Streptomyces halobius: K9S39_30265
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Entry
K9S39_30265 CDS
T09588
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
shau
Streptomyces halobius
Pathway
shau00010
Glycolysis / Gluconeogenesis
shau00020
Citrate cycle (TCA cycle)
shau00620
Pyruvate metabolism
shau00785
Lipoic acid metabolism
shau01100
Metabolic pathways
shau01110
Biosynthesis of secondary metabolites
shau01120
Microbial metabolism in diverse environments
shau01200
Carbon metabolism
shau01210
2-Oxocarboxylic acid metabolism
Module
shau_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
shau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
K9S39_30265 (aceE)
00020 Citrate cycle (TCA cycle)
K9S39_30265 (aceE)
00620 Pyruvate metabolism
K9S39_30265 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K9S39_30265 (aceE)
Enzymes [BR:
shau01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
K9S39_30265 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
UQA95574
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Position
complement(6659345..6662092)
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYINTIATKDEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGVYARAFLLDRLSEPQLDAFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSPSHVW
AYLGDGEMDEPESLGQLSLAAREGLDNLTFVVNCNLQRLDGPVRGNGKIMQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGILVNKLNSTPDGQFQTYATETGAYIRQHFFGDDHRLR
AMVENMTDDQILHLGRGGHDHKKIYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPIPDKDLEHGAPPYYHPGRDSEEIQYMHDRRKALGGYVP
TRVVRSKPLQLPGDKVYAGAKKGSGQQKIATTMAFVRVLKDLMRDKEIGKRFVPIAPDEY
RTFGMDAFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPIYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVAYDPAYGYEIAHIVKDGLRRMYGASAEFPHGEDIFYYLTVYNEPILH
PAEPADVDVEGILKGLHRVRPAEKGRHAAQILASGVAVPWAVEAQRILADEWNVKADVWS
ATSWNELRRDAVAAEEHNLLHPEEEQRVPYVTRKLQSAEGPKVAVSDWMRSVPDQIARWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAKEGKVDRSLLKQAIDRYQL
LDVTAAEAGEAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgaaacccgatcatcattggcggccttcccagccaggtcccg
gacttcgatcccgaagagacccaggaatggctcgactcgctcgacgctgccgtcgatgag
cgaggccgggaacgtgcccgctacctcatgcttcgcctgatcgagcgggcccgcgagaag
cgtgtggccgtgcccgagatgcgcagcacggactacatcaacaccatcgcgaccaaggac
gagccgttcttccccggcaacgaggagatcgagcgcaagatcctgaacgcgacccggtgg
aacgcggccgtcatggtgtcccgcgcccagcgccccggcatcggcgtcggcggccacatc
gccaccttcgcctcctccgcctccctctacgacgtgggcttcaaccacttcttccggggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcccccggcgtc
tacgcccgcgcgttccttctggaccggctgtccgagccccagctcgacgccttccgccag
gagaagtccaaggccccgaacggtctgtcgagctacccgcacccgcgcctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggccccctcggcgcgatctaccaggcc
cggatgaaccgctacatggaggcccgcggcatcgccgacacctccccgtcgcacgtgtgg
gcctacctcggcgacggtgagatggacgagccggagtcgctcggccagctgtccctcgcc
gcccgtgagggcctggacaacctgaccttcgtcgtcaactgcaacctgcagcgtctggac
ggcccggtccgcggcaacggcaagatcatgcaggagctggagtcgcagttccgcggcgcc
ggctggaacgtcatcaagctggtgtgggaccgcagctgggacccgctgctcgcgcaggac
cgcgacggcatcctggtcaacaagctcaacagcacgccggacggccagttccagacgtac
gccaccgagaccggtgcgtacatccgccagcacttcttcggtgacgaccaccggctgcgc
gccatggtcgagaacatgaccgacgaccagatcctgcacctggggcgcggcggtcacgac
cacaagaagatctacgcggcgtacgcggcggccaaggcgcacaagggccagccgacggtg
atcctcgcgcagaccgtcaagggctggaccctcggcccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgacgacctcaagcgcttccgtgaccggctgcac
ctgccgattccggacaaggacctggagcacggcgccccgccctactaccacccgggccgg
gactccgaagagatccagtacatgcacgaccgccgcaaggcgctcggcggttacgtcccg
acccgtgtcgtgcgcagcaagccgctgcagctgccgggcgacaaggtctacgcgggcgcc
aagaagggctcgggccagcagaagatcgccacgaccatggcgttcgtccgggtgctcaag
gacctgatgcgggacaaggagatcggcaagcgcttcgtgccgatcgcgcccgacgagtac
cgcaccttcggcatggacgcgttcttcccgtcggcgaagatctacaacccgctgggccag
cagtacgagtcggtggaccgtgaactgctgctcgcctacaaggagtcgccgaccggccag
atgctgcacgacggcatctccgaggcgggctgcaccgcgtcgctgatcgcggcgggctcc
gcctacgccacgcacggcgagccgctgatcccgatctacgtcttctactcgatgttcggg
ttccagcgcaccggtgaccagttctggcagatggcggaccagctcgcgcgcggctttgtg
ctcggcgcgaccgccggccgtacgacgctgaccggtgagggcctgcagcacgcggacggc
cactcgcagctgctggcgtcgaccaacccggcctgtgtcgcgtacgacccggcctacggc
tacgagatcgcgcacatcgtcaaggacggtctgcggaggatgtacggcgcgagcgccgaa
ttcccccatggcgaggacatcttctactacctgaccgtctacaacgagccgatcctgcac
ccggcggagcccgccgatgtggacgtcgagggcatcctcaagggtctgcaccgcgtgcgg
cccgccgagaagggccggcacgctgcccagatcctcgcgtcgggcgtggcggtgccgtgg
gccgtcgaggcgcagcggatcctcgcggacgagtggaacgtcaaggcggacgtctggtcg
gccacctcctggaacgagctgcgccgcgacgcggtggcggccgaggagcacaacctgctg
cacccggaggaggagcagcgcgtcccgtatgtgacgcggaagctccagagcgccgagggc
ccgaaggtcgcggtctcggactggatgcgttccgtgccggaccagatcgcgcgctgggtc
ccgggcacgtaccagtcgctgggcgccgacggcttcggcttcgcggacacccgtggtgcg
gcccgccgcttcttccacatcgacgcgcagtcgatcgtcctggccgtgctcaccgagctc
gccaaggagggcaaggtggaccgctcgctgctgaagcaggcgatcgaccggtaccagctg
ctggatgtcaccgccgccgaggcgggcgaggccggcggcgacgcgtag
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