Sarcophilus harrisii (Tasmanian devil): 100914310
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Entry
100914310 CDS
T02286
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01524
Platinum drug resistance
shr03440
Homologous recombination
shr03460
Fanconi anemia pathway
shr04120
Ubiquitin mediated proteolysis
shr04151
PI3K-Akt signaling pathway
shr05206
MicroRNAs in cancer
shr05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100914310 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
100914310 (BRCA1)
03460 Fanconi anemia pathway
100914310 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
100914310 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100914310 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
100914310 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100914310 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
shr01009
]
100914310 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
shr04121
]
100914310 (BRCA1)
03036 Chromosome and associated proteins [BR:
shr03036
]
100914310 (BRCA1)
03400 DNA repair and recombination proteins [BR:
shr03400
]
100914310 (BRCA1)
Enzymes [BR:
shr01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100914310 (BRCA1)
Protein phosphatases and associated proteins [BR:
shr01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100914310 (BRCA1)
Ubiquitin system [BR:
shr04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
100914310 (BRCA1)
Multi subunit type E3
BRCC complex
100914310 (BRCA1)
Chromosome and associated proteins [BR:
shr03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
100914310 (BRCA1)
DNA repair and recombination proteins [BR:
shr03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
100914310 (BRCA1)
BRCA1-A complex
100914310 (BRCA1)
BRCA1-B complex
100914310 (BRCA1)
BRCA1-C complex
100914310 (BRCA1)
BRCA complex
100914310 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
100914310 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-RING_2
zf-C3HC4_4
zf-RING_5
zf-C3HC4_3
RING_XB3-XBAT31
zf-RING_6
BRCT_2
zf-Nse
zf-RING_10
zf-ANAPC11
Prok-RING_4
zf-rbx1
Motif
Other DBs
NCBI-GeneID:
100914310
NCBI-ProteinID:
XP_031822205
LinkDB
All DBs
Position
4:complement(338632421..338708477)
Genome browser
AA seq
1828 aa
AA seq
DB search
MDLSTVRINEVKNVLIGMQKILECPICLELIKEPVSTTCDHIFCKFCMLKLLGKKKGPSQ
CPLCKNNVTKRSLRESTRFKQLVEGLLKTIRAFELDTGFLFSNSQDSSKWEKRTPEPLKK
EATIIQSMGYRNRTKRFRASEPENPTLEASLGVQLFDLGIRKGSLRRKQKKCIKNNAVYI
