Sarcophilus harrisii (Tasmanian devil): 100922434 Help Entry 100922434         CDS       T02286                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr00230   Purine metabolism shr01100   Metabolic pathways shr01522   Endocrine resistance shr04015   Rap1 signaling pathway shr04020   Calcium signaling pathway shr04022   cGMP-PKG signaling pathway shr04024   cAMP signaling pathway shr04062   Chemokine signaling pathway shr04072   Phospholipase D signaling pathway shr04081   Hormone signaling shr04082   Neuroactive ligand signaling shr04114   Oocyte meiosis shr04211   Longevity regulating pathway shr04213   Longevity regulating pathway - multiple species shr04261   Adrenergic signaling in cardiomyocytes shr04270   Vascular smooth muscle contraction shr04371   Apelin signaling pathway shr04540   Gap junction shr04611   Platelet activation shr04713   Circadian entrainment shr04714   Thermogenesis shr04723   Retrograde endocannabinoid signaling shr04724   Glutamatergic synapse shr04725   Cholinergic synapse shr04727   GABAergic synapse shr04750   Inflammatory mediator regulation of TRP channels shr04911   Insulin secretion shr04912   GnRH signaling pathway shr04913   Ovarian steroidogenesis shr04914   Progesterone-mediated oocyte maturation shr04915   Estrogen signaling pathway shr04916   Melanogenesis shr04918   Thyroid hormone synthesis shr04921   Oxytocin signaling pathway shr04922   Glucagon signaling pathway shr04923   Regulation of lipolysis in adipocytes shr04925   Aldosterone synthesis and secretion shr04926   Relaxin signaling pathway shr04927   Cortisol synthesis and secretion shr04928   Parathyroid hormone synthesis, secretion and action shr04934   Cushing syndrome shr04935   Growth hormone synthesis, secretion and action shr04970   Salivary secretion shr04971   Gastric acid secretion shr04972   Pancreatic secretion shr04976   Bile secretion shr05032   Morphine addiction shr05163   Human cytomegalovirus infection shr05166   Human T-cell leukemia virus 1 infection shr05200   Pathways in cancer shr05207   Chemical carcinogenesis - receptor activation shr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:shr00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100922434 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100922434 (ADCY2)    04072 Phospholipase D signaling pathway     100922434 (ADCY2)    04024 cAMP signaling pathway     100922434 (ADCY2)    04022 cGMP-PKG signaling pathway     100922434 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100922434 (ADCY2)    04081 Hormone signaling     100922434 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100922434 (ADCY2)    04062 Chemokine signaling pathway     100922434 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     100922434 (ADCY2)    04922 Glucagon signaling pathway     100922434 (ADCY2)    04923 Regulation of lipolysis in adipocytes     100922434 (ADCY2)    04913 Ovarian steroidogenesis     100922434 (ADCY2)    04915 Estrogen signaling pathway     100922434 (ADCY2)    04921 Oxytocin signaling pathway     100922434 (ADCY2)    04926 Relaxin signaling pathway     100922434 (ADCY2)    04935 Growth hormone synthesis, secretion and action     100922434 (ADCY2)    04918 Thyroid hormone synthesis     100922434 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     100922434 (ADCY2)    04925 Aldosterone synthesis and secretion     100922434 (ADCY2)    04927 Cortisol synthesis and secretion     100922434 (ADCY2)   09154 Digestive system    04970 Salivary secretion     100922434 (ADCY2)    04971 Gastric acid secretion     100922434 (ADCY2)    04972 Pancreatic secretion     100922434 (ADCY2)    04976 Bile secretion     100922434 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     100922434 (ADCY2)    04727 GABAergic synapse     100922434 (ADCY2)    04725 Cholinergic synapse     100922434 (ADCY2)    04723 Retrograde endocannabinoid signaling     100922434 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100922434 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     100922434 (ADCY2)    04213 Longevity regulating pathway - multiple species     100922434 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     100922434 (ADCY2)    04714 Thermogenesis     100922434 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100922434 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     100922434 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100922434 (ADCY2)    05163 Human cytomegalovirus infection     100922434 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     100922434 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100922434 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100922434 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100922434 (ADCY2) Enzymes [BR:shr01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100922434 