KEGG   Shewanella sp. LZH-2: JM642_16060
Entry
JM642_16060       CDS       T10525                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
shel  Shewanella sp. LZH-2
Pathway
shel00270  Cysteine and methionine metabolism
shel00450  Selenocompound metabolism
shel00670  One carbon pool by folate
shel01100  Metabolic pathways
shel01110  Biosynthesis of secondary metabolites
shel01230  Biosynthesis of amino acids
shel04981  Folate transport and metabolism
Module
shel_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:shel00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    JM642_16060 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    JM642_16060 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    JM642_16060 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    JM642_16060 (metH)
   04980 Cobalamin transport and metabolism
    JM642_16060 (metH)
Enzymes [BR:shel01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     JM642_16060 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: QRK78780
LinkDB
Position
3635699..3639433
AA seq 1244 aa
MAISLHRASQTLADIRNQLSKRILILDGAMGTMIQGYKLEEADYRGERFKDWHTDVKGNN
DLLVLTQPHIIKQIHTDYLLAGADIIETNTFNATTIAMADYDMQSLSAEINREGARLARE
ACDEIEKATGKPRYVAGVLGPTNRTCSISPDVNDPGYRNIHFDELVTAYCESTRALIEGG
ADIIMVETIFDTLNAKAALFAIETVFDELFGANSPARLPVMISGTITDASGRTLTGQTTE
AFYNSLRHIKPLSIGLNCALGPKELRPYVEELSRIAECYVSAHPNAGLPNEFGGYDETPK
DMASVIQEWAREGMLNIIGGCCGSTPEHIKVIREAVEPFAPRVLPEIPVACRLAGLEPLT
IDAQTLFVNVGERTNVTGSAKFLKLIKEGKFEQALDVAREQVESGAQIIDINMDEGMLDG
VEVMHKFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEEKFIEQ
ATLVKRYGAAAIIMAFDEQGQADTKARKVEICTRAYRVLVDKVGFPPEDIIFDPNIFAIA
TGIDEHDNYAVDFIDAIKEIKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIK
VGMDMGIVNAGQLAIFDDIDPELKVRVENVVLNLPCPVEGSSNTEQLLDIAEKFRGDGSS
AAKKEDLEWRSWPVNQRLAHALVKGITEFIDEDTEAARQAASRPLDVIEGPLMDGMNIVG
DLFGSGKMFLPQVVKSARVMKKAVAYLNPFIEKEKVAGQSNGKILMVTVKGDVHDIGKNI
VGVVLACNGFEVFDLGVMVSVERILEAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREG
LTIPAIIGGATCSKIHTAVKIAPHYPHGAIYIADASRAVPMVSKLVSNETRQATIDETYA
EYDDMRTKRLSQAKRKEIVSLEAARQNRCQHDWANYTPFKPNVLGRQVFEDYPLTDLVDR
IDWTPFFRAWELHGHYPEILTDKVVGVEAQKLFADGQAMLTKIIEEKWLTAKGVIGLFPA
NTVNFDDIELYTDETRTEVELTTHHLRMQLERVGNDNFCLADFVAPKDSGVADYMGGFAV
TAGHGIDEHIARFEANHDDYNAIMLKCLADRLAEAFAERMHERVRKEFWGYAADEQLDNE
ALIREKYKGIRPAPGYPACPDHTEKGLLWELLKPNETIDLNITESYAMFPTAAVSGWYFA
HPKSRYFGVSNIGRDQVEDYAKRKGMTVAETEKWLAPVLDYDPE
NT seq 3735 nt   +upstreamnt  +downstreamnt
atggcgatatctctccatcgagccagccaaacactggcagacattcgcaaccagttgtca
aagcgcattctaattttagacggcgccatgggcactatgatccaaggctacaagctagaa
gaagccgattaccgtggcgagcgtttcaaggattggcataccgacgttaagggcaataac
gatctcttagtgctcacacagccacacatcatcaaacaaattcacaccgactacctatta
gctggtgccgatattattgaaaccaacactttcaacgccaccactatcgccatggccgac
tacgatatgcagtcgctgtccgccgaaattaaccgtgaaggtgcgcgcctcgcccgtgag
gcctgtgatgaaatcgaaaaagccacgggtaaaccacgttatgtcgccggtgtgttagga
cccactaaccgtacctgctctatcagccccgatgttaacgatcccggatatcgtaatatc
cactttgatgagttagtgaccgcttactgcgaatcgacccgcgccctgattgaaggcggc
gccgatatcattatggtcgagaccatcttcgataccttaaacgctaaggccgcattattt
gccatcgaaaccgtgttcgatgaactctttggcgctaactcgccagcacgtttgccagtg
atgatctccggcactattaccgatgcctcgggccgaacccttaccggacaaaccaccgaa
