Streptomyces hawaiiensis: CEB94_12800
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Entry
CEB94_12800 CDS
T06917
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
shaw
Streptomyces hawaiiensis
Pathway
shaw00010
Glycolysis / Gluconeogenesis
shaw00020
Citrate cycle (TCA cycle)
shaw00620
Pyruvate metabolism
shaw00785
Lipoic acid metabolism
shaw01100
Metabolic pathways
shaw01110
Biosynthesis of secondary metabolites
shaw01120
Microbial metabolism in diverse environments
shaw01200
Carbon metabolism
shaw01210
2-Oxocarboxylic acid metabolism
Module
shaw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
shaw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CEB94_12800 (aceE)
00020 Citrate cycle (TCA cycle)
CEB94_12800 (aceE)
00620 Pyruvate metabolism
CEB94_12800 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CEB94_12800 (aceE)
Enzymes [BR:
shaw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CEB94_12800 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
RL
Motif
Other DBs
NCBI-ProteinID:
QCD55653
UniProt:
A0A6G5RBX0
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Position
2732488..2735235
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AA seq
915 aa
AA seq
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MASASDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAFLLDRLGEEHLDGFRQ
EKSKAPHGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMHARGIADTSKSQVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGA
GWNVIKLVWDRSWDPLLAQDRDGVLVNKMNTTPDGQFQTYATETGAYIRDHFFGDDHRLR
AMVEGMTDDQILHLGRGGHDHKKIFAAYKAAAEHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPIPDKELESGVPPYYHPGRDSEEIQYMHDRRKSLGGYVP
TRVVRSKPLALPEDKTYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKESPNGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMSDQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIVKDGLRRMYGGSEEHPHGEDVFYYLTVYNEPIQH
PAEPESVDVDGILKGLYRFSEGTAGSIPAQILASGVAVPWAVEAQKILAEDWNVKADVWS
ATSWNELRREAVDCERHNLLHPEEEQRVPYVTRKLADAQGPVVAVSDWMRSVPDQIARWV
PQTYQSLGADGFGFADTRGAARRFFHIDAQSIVVGVLTELAREGKVDRSVLKQAIDRYQL
LDVSAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcaacccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaagagactcaggagtggctcgactccctcgacgccgccgtcgacgag
cgcggccgggaacgggcccgctacctgatgctgcggctgatcgagcgggcccgcgagaag
cgcgtggccgtgccggagatgcgcagcacggattacgtcaacaccatccccaccaagagc
gagccgttcttcccgggcaacgaggagatcgagcgcaaggtcctgaacgccacccgctgg
aacgcggcggtgatggtctcccgggcccagcgccccggcatcggcgtcggcggccacatc
gccacgttcgcctcctccgcctccctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccaggtcttcttccagggccacgcctccccgggcatc
tacgcccgcgccttcctgctggaccggctcggcgaggagcacctggacggcttccgccag
gagaagtcgaaggcgccgcacgggctgtcgtcgtacccgcacccgcggctgatgccggac
ttctgggagttcccgacggtgtcgatgggcctcggcccgatcggcgcgatctaccaggcg
cggatgaaccgctacatgcacgcgcgcgggatcgccgacacctcgaagtcacaggtctgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctgggccagctgtccatcgcc
gcccgggagggcctggacaacctgaccttcgtcgtgaactgcaatctccagcggctcgac
ggtccggtacgcggcaacgggaagatcatccaggagctggagtcgatcttccgtggcgcc
ggctggaacgtgatcaagctggtctgggaccgcagctgggacccgctgctcgcccaggac
cgcgacggcgtgctggtcaacaagatgaacaccacgccggacgggcagttccagacgtac
gccacggagaccggcgcgtacatccgcgaccacttcttcggtgacgaccaccggctgcgg
gcgatggtcgagggcatgaccgacgaccagatcctgcacctgggacgcggtggccacgac
cacaagaagatcttcgcggcgtacaaggcggccgccgagcacaagggccagccgacggtc
atcctcgccaagacgatcaagggctggacgctcggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccgcctccac
ctgccgatcccggacaaggagctggagtccggcgtgccgccgtactaccacccgggccgg
gactcggaggagatccagtacatgcacgaccgccgcaagtcgctcggcggttacgtcccc
acgcgcgtggtccgctccaagccgctggcgctgcccgaggacaagacgtacgcgaccgtg
aagaagggctcgggtcagcagtccatcgcgacgacgatggccttcgtccggctcttgaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcgccggacgagtac
cgcacgttcggcatggactcgttcttcccgagtgcgaagatctacaacccgctcggccag
cagtacgagtcggtcgaccgcgatctgctgctcgcgtacaaggagtcgccgaacggtcag
atgctgcacgacggcatctcggaggcgggctgcacggcgtcgctgatcgccgccggatcg
gcgtacgcgacccatggcgagccgctcatccccgtctacgtcttctactcgatgttcggc
ttccagcgcaccggcgaccagttctggcagatgtccgaccagctggcgcgcggtttcgtc
ctgggcgcgaccgccggccgtacgaccctgaccggtgagggcctccagcacgccgacggc
cactcgcagctgctggcctccacgaacccgggctgcgtggcgtacgacccggcgttcggc
ttcgagatcgcgcacatcgtgaaggacggcctgcgccggatgtacggcggctccgaggag
cacccgcacggcgaggacgtcttctactacctgaccgtctacaacgagccgatccagcac
ccggccgagccggagagcgtggacgtcgacggcatcctcaagggcctctaccggttcagc
gagggcacggcgggctcgatcccggcgcagatcctggcgtccggtgtcgcggtgccgtgg
gccgtcgaggcgcagaagatcctcgccgaggactggaacgtcaaggcggacgtctggtcg
gcgacctcctggaacgaactgcggcgcgaggccgtggactgcgagcggcacaacctgctg
caccccgaggaggagcagcgggtgccgtacgtgacgcgcaagctcgcggacgcgcaggga
ccggtcgtggccgtgtccgactggatgcggtccgttccggaccagatcgcgcgctgggtg
ccgcagacgtaccagtcgctcggcgcggacggcttcggcttcgcggacacgcggggcgcg
gcccgccggttcttccacatcgacgcgcagtcgatcgtggtcggcgtgctgaccgagctg
gcccgtgagggcaaggtcgaccgctcggtgctcaagcaggccatcgaccggtaccagctg
ctcgacgtgtcggccgccgacccgggggccgcgggcggcgacgcgtag
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