ELGSDSSEDGAKNAICNSVKDQELCQTSPQGTRSKARVKPRGKAEFELSERTIKSLQQHH
SNTKDAHVIEENATGGHPKEPQSISSSNLNMKPCGTDTHASSLLPETSTLLPNTDRMTVE
KAELCNKSKQSGLARNQQSGLDESKGICSTGKTPSVEEQPELNAHHLCEKQELKEKPQGP
EGTRGNPQNCLSGTKLKSSIQKVNEWLSRSNDILASDCSLDKNHKQNAEIASALEDGHPD
NSDGNSSISEKTDVVADTADETWLHMPERSYPKPAENNNIKDKIFGKTYRRKSGHPNLNH
ITENLVVETVVPDSLVPPEPLKNTKLKRKRKTICDLQPEDFIKKTVPITHKTPEKKHAAD
QTFEREQNDQVMNMDNGHPEQKALNGHAGEMKEAQTSELFSAEKESTLRTETEPAAGLNG
GETNITKKDKPRKQPSFKVVCALELGHDGSPSSSNETELQIDSYPSSEEIRKKKNSEQNQ
LRRSRRLQQVSEEIAVGAKKAHKPDDQAEESCVTEVVSELKLGNVCACAPDNLSTDKDQV
LASCSFTGDERSLEVIPSSQDQDLSLSGREELRGERSQGSLGTVEVPDTAWDTQDSTSLF
PADTPQNSKAGPSPHRSHCEIMEIKEFLESSSSKNTESSAEDLRSPMKQEVKNASKTITE
MEDSELDTQYLQNTFKRSKRQSFALCSSPRQEYMKTCAVPGAVSQQSTVHRYQEKEKQEN
RESNKPVQPKPAVMKEKGKPGDHAKCSTREVSRLCRIASLNSDNDCEPIAEISQGISQVP
DQKQSVSPARSFDSKIIYAKNFLEERLDGQTTCPETAMGNESLAQSSISLISQSNSREYI
SKPTDLIIGIGSSGEGTQAEKSENKESELNTPPKLKLMQPQISQQIFPQDNCKGYKRKGK
GGNGKSAQAISTDLSPYLEQTKESIHSSQVWSETPDLLDSEGEIKENTSFAESDINEQSA
IFGKIGKRFQVKQSRKSLSPFVHRNPTLTRRARKLESSEEEEDASSEEGDLPSFQDLIFG
KAASTPSQPTKNKTMGLELSANKAKENPDFSLNRNRMNASSPQLSSREASQDDNSSQESE
CSGSLFSSHSNSLEDLTGKANDKDSALVFDSSKQGRNQPRTQEIQSADDVPRISEDEGER
EIDLDEDHHLKDQGVDSNLGKYASGYDSETSHPGDISQLSSQSDILTTQQRDTMQDNLKK
LQQEMAVLEAVLEQHGSQTSNSPLSQESRLCPSMDQPDLKQTSTEKGAEKTVEYHESQNS
QNLSSDKSQAFPGDSSSSKNEEPGVEGSSLLENQILKGVWSPLGHSRNLQKVDSSFRQGI
DRITALKEKQQSPPEEHNVMMEQICVLKPNLEASPELESGIKVYPEKTKSSPQEHKDTAL
RDILNLPTSTSALRLQTGQRTNPSAPNAPAWNGKGPLEEASASKSVKKGGAGSPKMSLVA
SGLTPKEHMLVQKFARKTQSTLSNQITEGTTHVIMKTDAEFVCERTLKYFLGIAGGKWVV
SFLWVVQSFKEGKVLPECDFEVRGDVINGRNHRGPERARESRGVKIFKGLEICCYGPFTD
MSTDQLEWMVRLCGASVVRKPSLLRPRLGSSPVVVVQPDAWEDDSSFEGIGLICEAPVVT
REWVLDSIACYQRQELDTYLIAQTSGCC
NT seq
5487 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctacagtcaggatcaacgaagtaaagaatgtcctcattgggatgcagaaa
atcttagaatgtcctatctgtctggaattgattaaagagcctgtttctacaacctgtgac
cacatattttgcaaattttgtatgttgaagcttcttggcaagaagaagggaccatctcag
tgtccactatgcaagaacaatgtaaccaaaagaagcctacgagaaagtacaaggtttaaa
cagcttgtagaaggactgctgaaaactattcgtgcttttgagcttgacacgggattcctt
ttttcaaacagccaggattcttcaaagtgggagaagaggactcctgagcctctaaagaaa
gaagctactatcattcaaagtatgggctacagaaaccgcacaaaaagattcagagccagt
gaaccagaaaaccccaccttggaggccagtcttggtgtccagctttttgaccttggcatc
agaaaaggttcgctgagaagaaaacaaaagaaatgcattaaaaataatgctgtctacatt
gaattaggatctgattcttctgaagatggtgcaaaaaatgctatctgtaacagtgtgaaa
gatcaagaattgtgccaaacatcaccacaaggaaccagatctaaagccagagtaaagccc
aggggaaaagctgagtttgagttatctgagaggaccataaagagcctgcaacagcatcat