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  100922434 NCBI-ProteinID:  XP_031801973 Ensembl:  ENSSHAG00000002581 LinkDB All DBs Position 1:394595385..395200392 Genome browser AA seq 1102 aa AA seqDB search MWQEAMRRRRYLLDRAEAAAGGGGSGSGSGAGGCSGRLHKSRDWLYESYYCMSQQHPLIV FLLLIIMGACLALLSVFFALGLEAKEHVAFLITVPTALAIFFAIFILVCIESVFKKLLRV FSLVIWVCLVAMGYLFMCFEGSIFPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSS HTIVLSVCLSTLPGVKDHLIWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIK SRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQLENTNNFHNLYVKRHTN VSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLP ISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSH DVTLANHMEAGGVPGRVHITSVTLEHLNGAYKVEEGDGDIRDPYLKEHYVKTYFVINPKG ERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDV PMGQHHFQHRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKTL EKEYRATTLPAFKYYVTCACLIFFGIFIVQILVLPKTSVLGISFGAAFLVLSFILFICFA GQLLQCSKKASASLLWILKSSGIIANRPWPRITLTVTTTTIILTMAIFNMFFLNEAQMMI PSGSNMSNSSLSDSIDRKSQNTQKYFFLPYFIYSCILGLISCSVFLRINYELKMIIMLIA LVGYNIILLHTHAPILDEYSKLLMGRPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCR LDFLWKNKFNKEREEIETMENLNRVLLENVLPAHVAEHFLARNLKNEDLYHQSYDCVCVM FASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAAT GLSATPSQEHTQEPERQYMHIGTMVEFAFALAAKLDVINKHSFNDFKLRVGINHGPVIAG VIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETNIVLQTLGYMCTCRGIINVKGKG ELKTYFVHTEMARSLSQANVAS NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt atgtggcaagaagcgatgagaaggcgtcgctatctgctggacagggcagaggctgccgca ggcggaggtggcagcggctccgggtccggggctgggggttgtagcggccggctacacaag tcccgggactggctctacgagtcctattactgtatgagccaacagcacccactcatcgtc ttcctgttgctaattatcatgggcgcctgcctagccctcctctccgtcttctttgctttg gggctggaagctaaagagcatgtggcatttttaataacagttccaactgcccttgctatt ttcttcgcaatatttattctcgtctgcattgaatctgtatttaagaagctgcttcgtgtt ttctccttggtaatatgggtatgcctcgttgccatgggatatttattcatgtgttttgag ggatccatttttccttgggaccaggtatcattttttttattcattatctttgtggtatac actatgctgcccttcaacatgagagatgccataattgccagcgtactgacctcttcatcc cacaccatagttctgagtgtctgtctctctactcttccaggagtgaaggatcacctgatt tggcagatactagcaaatgttatcattttcatctgtggaaacctggcaggagcctaccac aagcatctcatggaactagctctacagcagacctatcaagatacttgtaattgcattaag tccaggatcaagttggaatttgaaaaacggcaacaggagcgtcttctgctctctttactg cctgctcacattgccatggaaatgaaagcagagatcattcagaggttgcagggacccaaa gcaggccagctggaaaacacaaacaactttcacaatctctatgtcaagcggcacaccaat gtgagcatattatatgctgacattgttggattcacccgtctggctagtgactgctctcca ggagaattggtacacatgctgaatgaactttttggaaagtttgatcaaattgccaaggaa aatgaatgcatgaggatcaaaattttaggagactgctactactgtgtgtctggccttcct atatctcttccaaaccatgccaagaactgtgtgaaaatgggactagatatgtgtgaagct ataaagaaagtaagagatgcaactggagttgatatcaatatgcgtgtgggagtacactct ggaaatgtcctctgcggtgtgattggtttgcagaagtggcagtatgatgtctggtctcat gatgttacactagcaaatcacatggaagctggaggtgttccagggcgtgttcacattact tcagttaccttagagcacttgaatggagcttacaaagtagaagaaggagatggagatata agggacccatatctgaaggaacattatgtcaaaacttattttgtgatcaatcccaaggga gaaagacgaagtcctcagcacctctttagaccaaggcatacattagatggagccaaaatg agagcatcagtccgcatgacccggtatttggagtcctggggagcagccaagccctttgca catttacatcacagggacagcatgacaacagaaaatggcaagatcagtaccacagatgtt ccaatgggtcagcatcactttcagcaccgcacattaagaaccaaatcacagaagaaaaga tttgaagaagaactgaatgaaagaatgattcaggcaattgatggaatcaatgctcaaaag caatggctcaaatctgaagacattcaaagaatttctctgcttttctataacaaaacatta gaaaaagaatacagagcaaccacattacctgcattcaagtattatgtgacttgtgcttgc ctcatcttctttggcatttttattgtgcagatattagtattaccaaaaacatctgttctt ggaatttcctttggagctgcatttcttgtgctttccttcatccttttcatctgttttgct ggacagcttctgcaatgtagcaaaaaagcctctgcctcattattgtggattttgaaatca tctggaataattgcaaatcgtccttggccacgaatcactctcacagttaccaccactact attatattaaccatggctatcttcaacatgtttttcctgaatgaagcacagatgatgatc ccttcaggttccaacatgtcaaattcaagtctttctgactcaattgaccgcaaatctcag aatacacaaaagtattttttcctgccttacttcatttacagctgcattctgggcttgata tcctgttctgttttcctgcgaataaactatgaattgaaaatgataatcatgctgattgca ctcgtgggttacaatatcatcctcttacatactcatgcccctatacttgacgaatacagt aagcttctaatgggcagaccaggcatctggaaagacctaaagaccatgggttctgtgtct ctctttatattcttcatcacattactggttctggggagacagaatgaatattactgtagg ttagacttcctatggaagaacaagttcaataaagagcgtgaggaaattgaaacgatggag aatctgaatcgtgtcctgctggaaaatgtgctccctgcccatgtggccgaacacttcttg gctagaaacttgaagaatgaggatttgtatcatcagtcctatgactgtgtctgtgtcatg tttgcttctattccggattttaaagaattttatacagaatcagatgtcaacaaagaaggc ttggaatgtcttcgactcctgaatgaaatcattgctgactttgatgatttgctgtccaaa ccaaaatttagtggagttgaaaagatcaagaccattggaagcacttacatggcagccaca ggactgagtgctacaccgagccaagaacacacacaggaacctgagcgccagtacatgcac attggcaccatggtggaattcgcttttgccctagcagctaaattggatgtaatcaacaaa cattccttcaatgacttcaagttgcgagtgggtattaaccatggccccgtaatagctggt gtaattggagctcagaaacctcaatatgacatttggggcaatacagtaaatgtggccagc agaatggacagcactggagtcttagataaaatacaggtcactgaggaaacaaacattgtc ttacagacattaggatacatgtgtacttgcagaggaataatcaacgtgaaaggaaaaggt gaactgaagacatatttcgtacatacagaaatggcaagatccctttcccaagcaaatgtg gcatcctga

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