KEGG   Sarcophilus harrisii (Tasmanian devil): 100919158
Entry
100919158         CDS       T02286                                 
Symbol
MTR
Name
(RefSeq) methionine synthase isoform X1
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00270  Cysteine and methionine metabolism
shr00450  Selenocompound metabolism
shr00670  One carbon pool by folate
shr01100  Metabolic pathways
shr01230  Biosynthesis of amino acids
shr04980  Cobalamin transport and metabolism
shr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:shr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    100919158 (MTR)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    100919158 (MTR)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100919158 (MTR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100919158 (MTR)
   04980 Cobalamin transport and metabolism
    100919158 (MTR)
Enzymes [BR:shr01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     100919158 (MTR)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-GeneID: 100919158
NCBI-ProteinID: XP_012403400
Ensembl: ENSSHAG00000002966
LinkDB
Position
4:373557484..373671526
AA seq 1263 aa
MPPTLEEPRPPGKRILKNDIEAILKEKIMVLDGGMGTMIQRYTLSEEDFRGQDLKNHAKP
LKGNNDLLSITQPDIICKIHKEYLMAGADIIETNTFSSTWVAQADYGLEHLAYRLNKCSA
EVARKAADDVTSQTGIKRFVAGSMGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQARG
LLDGGVDILLVETIFDTANAKAALFALQKLFEEEYDRRPIFVSGTIVDKSGRTLSGQTGE
AFVISVSHAEPLCLGLNCALGALEMRPFIETIGKCTTAYVLCYPNAGLPNTFGEYDETPE
MTAMHIKNFALDGLVNVVGGCCGTTPDHIREIAEAVKNCKPRVPPASIFDGYMLLSGLEP
FRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKTQVEMGAQILDINMDDGML
DGPSAMTRFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFL
AKAKKIKMYGAAVVVMAFDEVGQATETSNKIEICTRAYHLLVKKVRFNPNDIIFDPNILT
IGTGMEEHNLYAVNFINATKTIKETLPGAKISGGLSNLSFSFRGMEAIREAMHGVFLYHA
IKFGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPDATEKLLRYAQTQAKGGKKTIQ
TDEWRNGPIEERLEYALVKGIEKYIVEDTEEARMNKEKYPRPLNIIEGPLMNGMKVVGDL
FGAGKMFLPQVIKSARVMKKAVGYLIPFMEKERAEKRALTGNVEEEDPYQGTIVLATVKG
DVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILRAAIDNKADIIGLSGLITPSLDEMIF
VAKEMERLDIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLK
EDFFEEIIEEYEDIRQDHYESLKERRYLTLDQARKKGFHIDWLSESAPVKPRFIGTQVFE
DYDLQRLADYIDWKPFFDVWQLRGRYPNRGFPKIFNDKTVGEEAKKLYDDAQNMLKVLIS
EKKLQARGLVGFWPAQSVQDDIHLYAEDAVPQSAEPIATFYGLRQQAEKDSASTDPYYCL
SDFIAPLESGVRDYLGFFAVACFGVDELSKSYEEQCDIYSSIMVKALGDRLAEAFAEELH
ERVRKELWAYSDSEQLDVADLRRIRYGGIRPAPGYPSQPDHTEKLTMWKLGHIEETTGIR
LTESLAMAPASSVSGLYFANLKSKYFSVGKISKDQIEDYALRKNMSVDEVERWLGPILGY
DAD
NT seq 3792 nt   +upstreamnt  +downstreamnt
atgccgcccactctggaagaaccgcggccgccgggaaaaagaattctgaagaatgatatt
gaagccattttgaaggagaagatcatggtattggatggtggtatggggaccatgatccag
aggtatacattgtctgaagaggacttcagaggacaggacttgaaaaaccatgccaaacct
ttgaaaggcaacaatgatctcttaagtataacgcagcctgatattatttgcaagatccat
aaggagtacttgatggctggagcagatattattgaaacaaatacttttagcagcacttgg
gttgcccaggctgactatggccttgaacacttggcttatcggctgaataaatgttctgca
gaagtggctagaaaggcagctgatgatgtaacttctcagacagggattaagagatttgta
gcagggtccatgggtcccaccaataagaccctctctgtgtccccttctgtggaaagaccg
gattacagaaacatcacctttgatgaactagttgaagcttaccaagagcaggccagagga
cttctagatggtggagttgacatcttattggtagaaactatttttgatactgcgaatgct
aaggcagccttgtttgcactccagaaactctttgaagaggaatatgatcggcggcctatc