tctaataccaaagatgctcacgtcattgaggagaatgccactgggggacatccaaaggag
cctcagagtatttcttcttcaaacttgaatatgaagccatgtggcacagacactcatgcc
agctcattactgcctgaaacctccactttattgcccaacacagacagaatgactgtagaa
aaagctgagctctgtaataaaagcaaacagtctggcttagcaaggaaccaacagagtgga
ctggatgaaagtaagggaatatgtagtactgggaagacccccagtgtagaagagcagcct
gagctgaatgcccatcatctgtgtgagaagcaagaactaaaggagaagccacaaggtcct
gaaggcaccagaggtaatcctcagaattgcctatctggaaccaaactgaaaagcagtatt
cagaaagttaatgagtggttatccaggagtaatgacattttagcttctgattgctccctt
gacaagaatcataagcagaatgcagagatagctagtgccttagaagatgggcatccagat
aactctgatggaaattctagtatttctgagaagactgacgttgtggctgacactgccgat
gagacatggctacatatgcctgaaagaagttatcccaagccagcagaaaacaacaatatt
aaagataaaatatttggaaaaacctatcggagaaaatcgggtcaccctaatttgaatcac
ataactgaaaatttggttgttgagacagttgttcctgattctttggttcctccagaacct
ctgaaaaataccaagttaaagcgtaaaagaaagactatatgtgacttgcagcctgaggat
ttcatcaagaagacagttccaattactcacaaaacccctgaaaagaaacatgctgctgac
caaacctttgaaagagaacaaaatgaccaagtgatgaatatggataatggtcatcctgaa
cagaaagcactaaatggtcacgcaggggaaatgaaagaagctcagacatcagaactgttc
tctgcagagaaagaatccactctcagaactgaaacagagcctgcagctggcttaaatggt
ggagagaccaacataacaaaaaaagacaagccgaggaagcagccttcattcaaggttgtc
tgtgctcttgagcttggacatgatggaagcccaagctcttctaatgagactgaactacag
atcgatagctatcccagcagtgaagagataaggaaaaaaaaaaattctgaacagaaccaa
cttaggcgcagcagaaggcttcagcaggtatcagaagagattgcagttggagccaagaaa
gcccataagccagatgaccaagcagaagaaagttgtgtcactgaagttgtctcagaacta
aaattaggaaacgtatgtgcctgtgctcctgacaatctcagtaccgataaggatcaagta
ttagctagttgcagtttcacgggagatgaaaggagtctggaagtaatccctagcagccaa
gaccaagatttgtcattaagtggaagggaagagttacgaggtgaaagatctcaaggaagc
ctggggactgtggaggttcctgatactgcttgggacactcaggacagtacctcgttgttt
ccagctgatactcctcaaaattcaaaagcaggtcccagtcctcacagaagtcactgtgaa
ataatggaaataaaggaattcttagaaagtagttcatccaaaaacactgaaagtagtgca
gaagatttaaggagcccaatgaaacaagaagttaaaaatgcctccaagacaatcacagaa
atggaagatagtgaacttgacacccagtatttacagaatactttcaaacgttcaaagcgc
cagtcatttgcactgtgttctagcccaaggcaagaatatatgaaaacctgtgctgtccct
ggggctgtaagtcagcagagtacagttcatagataccaggagaaagaaaagcaagaaaac
agagaatcaaacaagcctgtgcagccaaagcctgctgtcatgaaagagaaggggaagcca
ggggatcatgccaaatgtagcaccagagaagtctccaggctttgtcgcatagcttcatta
aatagtgacaatgactgtgaacctattgctgaaatcagccagggaatttcacaagttcct
gatcaaaaacaatcagtttctccagcaagatcatttgatagtaaaatcatatatgcaaaa
aacttcctggaggaaaggcttgacggacaaaccacgtgccctgaaacagctatgggaaat
gaaagcttagcccaaagcagcattagtctaattagccaaagtaatagcagagaatatatt
tctaaaccaactgacttaattatcggcataggctctagtggagaaggcactcaggcagaa
