Streptomyces halobius: K9S39_16015
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Entry
K9S39_16015 CDS
T09588
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
shau
Streptomyces halobius
Pathway
shau00020
Citrate cycle (TCA cycle)
shau00630
Glyoxylate and dicarboxylate metabolism
shau00785
Lipoic acid metabolism
shau01100
Metabolic pathways
shau01110
Biosynthesis of secondary metabolites
shau01120
Microbial metabolism in diverse environments
shau01200
Carbon metabolism
shau01210
2-Oxocarboxylic acid metabolism
Module
shau_M00009
Citrate cycle (TCA cycle, Krebs cycle)
shau_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
shau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K9S39_16015
00630 Glyoxylate and dicarboxylate metabolism
K9S39_16015
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K9S39_16015
Enzymes [BR:
shau01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
K9S39_16015
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
K9S39_16015
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
K9S39_16015
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
K9S39_16015
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UQA93150
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All DBs
Position
3498483..3502217
Genome browser
AA seq
1244 aa
AA seq
DB search
MSLQSPNSASISSDQEGQGKSPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAPSKPAESPAPAPSPAAPKPAAPAPAPAASAPAPAKPAPAPAKAAPAAKAKAAPAAE
APVGPEFVTLRGPSAAVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKV
SFTHLIGYAMVQALKAMPSMNCSFAEKDGKPTLVKPEHVNLGLAIDLVKPSGERQLVVAA
IKKAETLTFFEFWQAYEDIVRRARDNKLTMDDFTGVTASLTNPGGIGTVHSVPRLMPGQS
MIMGVGSMDYPAEFQGTSQDALNKMGISKVMTLTSTYDHRVIQGAASGEFLRIMSQLLLG
ENEFYDEIFKSLRIPYEPVRWLRDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLE
YHQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMKLRDILGVLRDSYCRTTGIEFMHI
QDPKQRKWIQDRVERSHKSPEREEQLRILRRLNSAEAFETFLQTKYVGQKRFSLEGGESV
IPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANVVGKSYAQIFREFEGNLDPKSMHGSG
DVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAVDPVVEGVARAKQDIIGKGGTDFTVLP
VQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESARSSMYATDVA
RMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPL
MYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVRDATTAPAVPEV
PQPKAEFPVYVDTAISQEVVKRIAESQVNVPERVTVHPRLLPQLQRRAAQVEDNAIDWGM
GETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAVLIDRVTGDDYTPLLYLAEDQARFNVY
DSLLSEYAAMGFEYGYSLARPEALVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVT
LLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAAPTLPSNYFHLLRWQVHNPHHKPLVV
FTPKSMLRLKAASSKTEEFTTGGFLPVIGDSAVDAQAVRKVVFCSGKVYYDLEAERAKRG
ANDTAIVRIERLYPLPGKELQAEIAKFPNAEKYLWAQEEPANQGAWPFLGLNLIDHLDLA
VGADIPHGERLRRISRPHGSSPAVGSAKRHQAEQAQLIAEVFDA
NT seq
3735 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacagtgcgagtatctcgtcggaccaagaggggcagggaaag
agtcctgctgccgcgtttggtcccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcgccgccgcgccgagcaagccggccgagagccccgctccggccccgtccccggccgcg
ccgaagcccgccgccccggctcccgcgcccgccgcgagcgctccggccccggcgaagccc
gccccggcgcccgccaaggccgcgcccgccgccaaggccaaggccgcaccggccgccgag
gccccggtcggccccgagttcgtcaccctgcgtggcccctcggccgccgtcgcgaagaac
atgaacgcctccctggagctgccgacggccacgtccgtccgcgccgtcccggtgaagctg
ctgttcgacaaccgcatcgtcatcaacaaccatctcaagcgcgcccgtggcgggaaggtc