gccttttataactcccttcgccatatcaagccgttatctatcggccttaactgcgccctt
gggccaaaagagctgcgtccctacgttgaagaactgtcacgcatcgccgaatgttatgtg
tcggcgcaccctaacgcgggtctaccaaacgagtttggcggttacgatgaaaccccaaaa
gacatggccagcgttatccaagaatgggcccgtgaaggcatgctcaacattattggcggc
tgctgtggtagcacacccgagcatattaaggtcattcgcgaagcggtggaaccgtttgcc
ccgcgcgtattacccgagatccccgtcgcctgccgtttagcaggtttggaaccgctcact
atcgacgcccaaaccctgtttgtgaacgtgggtgagcgcaccaacgttactggctcggcc
aaatttttaaagctgatcaaagaaggcaagttcgaacaggcgctcgatgtcgcccgtgaa
caggtagaaagcggcgcgcagatcatcgacatcaacatggacgaaggcatgctcgatggc
gtggaggtgatgcataagttcttaaatcttatcgcctctgagccagatatcagccgcgtg
ccgattatgatcgactcctcgaagtgggaagtgattgaagcgggcctcaaatgtattcaa
ggcaagggtattgttaactctatctccctcaaagaaggcgaagagaagtttatcgagcag
gcaaccctcgttaaacgctacggcgcggcggccattattatggcgttcgacgagcaaggc
caagccgatacgaaggcgcgcaaagtcgaaatctgtacccgcgcctaccgcgtgctggtc
gataaggtcggctttccgcccgaagacattatcttcgacccgaacatcttcgccattgcc
acgggtatcgatgagcacgataactatgctgtcgattttattgatgccattaaagaaatt
aaggccaccctgccccacgcgatgatttcgggcggggtatcgaacgtgtcgttctccttc
cgcggtaacaacccagtgcgtgaggcgattcacgcagtattcctgtaccacgcgattaaa
gtcggtatggatatggggattgtcaacgcgggccagttagcgatttttgacgatatcgac
ccagagcttaaagtacgggtcgagaacgtggtgctcaacctgccttgcccggttgaaggc
tcgagcaataccgagcaattgcttgatattgctgaaaaattccgtggcgatggctcaagt
gccgctaaaaaagaagatttagaatggcgctcatggccagttaatcaacgtctcgcccat
gcgctggtgaaaggcatcaccgaatttatcgacgaagatactgaagcggctcgccaagct
gcctcccgtccgctggatgtgattgaaggcccgctaatggacggtatgaatatcgtcggc
gacctgtttggctcgggtaaaatgttcctgccacaggtggtcaaatccgcgcgggtgatg
aaaaaggccgtggcctacctcaatccctttattgaaaaagaaaaagtcgcaggtcagtcg
aacggtaagattttgatggtgaccgtaaaaggcgatgtgcacgatatcggcaagaatatt
gtcggcgtggtgcttgcctgcaatggctttgaagtgttcgatttaggcgtgatggtgtca
gtagagcgcattcttgaggcggtgaaagaacacaatatcgatattatcggcatgtcaggg
cttatcaccccaagcctcgatgagatggtgcacaatgtgaaaaccttccaccgtgaaggg
ctcaccattccagcgattatcggcggcgctacctgctcgaaaatccatactgcggtgaag
attgcgccgcattatccccatggcgcgatttacattgccgatgcctcgcgcgcagtgcct
atggtcagcaagctagtcagcaatgaaactcgccaagcgaccattgatgaaacctacgcc
gagtatgacgatatgcgcaccaagcgtttatcccaagctaagcgtaaggaaatcgtctcg
ctagaggccgcccgtcaaaaccgctgccagcacgattgggccaactacaccccattcaaa
cctaacgtgctcggtcgccaagtatttgaagactatccattaaccgatttagtcgaccgc
atcgactggacgcccttcttccgcgcatgggagctgcacggtcattaccctgaaatctta
accgacaaagtagtcggcgttgaggcgcaaaagctgttcgccgatggtcaggcgatgctt
acaaaaatcatcgaagaaaaatggctcaccgccaagggcgtgattgggctattccccgcc
aataccgtcaacttcgatgatattgagctgtacacagatgagactcgcacagaggttgag
ctgaccacccatcacctgcggatgcaacttgagcgggtcggtaacgataacttctgtctg
gccgattttgtcgcgcccaaagactcaggcgttgccgactatatgggcggctttgcggtt
accgcaggccatgggattgatgagcatatcgcccgctttgaggcgaaccatgatgactac
aacgccattatgctcaagtgtttagccgaccgtttagccgaagcctttgccgagcggatg
cacgagcgcgtacgtaaagagttttggggttatgccgccgatgagcagctcgataacgag
gcgttaattcgcgaaaaatacaagggcattcgccctgcaccgggttaccccgcttgcccg
gatcacaccgaaaaaggcctgttgtgggaactgttaaagccgaatgaaaccatcgactta
aacattaccgaaagctacgccatgttccctaccgccgcagtatcgggctggtactttgcc
cacccgaaatcccgctactttggcgtgagtaatattggtcgcgatcaggtggaggattac
gcgaagcgtaaagggatgactgttgcagagacggagaagtggctagcgccagtgcttgac
tatgatcccgagtaa

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