aaaagtgaaaataaagaatctgaattaaatacaccacccaaattaaagcttatgcaaccc
caaatctctcaacagatctttcctcaggataattgcaaagggtataaaagaaaagggaag
ggaggaaatggaaaatcagctcaggccatcagtacagatttgtctccttatttagaacaa
actaaagagagtatacattcttctcaggtttggtctgagactcccgacttgttggacagt
gaaggcgaaataaaagaaaacactagctttgctgaaagtgacatcaacgaacaatctgct
atttttggcaaaattggtaaacgttttcaggtaaaacagtctagaaaaagccttagccct
ttcgtacatagaaatcccactttgactagaagagcccgaaaactggagtcctcagaagaa
gaagaggatgcctccagtgaagagggagaccttccaagttttcaagatttaatatttggc
aaagcagcaagtacaccctctcagcccaccaaaaataaaactatgggcttagagctttca
gcaaacaaagcaaaggaaaatccagacttctccctaaacagaaatagaatgaatgctagc
agtcctcagctatcatctagggaggcatcccaggatgataattccagccaagaatctgaa
tgttctggtagtttattttcttcacactctaactcattagaagacttaactggaaaagca
aatgacaaggattctgctttggtgtttgattcttctaaacaagggagaaatcagcccaga
acccaagaaatacagagtgctgatgatgtaccaaggatttctgaagatgaaggagaaagg
gaaattgatctagatgaagaccatcatctcaaagaccaaggtgtggactcaaatttaggt
aaatatgcatctggatatgatagtgaaacaagccatcctggagatatttcacagctatct
tctcagagtgatattttaactactcagcaaagagataccatgcaggacaacctgaaaaaa
cttcaacaggaaatggccgtcttagaagctgtcttggagcaacatggtagtcagacctcc
aacagccctctctctcaggaatccagactgtgcccttccatggaccagccagacttgaaa
cagaccagcacagaaaaaggagcagagaaaactgttgaatatcacgaaagccaaaattca
caaaacctttcgtcagacaagtcccaggcatttccaggggattccagcagcagtaaaaat
gaagaaccaggagttgaagggtcttcccttttagagaaccaaattctaaagggggtttgg
agcccacttggtcactccaggaatcttcagaaagtagactcctctttcagacaggggatt
gataggattactgccctgaaggaaaaacagcagtcaccacctgaggaacacaatgtaatg
atggaacagatttgtgtgctgaaaccaaacctcgaagcatctcctgagttagaatctgga
atcaaagtgtaccctgagaagaccaaatccagcccccaagagcataaggacactgcctta
agagatattctcaacctgcccacctcaacttctgcactaagacttcagactgggcaaagg
accaatccttctgctcctaatgctcctgcttggaatgggaaggggcccctggaggaggcc
tctgcctcaaagagtgtcaaaaaaggaggggcaggcagccccaaaatgtccctggtggca
tcgggtttgactcccaaagaacacatgttagtgcagaagtttgccaggaaaacccaaagc
acactatctaatcaaattactgaaggaaccactcatgtcataatgaaaacagatgctgag
tttgtatgtgagcggactctgaaatatttcttgggcattgcaggagggaaatgggtagta
agttttctgtgggtggtacagtcttttaaagaaggaaaggtgctgcctgagtgtgacttt
gaagtcagaggagatgtcatcaatggaagaaaccaccgaggcccagagagagcaagagaa
agccggggagtgaagatcttcaagggccttgaaatctgttgctatggaccatttacagat
atgtcaacagatcagctcgagtggatggtgcgactgtgtggggcttcggtggtgagaaag
ccttccttgttgagacccaggctgggttcttctccagttgtggttgtgcagcccgatgcc
tgggaagatgacagcagctttgagggaatcgggctgatatgcgaagcgcctgtagtgacc
cgggagtgggtgctggacagcatcgcctgttaccagcgccaggagctggacacctacttg
atagcccagacctcaggctgctgctga
DBGET
integrated database retrieval system
