Sarcophilus harrisii (Tasmanian devil): 100917212
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Entry
100917212 CDS
T02286
Symbol
PDGFRB
Name
(RefSeq) platelet-derived growth factor receptor beta
KO
K05089
platelet-derived growth factor receptor beta [EC:
2.7.10.1
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr04010
MAPK signaling pathway
shr04014
Ras signaling pathway
shr04015
Rap1 signaling pathway
shr04020
Calcium signaling pathway
shr04072
Phospholipase D signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04510
Focal adhesion
shr04540
Gap junction
shr04630
JAK-STAT signaling pathway
shr04810
Regulation of actin cytoskeleton
shr05165
Human papillomavirus infection
shr05200
Pathways in cancer
shr05206
MicroRNAs in cancer
shr05214
Glioma
shr05215
Prostate cancer
shr05218
Melanoma
shr05230
Central carbon metabolism in cancer
shr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100917212 (PDGFRB)
04014 Ras signaling pathway
100917212 (PDGFRB)
04015 Rap1 signaling pathway
100917212 (PDGFRB)
04630 JAK-STAT signaling pathway
100917212 (PDGFRB)
04020 Calcium signaling pathway
100917212 (PDGFRB)
04072 Phospholipase D signaling pathway
100917212 (PDGFRB)
04151 PI3K-Akt signaling pathway
100917212 (PDGFRB)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100917212 (PDGFRB)
04540 Gap junction
100917212 (PDGFRB)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100917212 (PDGFRB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100917212 (PDGFRB)
05206 MicroRNAs in cancer
100917212 (PDGFRB)
05230 Central carbon metabolism in cancer
100917212 (PDGFRB)
05231 Choline metabolism in cancer
100917212 (PDGFRB)
09162 Cancer: specific types
05214 Glioma
100917212 (PDGFRB)
05218 Melanoma
100917212 (PDGFRB)
05215 Prostate cancer
100917212 (PDGFRB)
09172 Infectious disease: viral
05165 Human papillomavirus infection
100917212 (PDGFRB)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100917212 (PDGFRB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100917212 (PDGFRB)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
shr04090
]
100917212 (PDGFRB)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100917212 (PDGFRB)
Protein kinases [BR:
shr01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
100917212 (PDGFRB)
CD molecules [BR:
shr04090
]
Proteins
100917212 (PDGFRB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
Ig_3
I-set
ig
Ig_2
V-set
VEGFR-1-like_Ig-like
VEGFR1-3_N_Ig-like
C2-set_2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100917212
NCBI-ProteinID:
XP_031809371
Ensembl:
ENSSHAG00000017061
UniProt:
G3WXF6
LinkDB
All DBs
Position
2:complement(382129551..382198186)
Genome browser
AA seq
1092 aa
AA seq
DB search
MLPVLSAWLWLVLLLEVEALKITPHGSEFVLNISSTFVLTCTGDSPVVWEKTPQQTPPPV
LEAQDGTFSSILTITNVTGLDTGEYICSYNGSQGLEFGGQKRVYIFVPDSSVGFLPVDPE
ELFIFFTGDSETTIPCRVTDPKLVVTLHEKKVDISLPVAYDHQRGFTGPFEDKTYICKTI
IDEREVDSDAYYVYRIQVSSINVSVNAVQTVVRKGENITVLCIVKGNEVVNFDWTYPRME
SKRLVEPVTDFLSGLEYDIRSILHIPSAELGDSGTYVCNVSESYNGHRDMKGVNVTVVDK
GFVRFLGELDELEFAELHKSRTLQMFIEAYPAPTIVWLKDNQTLGSGTASEISISTRNLS
ETRYVSELTLVRVKVNEGGYYTLRAFHDDAADSFSFQLQINVPAKVMDLSESHPSSGEQL
LTCRSQGMPQPILNWFSCSDFKRCPRDVLPTPLGNSSKEETQLETNVTYWEQEKLFEVVS
ILRLQRVDQPLSVICDVYNLLGRDSKEVTIVPHSLPFKVVVISAILALVVLTIISMIILV
ILWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSSWELPRERLVLGRTLGSGAFGQ
VVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNIVNLLGACTK
GGPIYIITEYCRYGDLVDYLHRTKHTFLQHCPEKGGSYQCSEVLNPPDHQLHRQTSLSGE
SDGGYMDMRKDDCVDYVPMLGMKGEIMYVDIESSNYSSPYDSFAPSVPERSYRATLINDS
PILSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDS
NYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYN
