Sarcophilus harrisii (Tasmanian devil): 100916865
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Entry
100916865 CDS
T02286
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.1
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04022
cGMP-PKG signaling pathway
shr04024
cAMP signaling pathway
shr04062
Chemokine signaling pathway
shr04071
Sphingolipid signaling pathway
shr04270
Vascular smooth muscle contraction
shr04310
Wnt signaling pathway
shr04360
Axon guidance
shr04510
Focal adhesion
shr04520
Adherens junction
shr04530
Tight junction
shr04611
Platelet activation
shr04670
Leukocyte transendothelial migration
shr04810
Regulation of actin cytoskeleton
shr04921
Oxytocin signaling pathway
shr05132
Salmonella infection
shr05135
Yersinia infection
shr05163
Human cytomegalovirus infection
shr05200
Pathways in cancer
shr05205
Proteoglycans in cancer
shr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100916865 (ROCK2)
04071 Sphingolipid signaling pathway
100916865 (ROCK2)
04024 cAMP signaling pathway
100916865 (ROCK2)
04022 cGMP-PKG signaling pathway
100916865 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100916865 (ROCK2)
04520 Adherens junction
100916865 (ROCK2)
04530 Tight junction
100916865 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100916865 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100916865 (ROCK2)
04670 Leukocyte transendothelial migration
100916865 (ROCK2)
04062 Chemokine signaling pathway
100916865 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
100916865 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100916865 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
100916865 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100916865 (ROCK2)
05205 Proteoglycans in cancer
100916865 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100916865 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
100916865 (ROCK2)
05135 Yersinia infection
100916865 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100916865 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100916865 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
shr03036
]
100916865 (ROCK2)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100916865 (ROCK2)
Protein kinases [BR:
shr01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
100916865 (ROCK2)
Chromosome and associated proteins [BR:
shr03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100916865 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
NPV_P10
APH
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
100916865
NCBI-ProteinID:
XP_012395611
Ensembl:
ENSSHAG00000012229
LinkDB
All DBs
Position
2:complement(113535620..113660923)
Genome browser
AA seq
1390 aa
AA seq
DB search
MSQPPAEKMSGTSEVVPWDWAFENRQRLLEALLWDPRSPIYVESLLDGITSLFFDLDFPA
LRKNKNIENFLIRYEKTVTKIRCLQMKAEDFDVIKVIGRGAFGEVQLVRHKASQNVYAMK
LLSKFEMIKRSDSAFFWEERDIMAFANSPWIVQLFCAFQDDRYLYMVMEYMPGGDLVNLM
SNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKNGHLKLADFGTCMKMDE
TGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVG
TYSKIMDHKNSLNFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHSFFKSDQWNW
DNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYSENLL
LGDAPSSSTENDSVQSRKNEQSVQIQKKLYLLEEHLKNEIQAKEDLDQKCKLVSTRLEKI
TKELEEEVTSRKNVESTLRQLEREKALLQHKNTEYQRKAEHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISNEQVNQLQRQLDEANALLRTESDTAARLRKNQTESSKQIQQLESNNR
ELQDKNCMLENAKLKLEKDFINLQSALESERRDRTHGSEMINDLQGRISGLEEDIKNGKI
SLAKMELEKRQLQERFTDLEKEKSNMEIDMTYKLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKVNELLK
QKDKLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQMKQENNHLMEIKMS
LEKQNIELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECQEKTKLCKEMQQK
SQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LAEKDATIASLEEANRTLTSDVANLANEKEELNNKVKEVQEQISRLKDEETNISVIKTQF
EKQLLNERTLKTQAVNKLAEIMNRKEPPRRGADTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
EAEADDGFPGTESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYM
VLDIDKLFHVRPVTQTDVYRADSKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNCICH
KGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVY
YDISSAKNLLLLANSTEDQQKWVSRLIKKIPKKPPAPDPFARSSPRTSMKVQPNQSIRRP
SRQLPPSKPS
NT seq
4173 nt
NT seq
+upstream
nt +downstream
nt
atgagccagccgccggccgagaaaatgtctggcacgtcggaggtagtgccgtgggactgg
