Streptomyces hawaiiensis: CEB94_27715
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Entry
CEB94_27715 CDS
T06917
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
shaw
Streptomyces hawaiiensis
Pathway
shaw00020
Citrate cycle (TCA cycle)
shaw00630
Glyoxylate and dicarboxylate metabolism
shaw00785
Lipoic acid metabolism
shaw01100
Metabolic pathways
shaw01110
Biosynthesis of secondary metabolites
shaw01120
Microbial metabolism in diverse environments
shaw01200
Carbon metabolism
shaw01210
2-Oxocarboxylic acid metabolism
Module
shaw_M00009
Citrate cycle (TCA cycle, Krebs cycle)
shaw_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
shaw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CEB94_27715
00630 Glyoxylate and dicarboxylate metabolism
CEB94_27715
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CEB94_27715
Enzymes [BR:
shaw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CEB94_27715
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CEB94_27715
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CEB94_27715
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CEB94_27715
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QCD58207
UniProt:
A0A6G5RKV3
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All DBs
Position
complement(5881678..5885511)
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AA seq
1277 aa
AA seq
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MSPQSPSNSSISTDTDQAGKNPAASFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAASAPAGTAAAGAAGTTTAQAAAPAAPAQAPAPAAEKPAAAPAPASAPAQAKPAAQA
PAQAPAPAKAAPVAKPAAAKPATPAKKAEPAGEAPAGPEQIVLRGPAAAVAKNMNASLEV
PTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEK
DGKPTLVKPEHINFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGK
LGMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGI
SKVMTLTSTYDHRVIQGAASGEFLRIVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDA
SHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAV
GGFAGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHTKPEREEQLR
ILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVVGMAHRG
RLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVAN
PSHLEAVDPVLEGVSRAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGY
RTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFE
FRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITL
EEAEQALQDYQGQLEKVFTEVREATSQPNIVETSDPQAEFPVAVNTAVTTEVVKRIAESQ
VNIPDHITVHPRLLPQLQRRASMVEDGTIDWGMGETLAIGSLLLEGVPVRLAGQDSQRGT
FGQRHAVIIDRSTGEEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPEALVMW
EAQFGDFVNGAQTVVDEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQMCA
QNNMTVAMPTSPSNYFHLLRWQSHNPHHKPLVVFTPKSMLRLKAAAAKAEEFTTGQFQPV
IGDASVDPAAVRKVVFCAGKVYYDLEAERQKRGVTDTAIIRIERLYPLPGTELQAEIKKY
PNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSA
KRHQAEQEQLVREVFEA
NT seq
3834 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcggggaag
aaccctgccgcgtcgttcggtgccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcgccgctgccgcctcggctccggcgggtaccgcggccgcgggggccgcggggaccacc
accgctcaggcggccgctccggccgctccggcccaggcccccgccccggcggccgagaag
cccgccgccgctccggcccccgcctcggctccggcccaggcgaagcccgccgcgcaggct
ccggctcaggcccccgctccggcgaaggccgcccccgtcgcgaagccggccgccgccaag
ccggccactcccgcgaagaaggccgagcccgccggcgaggcccccgcgggccccgagcag
atcgtgctgcgcggccccgccgccgcggtcgcgaagaacatgaacgcctccctggaggtg
cccacggccacgtccgtgcgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtc
