Sarcophilus harrisii (Tasmanian devil): 100919889
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Entry
100919889 CDS
T02286
Symbol
IDE
Name
(RefSeq) insulin-degrading enzyme isoform X1
KO
K01408
insulysin [EC:
3.4.24.56
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr03266
Virion - Herpesvirus
shr05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03266 Virion - Herpesvirus
100919889 (IDE)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100919889 (IDE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
shr01002
]
100919889 (IDE)
Enzymes [BR:
shr01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.56 insulysin
100919889 (IDE)
Peptidases and inhibitors [BR:
shr01002
]
Metallo peptidases
Family M16: pitrilysin family
100919889 (IDE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M16_M
Peptidase_M16_C
Peptidase_M16
PqqF-like_C_4
Tn916-Xis
PqqF_C_3
Motif
Other DBs
NCBI-GeneID:
100919889
NCBI-ProteinID:
XP_031811912
Ensembl:
ENSSHAG00000018317
UniProt:
A0A7N4NTG6
LinkDB
All DBs
Position
2:complement(586385113..586489445)
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AA seq
1019 aa
AA seq
DB search
MRYGLAWRLLHPALRTTFLPVLTARLCGEHLSGFQRGTCGKMDNPAVKRIVNHIIKSPED
KREYRGLELINGIKALLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHKHLEGALDRFAQFFLCPLFDESCKE
REVNAVDSEHEKNVMNDAWRLFQLEKATGNPNHPFSKFGTGNKYTLETRPTQEGIDVRQE
LLKFHSTYYSSNLMAICVLGRESLDELTELVVKLFSEVENKNVPLPEFPEHPFQEEHLRQ
LYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRTEGPQEWVFQECKDLNAV
AFRFKDKERPRGYTSKIAGILHYYPLEEVLAAEYLLEEFRPDLIEMVLDKLRPENVRVAI
VSKSFEGQTDQTEEWYGTQYKQEAIPDEVIEKWKNADLNGKFKLPTKNEFIPTNFEILPL
EKEATSYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
SRLHIEALLHGNIAKQAALGVMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
NGIQGLRFIIQSEKPPHYLESRVEAFLLSMEKSIEDMNEEAFQKHIQALAIRRLDKPKKL
SAECAKYWGEIISQQYNFDRDNTEVAYLKTLSKDDIIKFYKEMLAVDAPRRHKVSVHVLA
REMDSCPVVGEFPCQNDVNLTQAPALPQPEVIENMTEFKRGLPLFPLVKPHINFMAAKL
NT seq
3060 nt
NT seq
+upstream
nt +downstream
nt
atgcggtacgggctagcgtggcggctgctgcaccccgcgctccgcacgaccttcctcccc
gtcctcaccgctcgcctctgcggggagcatctttcgggctttcagagagggacttgcggc
aaaatggataaccctgctgttaaaagaatagtcaatcatattatcaaatctccagaggat
aaacgagaataccgtggattagagttgataaatggcatcaaggcactcctcatcagtgat
cctaccacagataagtcatcagcagctcttgatgtacacataggatcattatcagatccc
ccaaatattgctggtttaagccatttttgtgaacatatgctcttcttgggaacgaagaaa
tatccaaaagaaaatgaatatagccaattcctcagtgagcatgcagggagttcaaatgct
ttcacaagtggagaacataccaactactactttgatgtatcacataaacacctggaaggg
gccctggacagatttgcccagtttttcttgtgtcctttgtttgatgagagctgcaaagag
agagaggtgaatgcagttgattcggaacatgagaagaacgtaatgaatgatgcctggaga
ctgtttcagctggagaaagctacaggaaaccccaaccatccctttagtaaatttggaaca
ggtaacaaatataccttggaaacaagaccaacccaagaaggcattgatgtaagacaagaa
ttactgaaattccattctacttattactcatccaacttaatggctatttgtgtgctggga
cgagaatcactagatgagttgaccgaactagttgtgaagttattttcagaagtagagaac
aaaaatgtcccactaccagaatttccagaacaccctttccaagaagagcatcttaggcaa
ctttacaaagttgtacccattaaggacatcagaaatttatatgttacatttccaatacct
gatcttcagaaatattataagtcaaaccctggtcattatcttggtcatcttattggacat
gaaggccctggaagtctcttatcagaactcaaatcaaaggggtgggtaaacactcttgta
ggaggtcaaaaggaaggagccagaggctttatgtttttcatcattaatgtggatttgaca
gaggaaggacttttacatgttgaagatataattttgcacatgtttcaatacattcagaag
ttacgtacagaaggacctcaagaatgggttttccaagagtgcaaggatttgaatgctgtt
gcttttaggtttaaagataaagagagacctagaggttatacatctaaaattgcaggaata
ttgcattactatcctctagaagaagtgcttgcagcagaatatttgctagaagaatttcgc
cctgatttaatagagatggttcttgataaactgaggccagaaaatgttcgggttgcaata
gtttccaagtcttttgaaggacaaacagatcaaacagaagagtggtatggaacacagtat
aaacaggaggctataccagatgaggtcattgagaaatggaaaaatgctgacttaaatgga
aagtttaagcttccaacaaagaatgaatttattcctacaaattttgagatcttgccgcta
gaaaaggaagcaacatcgtaccctgctctcattaaggacacggccatgagcaaactctgg
tttaaacaagatgataaatttttcttgccaaaagcttgtctcaactttgaatttttcagc
ccatttgcttatgtggatcccttgcactgtaacatggcctatttgtaccttgagctcctc
aaagactccctcaacgagtatgcatatgcagcagagcttgctggcttgagctatgacctc
caaaataccatctatgggatgtatctctctgtaaaaggatacaatgacaagcagcctatt
ttgctaaagaagattattgagaaaatggccacttttgagattgatgaaaaaagatttgaa
attatcaaggaagcgtatatgcgctcgcttaacaactttcgagcggaacagcctcaccag
catgctatgtattatctccgactgttaatgactgaagtggcctggaccaaagatgaacta
aaagaagctctagatgatgttactctccctcgccttaaggcctttatacctcaactcttg
tcacggttacatatcgaagcccttcttcatggaaatatagcaaaacaggctgcattagga
gttatgcagatggttgaagacacactcattgaacatgctcatactaaacctctccttcca
agtcagcttgtacgataccgagaagttcaactccccgataggggctggtttgtttatcag
cagagaaacgaagttcacaataactgtggtattgaaatttattaccaaacggatatgcag
agtacctcagagaacatgtttttggagctcttctgccagatcatctcagagccttgcttc
aatactctgcgtaccaaggagcagctaggttacattgtatttagtggtccccgtcgagcc
aatggcatccaaggtcttcgatttatcatccaatctgaaaaaccacctcactatttagaa
agcagagtggaagctttcttgttatccatggaaaaatctatagaagacatgaacgaggag
gccttccagaaacacattcaagccttagcgatccgtcggctagataaaccaaagaaactg
tctgcagagtgtgctaaatattggggagaaatcatctctcagcagtataattttgaccga
gataacacagaagttgcatatttaaagacacttagtaaagatgatatcatcaagttttat
aaggaaatgttggctgtagatgcccccaggaggcacaaggtatccgtacatgttcttgcc
agggaaatggattcctgtcctgttgttggagagtttccatgtcagaatgatgtaaatttg
acacaagctccagccttaccccaaccagaagttatcgaaaacatgacggaattcaagcgg
ggtctgccactgtttcccctcgtgaaaccacatataaatttcatggctgcaaaactctga
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