KEGG   Sarcophilus harrisii (Tasmanian devil): 100920096
Entry
100920096         CDS       T02286                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00670  One carbon pool by folate
shr00790  Folate biosynthesis
shr01100  Metabolic pathways
shr01240  Biosynthesis of cofactors
shr01523  Antifolate resistance
shr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:shr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100920096 (DHFR)
   00670 One carbon pool by folate
    100920096 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100920096 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100920096 (DHFR)
Enzymes [BR:shr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100920096 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 100920096
NCBI-ProteinID: XP_031822854
Ensembl: ENSSHAG00000016538
UniProt: G3WVM0
LinkDB
Position
1:complement(171292588..171324546)
AA seq 187 aa
MVRPINCIAAVSQNMGIGKNGDLPWPPLRNEFNYFQKMTTTSSVEGKQNLLIMGKKTWFS
IPEKHRPLKDRINLVLSRELKEPPPGAHYLAKSLDDALDLLELPELADKVDMIWVIGGSS
VYKEAMEKPGHQRLFVTRILQEFECDTFFPEIDLKKYKLLPEYPGVLTDIQEEKGIQYKF
EVYEKHD
NT seq 564 nt   +upstreamnt  +downstreamnt
atggtgcgtccgatcaactgcatcgcggccgtgtcccagaacatgggcatagggaagaac
ggggacctgccgtggcccccgctcaggaatgaattcaactacttccagaagatgactaca
acttcttcagtagaaggtaaacagaatctgttgataatgggaaagaaaacctggttctcc
attcctgagaagcatcgacctttgaaagataggattaacttagttctcagtagagaactg
aaagaacctcctcctggagctcattatcttgccaaaagtctggatgatgcattagacctt
cttgaacttccagaactagcagataaagtggacatgatttgggtaattggaggcagctct
gtttataaggaagcaatggagaaacctggtcatcagcgactgtttgtgacaagaattttg
caagaatttgagtgtgatacattttttccagaaattgatctaaagaaatataaacttctc
ccagaatatccaggtgttcttactgatatccaggaagaaaaaggcattcagtataaattt
gaagtatatgaaaaacatgattaa

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