atcaacaaccacctgaagcgggcccggggcgggaagatctccttcacgcacctgatcggc
tacgcgatggtgcaggccatcaaggccatgccgtcgatgaactactccttcgcggagaag
gacggcaagcccaccctggtcaagccggagcacatcaacttcggcctcgccatcgacctg
gtcaagcccaacggcgaccgtcagctcgtggtggcgggcatcaagaaggccgagacgctg
aacttcttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaag
ctgggcatggacgacttcaccggcgtgacggtctccctgaccaaccccggcggcctcggc
acggtccactccgtgccgcgtctgatgcccggccagtcggtcatcatgggcgtcggctcc
atggactacccggccgagttccagggcacgtcccaggacacgctgaacaagctcggcatc
tcgaaggtcatgacgctcacgtcgacctacgaccaccgggtgatccagggcgcggcctcc
ggcgagttcctgcggatcgtcgcgaacctcctcctcggtgagaacggcttctacgacgac
atcttcgaggcgctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcg
tcccacgacgacgacgtcaccaaggccgcccgcgtcttcgagctgatccactcctaccgg
gtccgcggccacgtcatggccgacaccgacccgctggagtaccagcagcgcaagcacccc
gacctggacatcaccgagcacggcctcacgctctgggacctggagcgcgagttcgccgtc
ggcggcttcgccggcaagtcgatgatgaagctgcgcgacatcctcggcgtcctgcgcgac
tcgtactgccgcaccaccggcatcgagttcatgcacatccaggacccgaagcagcgcaag
tggatccaggaccgcgtcgagcgcccgcacaccaagccggagcgcgaggagcagctgcgc
atcctgcgccggctgaacgccgcggaggccttcgagaccttcctgcagacgaagtacgtc
ggccagaagcgcttctccctggagggcggcgagtccgtcatcccgctgctggacgccgtg
ctggactcggccgccgagtcccgcctggacgaggtcgtcgtgggcatggcccaccgcggc
cgcctgaacgtcctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttc
gagggcaacctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggc
gccgagggcaccttcaccggcctcgacggcgagcagatcaaggtctccctggtcgcgaac
ccgtcgcacctcgaagccgtcgacccggtcctggagggcgtctcgcgcgccaagcaggac
atcatcaacaagggcggcacggacttcacggtcctgccggtggcgatccacggcgacgcg
gccttcgcgggccagggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctac
cgcaccggcggtacggtccacatcgtcatcaacaaccaggtcggcttcacggcggccccc
gagtcctcgcgttcctccatgtacgcgacggacgtggcccgcatgatcgaggccccgatc
ttccacgtgaacggcgacgacccggaggccgtggtccgcgtggcccgtctggccttcgag
ttccgccaggcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgtcgcggt
cacaacgagtcggacaacccggccttcacccagccgctgatgtacgacctgatcgacaag
aagcgctcggtgcgcaagctctacaccgaatccctcatcggtcgcggcgacatcaccctg
gaagaggcagagcaggcgctgcaggactaccagggccagctggagaaggtcttcacagag
gttcgcgaggccacctcgcagccgaacatcgtggagacgtccgacccgcaggccgagttc
ccggtcgccgtgaacaccgcggtgaccacggaggtcgtcaagcgcatcgccgagtcgcag
gtcaacatccccgaccacatcaccgtccacccgcgtctgctgccgcagctgcagcgccgg
gcgtcgatggtcgaggacggcaccatcgactggggcatgggcgagaccctcgcgatcggc
tccctcctgctggagggcgtcccggtccgcctggcgggccaggactcgcagcgcggtacg
ttcggccagcgccacgcggtcatcatcgaccgcagcaccggcgaggagtacacgccgctg
cagtatctctccgaggaccaggcgcggctgaacgtctacaactccctcctctccgagtac
gcggcgatgggcttcgagtacggctactcgctggcccgccccgaggcgctcgtgatgtgg
gaggcgcagttcggcgacttcgtcaacggcgcccagacggtcgtggacgagttcatctcg
tcggccgagcagaagtgggcccagacgtccggcgtcgtcctgctcctgccgcacggctac
gagggccagggccccgaccactcctcggcccgcccggagcgcttcctccagatgtgcgcc
cagaacaacatgacggtcgccatgccgacgtcgccgtcgaactacttccacctcctgcgg
tggcagtcgcacaacccgcaccacaagccgctggtggtcttcacgccgaagtcgatgctg
cgcctgaaggcggcggcggcgaaggcggaggagttcacgacgggccagttccagccggtc
atcggcgacgcgtcggtggacccggccgcggtcaggaaggtcgtcttctgcgcgggcaag
gtctactacgacctcgaggccgagcgccagaagcgtggcgtgacggacacggcgatcatc
cgcatcgagcgcctgtacccgctgccgggtaccgagctccaggcggagatcaagaagtac
ccgaacgccgagaagtacctgtgggcccaggaggagccggcgaaccagggtgcctggccg
ttcatcgcgctcaacctgatcgaccacctggacctcgcggtcggcgcggacgtcccgcac
ggcgagcggctgcggcgcatctcgcgcccgcacggctcgtccccggcggtgggttccgcg
aagcggcaccaggcggagcaggagcagctggtgcgtgaggtgttcgaggcgtaa
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