Sarcophilus harrisii (Tasmanian devil): 100922118 Help Entry 100922118         CDS       T02286                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr04064   NF-kappa B signaling pathway shr04380   Osteoclast differentiation shr04650   Natural killer cell mediated cytotoxicity shr04658   Th1 and Th2 cell differentiation shr04659   Th17 cell differentiation shr04660   T cell receptor signaling pathway shr05135   Yersinia infection shr05166   Human T-cell leukemia virus 1 infection shr05235   PD-L1 expression and PD-1 checkpoint pathway in cancer shr05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100922118 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100922118 (LCK)    04660 T cell receptor signaling pathway     100922118 (LCK)    04658 Th1 and Th2 cell differentiation     100922118 (LCK)    04659 Th17 cell differentiation     100922118 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     100922118 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100922118 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100922118 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     100922118 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     100922118 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:shr01001]     100922118 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:shr03036]     100922118 (LCK) Enzymes [BR:shr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100922118 (LCK) Protein kinases [BR:shr01001]  Non-receptor tyrosine kinases   SRC family    100922118 (LCK) Chromosome and associated proteins [BR:shr03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     100922118 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase SH3_16 Kdo SH3_3 Motif Other DBs NCBI-GeneID:  100922118 NCBI-ProteinID:  XP_003765473 Ensembl:  ENSSHAG00000008545 UniProt:  A0A7N4PWR2 LinkDB All DBs Position 3:546596892..546629280 Genome browser AA seq 509 aa AA seqDB search MGCSCSSSLEEDWMENIDVCERCHYPIVPLDAKSMFPMRNGSDIRDPLVTYEGLNPPVSP LQDNLVIALHSYKPSHDGDLGFEKGEQLKILEQNGEWWKAQSLTTGQEGYIPFNFVAKAN SLEPEPWFFKDLSRKDAERQLLAPGNTHGSFLIRESETTAGSFSLSVRDFDQSQGEVVKH YKIRNLDNGGFYISPRITFPNLQELVQHYSKVPDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGGGQFGEVWMGYYNGHTKVAVKSLKAGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSTGVKLTIHKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDSLNCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPEELYKLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgcagctgcagctccagcctcgaagaggattggatggaaaatattgacgtgtgt gaacgctgccattatcctattgtgcctttggatgccaagagcatgtttccaatgaggaat ggttctgacatccgggatcccttggtcacctatgagggtttaaacccacctgtgtctcca ttacaagataacctggtcatcgccctgcacagctataagccttcccatgatggggatttg ggctttgagaagggggagcagctgaagatcttggagcagaatggagaatggtggaaggca cagtccttgactactggccaagagggctatattcccttcaacttcgtggccaaagcaaac agcctggagcctgagccttggtttttcaaggacctgagccggaaggatgctgagagacaa cttttggcccctgggaacacccatggatccttcctcatcagagagagtgagaccactgca gggtccttctctctgtctgtgcgggattttgaccagagccagggggaagtggtgaaacat tacaagatccgcaacctggacaatggtggcttctacatttccccccgaatcacctttcct aatctgcaggaactggtccagcattactccaaagtcccagatgggctatgcactcgactg agccgaccctgccagacccaaaagccacagaagccctggtgggaagatgagtgggaggtt ccccgagagacgctgaagctggtggagaggctgggaggcggccagtttggggaggtctgg atggggtactacaatgggcacactaaggtggcagtgaaaagcctgaaagcgggcagcatg tccccggacgccttcctggcagaggccaacctgatgaaacagctgcagcaccagcggctg gtacgcctttatgcggtagtcacgcaggagcccatctacatcatcaccgaatacatggag aatgggagcctggtagacttcctcaaaacctcaacaggggtcaaactaaccatccataaa ttgctggatatggctgcacagattgctgagggcatggccttcattgaagagcggaactac atccaccgggaccttagggctgccaacatcctagtatcggactcactgaactgtaagatt gccgactttgggctagccaggctaattgaagacaatgaatacacagctagggagggagcg aaatttcccatcaagtggacagctcctgaggccatcaactatgggacatttaccatcaaa tcagatgtctggtcttttggaatcctgctgacagaaattgtcacctatggaaggatcccc tacccaggaatgaccaacccggaagtgattcagaacctggagcaaggctatcggatggta agacctgacaactgtccagaggagctgtacaaactgatgatgctgtgttggaaggagagg cctgaggatcggcccacttttgactacctgaggagtgtcttagaggacttcttcactgct acagagggccagtatcagccccagccatga

DBGET integrated database retrieval system