gccttcgagaaccgccagcggctgctggaggctctgctctgggacccccgctcccccatc
tacgtggagagcctcctggatggcataacttccttgttctttgatttggattttcctgct
ctgaggaaaaacaagaatatagaaaatttcttaattagatatgaaaaaactgtgacaaaa
attagatgcctacagatgaaggcagaagattttgatgttattaaagttattggaagaggt
gcttttggtgaagttcagttggttcgtcataaagcatcacaaaatgtttatgccatgaag
cttcttagtaaatttgaaatgataaaaagatcagattctgctttcttttgggaagaacga
gatatcatggcttttgccaatagtccctggattgttcagctcttttgtgcctttcaagat
gatagatatctttatatggtaatggaatacatgcctggtggagaccttgtaaatcttatg
agtaactatgatgtacctgaaaaatgggccaaattttatacagctgaagttgttctggct
ttggatgcaatacactccatgggtttaatacacagagatgtgaagcccgacaacatgctt
ttagataaaaatggacatctgaaattagcagattttggcacttgtatgaaaatggatgaa
acaggaatggtacgttgtgatacagcagttggaacacctgattatatatcacctgaagtt
ctgaagtcacaaggtggtgatggctactatggacgagagtgtgattggtggtctgtgggt
gttttcctttttgagatgcttgttggggacactccattttatgcagattcacttgtggga
acatatagtaaaatcatggatcataaaaattcactaaattttccagaagatgcagaaata
tccaagcatgcaaagaatctcatatgtgctttcttgactgatagggaggtgcgacttggg
agaaatggggtagaagaaatcaaacagcactctttctttaaaagtgatcagtggaattgg
gataacataagagaaactgcagctccagtagtacctgaactcagcagtgacatagatagc
agcaattttgatgacattgaagatgataaaggagatgtggaaacctttccaattcctaaa
gcctttgtgggaaatcaactgccttttataggttttacctattatagcgaaaatttgtta
ttaggtgatgctccttcttccagtacagaaaatgattcagtacaatcaaggaaaaatgag
caatctgtacagattcaaaaaaaactatatttattagaagaacacctcaaaaatgagata
caagccaaagaggatctggaccagaagtgcaaattggttagcactcgactagagaagata
acaaaagaactagaagaagaggtaacctcaagaaagaatgtagaatctacattaagacaa
ttggaaagagagaaggctcttcttcaacacaaaaatacagaatatcagcggaaggcagaa
catgaagcagacaaaaaacggaatctggaaaatgatgttaacagtttgaaagatcagctt
gaagatttgaaaaaaagaaatcaaaactctcaaatatctaatgaacaagtcaatcagctc
caaagacaattggatgaagccaatgctttgctgcgaactgagtctgatactgcagccagg
ttacggaaaaaccagacagaaagttcaaaacaaattcagcagctggaatctaataatagg
gagttacaagacaaaaattgcatgctagagaatgctaaactgaaacttgaaaaggacttc
atcaatcttcagtcagctctagaatcagaacggagagatagaacccatggatctgagatg
attaatgatttacaaggtagaatatctggtttggaagaagatattaaaaatggtaaaatt
tcattagcaaaaatggaattagagaagagacaactacaggagagatttacagatttagaa
aaggaaaaaagtaatatggaaatagacatgacatacaaactgaaagttatacaacaaagc
ttggaacaggaagaagcagaacataaagctacaaaagcacggttagcagataagaataag
atatatgaatctatcgaggaggctaagtctgaagctatgaaggaaatggagaagaaactc
ctagaggaaagaactttaaagcaaaaggtggaaaaccttctcttggaagccgaaaaaaga
tgttcactgttagactgtgatctcaaacagtcccaacagaaagtcaacgaactcttaaaa
cagaaggacaaactgaatgaagatgtcaggaatttgaccttaaaaatagaacaagaaaca
caaaagcgctgcctcacacaaaatgacctgaagatgcaaacacaacaagtcaacacactg
aaaatgtctgaaaaacaaatgaaacaagaaaataatcatcttatggaaatcaaaatgagt
ctggaaaagcaaaatattgaacttcggaaagaacggcaagatgcagatggacaaatgaaa
gagctccaagatcagcttgaagcagaacaatatttctcaactctgtataaaacacaagtt
cgagagcttaaagaagaatgtcaagagaagaccaagctttgcaaagaaatgcagcagaag
agccaggaattacaggatgaaagggactccttggctgcgcaacttgagatcaccttgaca
aaagctgattcagaacagctagctcgttctattgctgaagagcagtattctgatttggaa
aaagaaaagatcatgaaagagttggaaattaaagagatgatggcgcgacacaaacaagaa
cttgcagaaaaagatgctacaatagcatctcttgaggaggctaataggacactaactagt
gatgtggctaatcttgcaaatgagaaggaagaactgaataataaagttaaggaagtccaa
gagcaaatctcaaggttgaaagatgaagaaacaaatatatcagttattaaaacacaattt
gagaaacaactattaaatgagagaacactgaaaactcaggctgtgaataaattggctgag
attatgaatcgaaaagaacctcccaggcgtggtgctgacacagatgtgagaaggaaagag
aaggagaacagaaagctgcatatggaactaaaatcagaacgtgaaaaattaactcagcaa
atgatcaaatatcagaaagaattaaatgaaatgcaagctcaaatagctgaagaaagccaa
attcgaattgaattgcaaatgacgctggacagtaaagacagtgatattgaacagcttcga
tcacaactccaggccttgcatattggcctggatagttccagtataggcagtggaccagga
gaagctgaggcagatgatgggttcccaggtacagaatcaagattagagggatggctttca
ttgcccgtacgaaacaatacaaagaagtttggatgggttaaaaagtatgtaattgtaagc
agcaagaagattcttttctatgatagtgaacaagataaagaacagtctaatccctacatg
gtgttagatatagacaagttgttccatgtcaggccagtcacacagacagatgtttataga
gctgattccaaagagattccaaggatattccagattctgtatgctaatgaaggggaaagc
aaaaaagaacaagaatttcccgtggaaccagttggggagaagtcaaactgcatctgtcac
aaaggacatgaatttattcccactctttatcatttcccaactaactgtgaagcctgtatg
aagccactttggcacatgtttaaacctccacctgctcttgaatgccgccgctgccatatc
aaatgccataaagaccacatggacaaaaaggaggaaatcatagcaccttgcaaagtatac
tatgacatttcatcggcaaagaatctgctgttattagctaattctacagaggaccagcag
aagtgggttagtcggttaataaaaaagatacctaagaaacccccagcaccagatcctttt
gctcgatcatctcctagaacttctatgaaggtacagcctaaccaatctataagacggcca
agtcgacagcttcctccaagcaaaccaagctaa
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integrated database retrieval system