tccttcacgcacctcatcgggtacgcgatggtgcaggccctcaaggccatgccgtcgatg
aactgctccttcgcggagaaggacggcaagccgacgctggtcaagcccgagcatgtcaac
ctcggtctggccatcgacctggtgaagcccagcggcgagcgccagctcgtcgtcgccgcc
atcaagaaggccgagacgctgaccttcttcgagttctggcaggcgtacgaggacatcgtc
cgccgcgcccgggacaacaagctgacgatggacgacttcaccggagtcaccgcgtcgctg
accaacccgggtggcatcggcaccgtccactccgtgccgcgtctgatgccgggccagtcc
atgatcatgggcgtcggctcgatggactaccccgccgagttccagggcacctcgcaggac
gccctgaacaagatgggcatctccaaggtcatgacgctgaccagcacctatgaccaccga
gtgatccagggcgccgcctccggcgagttcctgcggatcatgagccagctgctgctcggc
gagaacgagttctacgacgagatcttcaagtcgctgcggatcccctacgagccggtccgc
tggctgcgcgacatcgacgcctcgcacgacgacgacgtcaccaaggccgcccgggtcttc
gagctgatccactcctaccgggtgcgcggccatgtcatggccgacaccgacccgctggag
taccaccagcgcaagcaccccgacctggacatcaccgagcacggcctcaccctgtgggac
ctggagcgggagttcgcggtcggcggcttcgccggcaagtccatgatgaagctgcgcgac
atcctgggcgtgctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcacatc
caggaccccaagcagcgcaagtggatccaggaccgcgtggagcgttcccacaagtcgccc
gagcgtgaggagcagctgcgcatcctgcgccgactgaactccgccgaggcgttcgagacg
ttcctgcagaccaagtacgtcggccagaagcgcttctccctggagggcggcgagtccgtc
atcccgctgctggacgcggtcatcgactccgcggccgagtcgcgcctcgacgaggtcgtc
atcggcatggcccaccgcggccgcctcaacgtcctggcgaacgtcgtcggcaagtcgtac
gcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggc
gatgtgaagtaccacctgggcgccgagggcaccttcaccggcctggacggcgagcagatc
aaggtctcgctcaccgccaacccctcccacctggaggccgtggacccggtcgtcgagggt
gtcgcgcgcgccaagcaggacatcatcggcaagggcggcacggacttcaccgtgctgccg
gtccagctgcacggtgacgcggcgttcgccggccagggcgtggtggcggagacgctgaac
atgtcccagctgcgcggctaccgcaccggcggcacggtccacatcgtcatcaacaaccag
gtcggcttcaccgccgcgccggagtcggcccgctcctccatgtacgccacggacgtggcc
cgcatgatcgaggcaccgatcttccatgtgaacggtgacgacccggaggcggtcgtccgc
gtcgcccgtctggccttcgagttccgccaggcgttcaacaaggacgtcgtcatcgacctg
atctgctaccgccgtcgcggccacaacgagtcggacaacccggccttcacccagccgctg
atgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtcgctcatc
ggccgcggcgacatcacgctggaagaggccgagcaggcgctgcaggacttccagggccag
ctggagaaggtcttcaccgaggtccgcgacgccacgacggcgccggcggtgcccgaggtg
ccgcagcccaaggccgagttcccggtctacgtggacaccgcgatctcccaggaggtcgtc
aagcggatcgccgagtcccaggtcaacgtccccgagcgggtcaccgtccacccgcgtctg
ctgccgcagctgcagcgccgcgcggcccaggtggaggacaacgcgatcgactggggcatg
ggcgagaccctggccatcggttcgctgctgatggagggcaccccggtccggctcgccggc
caggactcccgccgcggcaccttcggccagcggcacgcggtgctcatcgaccgggtcacc
ggcgacgactacaccccgctgctctacctcgccgaggaccaggcccgcttcaacgtctac
gactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgctggcccgc
ccggaggcgctggtcatgtgggaggcgcagttcggtgacttcgtcaacggcgcgcagacc
gtcgtggacgagttcatctcctccgccgagcagaagtggggccagacctccggcgtcacc
ctgctgctgccgcacggctacgagggccagggcccggaccactcctcggcccgtatcgag
cgcttcctgcagctctgcgcccagaacaacatgacggtcgccgcgccgaccctgccgtcg
aactacttccacctgctgcgctggcaggtccacaacccgcaccacaagccgctggtcgtc
ttcaccccgaagtcgatgctgcgtctgaaggcggcgtcgtcgaagacggaggagttcacg
acgggcggtttcctccccgtcatcggcgacagcgcggtggacgcccaggccgtccgcaag
gtcgtcttctgctccggcaaggtctactacgacctggaggccgagcgggccaagcgcggc
gcgaacgacacggcgatcgtccgtatcgagcggctctacccgcttcccggcaaggagctc
caggcggagatcgccaagttcccgaacgccgagaagtacctgtgggcccaggaggagccg
gcgaaccagggtgcctggccgttcctcggtctcaacctgatcgaccacctggacctggcc
gtcggcgccgacatcccgcacggcgagcgcctgcgccgcatctcgcggccgcacggctcg
tcgccggccgtcggctccgccaagcggcatcaggcggagcaggcgcagctgatcgcggag
gtcttcgacgcgtag
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