AIKRGYRMAKPTHASEEIYEIMQKCWEEKFEIRPSFSQLVILMEGLLGEGYKKKYQQVDE
EFLRSDHPAILRTRAQLPTFGGPRGPLDTSSVLYTAVQQNEGDNDYIIPLPDPKPEGPEA
APLESSHSLASSTLNEVNTSSTISCDSPLELQEELEPEPEEPELEPKPEPQLEPEPEPSP
GPGQQEVEDSFL
NT seq
3279 nt
NT seq
+upstream
nt +downstream
nt
atgcttcctgttctctcagcttggctgtggctggtgttattgcttgaggtggaggcactg
aagataaccccccatggctcagagtttgttctgaacatctccagcacctttgtcctgact
tgcacaggggattccccagtggtctgggaaaagactccccagcagaccccaccacctgtt
cttgaggcccaagatggcaccttctccagcatcttgaccatcaccaacgtcactggtctt
gacacaggagagtacatatgttcctacaatggctcccaaggcttagagtttggtgggcag
aagcgggtctacatctttgtgccagattcctctgtgggtttcctccctgtggatcctgaa
gagctgttcatcttcttcacgggagacagtgagaccacaatcccgtgtcgagtgactgac
cccaaactggtggtaacgttgcatgagaagaaggtggacatatccctgcctgttgcctat
gaccaccagcgtggattcaccggcccctttgaggacaagacctacatctgcaaaaccatc
attgatgagagggaggtagactctgacgcttattatgtctaccgcatccaagtctcatcc
atcaatgtctctgtgaatgcagttcagactgtggtgcggaagggtgagaacatcactgtg
ctctgcattgtgaagggtaatgaagtggtgaactttgactggacttaccctcgaatggag
agtaagcggctggtggagccagtgacagatttcctttcggggttagagtatgacatccgc
tccatcctgcatatccccagtgccgagctgggagattctggtacctatgtctgcaatgtc
tcagagagttacaatggccacagggacatgaaaggagtcaacgtcacagtggtggacaaa
gggtttgtgagatttctgggggagttggatgagctggagtttgctgaactgcacaaaagt
cgaaccctacagatgttcatcgaagcgtaccctgcacccaccattgtgtggctcaaggac
aaccagactttgggctctggaactgccagtgagatctctatctccaccaggaatttgtct
gagacgaggtatgtgtcagagctgaccttagtacgagtaaaggtgaatgaagggggttat
tataccctcagagccttccatgatgatgctgctgactcgttctccttccagttgcagatc
aacgttcccgctaaggtgatggatctgagtgagagccaccccagcagtggggagcaactc
ctcacttgccgaagtcaggggatgccacagccaatcctcaactggttcagttgcagtgat
tttaagaggtgtccccgcgatgttctgcctaccccactggggaacagctccaaggaggaa
actcagttggaaaccaatgtgacctactgggagcaagagaaattgtttgaggtagtcagc
atcctgcgcttgcaacgtgtggaccagcccctctctgtcatctgtgacgtgtacaacctc
ctggggagagacagcaaggaagtcaccattgttccacattccctgcccttcaaggtggtt
gtgatttcagccatcctggccttagtggtcctcacaatcatctccatgatcatccttgta
attctgtggcagaagaaaccccgctatgagatccgctggaaggtgattgaatctgtgagc
tcggatggtcatgaatacatctacgtggatcccatgcaattgccctatgactccagctgg
gaactgccccgagagcggcttgtgcttggtcgtacacttggttctggagcctttgggcaa
gtagtggaggccacagcccatggactaagccactcccaggccacaatgaaggtggctgtc
aagatgctaaaatccaccgcccggagcagtgagaagcaggcccttatgtctgaattgaag
atcatgagccacctggggccccacctgaacattgtcaacctgctgggggcgtgcactaaa
ggaggccccatctacatcatcacagaatactgccgttatggagatctcgtagactatcta
catcgaaccaagcacacgttcttgcagcattgtcctgagaaaggagggtcttaccagtgc
tcagaggtcctgaaccctcctgaccatcagctgcacagacaaacatcgctatcgggggag
agtgacggaggctacatggacatgaggaaggatgactgtgtggactatgtcccaatgctg
ggcatgaagggagagatcatgtatgtggatattgaatcctccaactacagctcgccctat
gatagctttgcaccctctgttccagagagatcctacagagccaccctgatcaacgattcc
cctatcctcagttacatggaccttgtgggcttcagttaccaggtggccaatggcatggag
ttcctggcttccaagaattgtgtccatcgagacctggcagccaggaacgtgctcatctgt
gagggtaaacttgtcaagatctgtgactttggcctggcccgggacatcatgcgtgactcc
aactacatctccaaaggcagtactttcctgcccttgaagtggatggctccagaaagcatc
ttcaacagcctgtacaccaccctgagtgatgtgtggtccttcggcatcctcctctgggag
atcttcaccctgggtggcaccccttatccagagttgcccatgaatgagcagttctacaat
gccatcaagcgtggctaccgcatggccaaacccactcatgcctctgaagagatctatgaa
atcatgcagaagtgttgggaggagaaattcgaaattcgaccctccttctctcaattggtc
attctgatggagggccttctgggggagggctacaagaagaagtaccagcaagttgatgaa
gaatttttgagaagcgaccacccggccattctgcgcacccgagcccagctccctacattt
ggtggcccgaggggcccccttgacaccagctctgttctctacacggccgtgcagcagaat
gaaggggacaatgactacatcatccccctgccagaccctaagcctgaaggacccgaggca
gccccactggagagttcccacagtctcgccagctctaccctgaatgaagtcaacacatca
tccaccatctcttgtgatagtcccctggagcttcaagaagaactagagcccgagccagag
gagccagagctggagccgaagccagagccacagctggagccagagccagagcccagcccg
ggcccggggcagcaggaggtggaggatagcttcctgtag
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