tttgtttcaggtactattgtggataagagtgggcgaactctttctggacaaacaggagag
gcatttgtcatcagcgtttcccatgcagaaccactatgccttggattaaactgtgcttta
ggagccctggaaatgagacctttcattgaaacaattggcaagtgtacaacagcatatgtc
ctctgttatcccaatgcaggtcttcccaatacctttggcgagtatgatgaaacacctgaa
atgactgcaatgcatataaagaactttgcattggatggtttggtcaatgttgtaggtggt
tgttgtggtaccacgccggatcatatcagggaaattgcagaagctgtgaaaaattgtaaa
cctagagttccccctgcatctatttttgatggatatatgttgctgtcaggactagagcct
ttcaggattggaccatacaccaactttgttaacattggtgaacgctgtaatgttgcggga
tcgaagaagtttgctaaactcatcatggcaggaaactatgaagaagctttgagtgtggct
aaaacccaagtggagatgggagctcagattctggatattaacatggatgacgggatgttg
gatggccccagcgcgatgaccagattttgtaacttcattgcttctgaacctgatattgct
aaggtaccattatgtattgactcttctaattttgctgtgatagaggctggcttgaaatgc
tgccaggggaagtgtattgtcaacagcattagtctgaaggaaggcgaggatgactttctg
gcgaaggcaaagaagatcaagatgtatggggctgctgtggtggtcatggcatttgatgaa
gtgggtcaagctacagaaaccagcaataaaattgaaatatgtacacgtgcctaccatctt
cttgttaaaaaagtgaggtttaaccccaatgacatcatctttgaccccaatatccttact
attgggacaggaatggaagagcataatttgtatgctgttaactttatcaatgcaactaaa
actatcaaggaaacattacctggagccaaaataagtggaggcctttccaacctgtccttc
tccttcagaggaatggaagctattcgagaagccatgcatggggtttttctttaccatgca
ataaagtttggaatggacatgggaatagtgaatgcaggaaacctcccggtgtatgatgac
atccacaaagaactcctccagctttgtgaagatctgatttggaataaggacccagatgca
acagagaagctgttacgctatgcccagactcaggccaaaggaggaaagaaaactattcag
acagatgaatggcggaatggccctatcgaggaaagactggagtatgccctagttaagggc
attgaaaaatatattgtagaggacactgaggaagcaagaatgaacaaggaaaaatatccc
cgaccactgaacataatcgaagggcctttgatgaatggcatgaaagtagttggggatctc
tttggtgctggaaagatgtttcttccacaggtaataaagtcagcccgtgtcatgaagaag
gcagttggctatcttattcctttcatggaaaaagaaagagcggaaaaaagggctcttact
ggaaatgtggaagaagaggacccttatcaaggcaccattgtgttggcgactgtcaagggt
gatgtgcatgacataggcaagaacattgtaggtgtagtcctgggctgtaataatttcagg
gttattgatttaggagtcatgactccctgtgataaaatattgagagccgctattgacaac
aaagcagatataattggcctgtcaggactcatcactccctctctggatgaaatgattttt
gttgccaaggaaatggagagattagatataaagattcctttgttgattggaggagcaacc
acttccagaacccatacagcagttaaaatagcaccaagatatagtgctcctgtaatacat
gtcctggatgcatccaaaagtgtggtggtgtgctcgcagctattggatgaaaatctaaag
gaagacttctttgaggaaatcattgaagagtatgaagacattaggcaggaccattatgaa
tctctcaaggaaagaagatatttaactttagatcaagcccggaaaaaaggattccatata
gactggctctcagaatcagctccagtgaagcccaggtttattgggactcaggtatttgaa
gactatgacttgcagaggctggccgactatattgactggaaacctttcttcgatgtctgg
caactcaggggccgataccccaatcgaggctttcccaagatctttaatgacaaaacagtg
ggggaagaagccaaaaaattgtatgatgatgcccaaaatatgttgaaggtactgattagt
gaaaagaaactacaagccaggggtttggttggattctggccagcacagagtgtccaggat
gatattcatttgtatgcagaagatgctgtaccacaatctgcagagccaatagctacattt
tatggcttaagacaacaggcagaaaaggactctgcaagcacagacccttattattgcctg
tctgactttattgctcctttggaatctggagtccgtgactacttgggcttctttgctgtg
gcctgctttggagtagatgaactgagcaagagctatgaggagcaatgtgacatctacagc
agcatcatggttaaagctctgggagaccggttggcagaggcttttgcagaagaacttcat
gaaagggttcgcaaagaattgtgggcttacagtgacagtgagcagctagatgttgctgac
ctgcggagaatccggtatgggggcatccgccctgctcctggctatcccagccaacctgac
cacactgagaagctcacaatgtggaaactcggccacattgaagaaactacaggaatcaga
cttacagaatcattagcaatggcgccagcttcatccgtttctggtctctactttgccaat
ctgaagtccaaatatttttctgttggtaaaatttccaaggaccagattgaagattatgct
ttgaggaaaaacatgtctgtggatgaagttgagagatggctgggacccattttgggatat
gatgcagactaa

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