Streptomyces globosus: C0216_24815
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Entry
C0216_24815 CDS
T06864
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgz
Streptomyces globosus
Pathway
sgz00010
Glycolysis / Gluconeogenesis
sgz00020
Citrate cycle (TCA cycle)
sgz00620
Pyruvate metabolism
sgz00785
Lipoic acid metabolism
sgz01100
Metabolic pathways
sgz01110
Biosynthesis of secondary metabolites
sgz01120
Microbial metabolism in diverse environments
sgz01200
Carbon metabolism
sgz01210
2-Oxocarboxylic acid metabolism
Module
sgz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
C0216_24815 (aceE)
00020 Citrate cycle (TCA cycle)
C0216_24815 (aceE)
00620 Pyruvate metabolism
C0216_24815 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
C0216_24815 (aceE)
Enzymes [BR:
sgz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
C0216_24815 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AXE26252
UniProt:
A0A344U5T1
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Position
5591949..5594681
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AA seq
910 aa
AA seq
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MASASDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERARER
RVAVPEMRSSDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGVYARAYLLDRLSEQQLDAFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMEARGIADTSRSHVW
AYLGDGEMDEPESLGQLSLAAREGLDNLTFVVNCNLQRLDGPVRGNGKVIQELESIFRGA
GWNVIKLIWDRSWDPLLAQDRDGILVNKMNSTPDGQFQTYATETGSYIREHFFGDDQRLR
AMVADMSDDQILHLGRGGHDHRKIYAAYAAARAHKGQPTVILAKTVKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHIPITDAQLESGAPPYYHPGRNSPEIQYMHDRRKALGGYVP
TRVVRARPLELPDDKAYAAVRKGSGQQSIATTMAFVRLLKDLMRDKEIGRRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAYGYEIAHIVRDGLRRMYGPEAEDVFYYLTVYNEPIQHPAEPD
GVDVEGILKGIHKVAAGTSGAIPAQIMASGVAVPWAVEAQRILAEEWNVRADVWSATSWN
ELRRDAVEAEEHNLLHPEEEQRVPYVTRKLSGAQGPFVAVSDWMRSVPDQIARWVPGAYT
SLGADGFGFADTRGAARRFFHIDAESVVLAVLTELAKEGRIDRSALKQAVDRYRLLDVAA
ADPGPAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcaatccgatcatcattggcggcctgccgagccaggtcccg
gacttcgatccggaggagacgcaggagtggctcgactccctcgacgccgccgtggacgaa
cgcggtcgcgaacgcgcccgctacctgatgctgcggctgatcgagcgggcccgcgagcgg
cgcgtggccgtgcccgagatgcgcagctccgactacgtcaacaccatcgccaccaaggac
gagccgttcttccccggcaacgaggagatcgagcgcaaggtcctgaacgccacccgctgg
aacgcggccgtcatggtctcgcgcgcccagcggcccggcatcggcgtgggcggccacatc
gccacgttcgcctcctcggcctccctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcacccggcgtc
tacgcccgcgcctacctgctggaccggctctccgagcagcagctcgacgcgttccgccag
gagaagtcgaaggccccgtacggcctgtccagctacccgcacccgcggctgatgccggac
ttctgggagttcccgacggtctcgatgggcctcgggccgatcggggcgatctaccaggcc
cggatgaaccggtacatggaggcgcgcgggatcgcggacacctccaggtcacacgtttgg
gcgtacctcggcgacggcgagatggacgagccggagtcgctgggccagctgtcgctggcg
gcgcgcgagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcggctcgac
ggtcccgtacgcggcaacggcaaggtcatccaggagctggagtcgatcttccgcggggcg
ggctggaacgtcatcaagctgatctgggaccgctcctgggacccgctgctggcgcaggac
cgggacggcatcctcgtcaacaagatgaactccacgccggacgggcagttccagacgtac
gccacggagaccggctcctacatccgcgagcacttcttcggcgacgaccagcggctgcgc
gcgatggtcgcggacatgtccgacgaccagatcttgcacctgggccgcggcggccacgac
caccggaagatctacgcggcgtacgcggcggcgcgcgcccacaagggccagccgacggtg
atcctggccaagacggtcaagggctggaccctcggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccgcctgcac
atcccgatcaccgacgcgcagctggagagcggcgccccgccgtactaccacccgggccgc
aactcgccggagatccagtacatgcacgaccgccgcaaggcgctgggcggctacgtcccg
acgcgggtggtgcgggcgcgtccgctcgaactgccggacgacaaggcgtacgcggcggtc
aggaagggctccggccagcagtcgatcgcgacgacgatggccttcgtccgcctgctgaag
gacctgatgcgggacaaggagatcggccggcgcttcgtgctgatcgccccggacgagtac
cgcaccttcggcatggactcgttcttcccgagcgccaagatctacaacccgctggggcag
cagtacgagtccgtcgaccgcgagctgctgctcgcgtacaaggagtccccgaccgggcag
atgctgcacgacggcatctcggaggcgggctgcacggcctcgctgatcgcggccggctcg
gcgtacgcgacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggc
ttccagcggacgggcgaccagttctggcagatggccgaccagctggcgcgcggcttcgtc
ctgggcgcgacggcgggccggaccaccctgacgggcgagggcctgcagcacgccgacggc
cactcccagctgctggcgtcgaccaacccggggtgcgtggcgtacgacccggcgtacggg
tacgagatcgcgcacatcgtccgggacggcctgcgccgcatgtacggtcccgaggccgag
gacgtcttctactacctgacggtctacaacgagccgatccagcatccggccgagcccgac
ggcgtggacgtcgagggcatcctcaagggcatccacaaggtggcggcgggcacgtccggc
gcgatcccggcgcagatcatggcctcgggcgtggcggtgccgtgggcggtcgaggcgcag
cggatcctggccgaggagtggaacgtcagggcggacgtctggtcggcgacctcctggaac
gagctgcgccgcgacgccgtcgaggcggaggagcacaacctgctgcacccggaggaggag
cagcgcgttccgtacgtgacgcggaagctttcgggcgcgcaggggccgttcgtcgcggtg
tcggactggatgcgctccgtgccggaccagatcgcccggtgggtgcccggtgcgtacacc
tcgctcggtgcggacggcttcggtttcgcggacacgcggggggcggcgcgccgcttcttc
cacatcgacgcggagtcggtggtgctggcggtgctgacggagctggcgaaggagggccgg
atcgaccggtccgcgctgaagcaggcggtggaccgctaccggctgctggacgtggcggcg
gccgacccgggcccggcgggcggcgacgcctag
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