccgcag
gactacacctcgctgggcacggacggcttcggcctctccgacacccgcgagaacgcccgc
cgccacttcggcgtcgacgccgagtcgatcgtcgtggccgcgctggcccagctcgcccgc
cgcggcgaggtgccggcgtcgtccgtgaaggaggcccgcgagcgctacggcctctga
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