Sarcophilus harrisii (Tasmanian devil): 100923926
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Entry
100923926 CDS
T02286
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8 isoform X1
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00230
Purine metabolism
shr01100
Metabolic pathways
shr01522
Endocrine resistance
shr04015
Rap1 signaling pathway
shr04020
Calcium signaling pathway
shr04022
cGMP-PKG signaling pathway
shr04024
cAMP signaling pathway
shr04062
Chemokine signaling pathway
shr04072
Phospholipase D signaling pathway
shr04081
Hormone signaling
shr04082
Neuroactive ligand signaling
shr04114
Oocyte meiosis
shr04211
Longevity regulating pathway
shr04213
Longevity regulating pathway - multiple species
shr04261
Adrenergic signaling in cardiomyocytes
shr04270
Vascular smooth muscle contraction
shr04371
Apelin signaling pathway
shr04540
Gap junction
shr04611
Platelet activation
shr04713
Circadian entrainment
shr04714
Thermogenesis
shr04720
Long-term potentiation
shr04723
Retrograde endocannabinoid signaling
shr04724
Glutamatergic synapse
shr04725
Cholinergic synapse
shr04727
GABAergic synapse
shr04742
Taste transduction
shr04750
Inflammatory mediator regulation of TRP channels
shr04911
Insulin secretion
shr04912
GnRH signaling pathway
shr04913
Ovarian steroidogenesis
shr04914
Progesterone-mediated oocyte maturation
shr04915
Estrogen signaling pathway
shr04916
Melanogenesis
shr04918
Thyroid hormone synthesis
shr04921
Oxytocin signaling pathway
shr04923
Regulation of lipolysis in adipocytes
shr04925
Aldosterone synthesis and secretion
shr04926
Relaxin signaling pathway
shr04927
Cortisol synthesis and secretion
shr04928
Parathyroid hormone synthesis, secretion and action
shr04934
Cushing syndrome
shr04935
Growth hormone synthesis, secretion and action
shr04970
Salivary secretion
shr04971
Gastric acid secretion
shr04972
Pancreatic secretion
shr04976
Bile secretion
shr05032
Morphine addiction
shr05163
Human cytomegalovirus infection
shr05166
Human T-cell leukemia virus 1 infection
shr05200
Pathways in cancer
shr05207
Chemical carcinogenesis - receptor activation
shr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100923926 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
100923926 (ADCY8)
04072 Phospholipase D signaling pathway
100923926 (ADCY8)
04024 cAMP signaling pathway
100923926 (ADCY8)
04022 cGMP-PKG signaling pathway
100923926 (ADCY8)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
100923926 (ADCY8)
04081 Hormone signaling
100923926 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100923926 (ADCY8)
04062 Chemokine signaling pathway
100923926 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
100923926 (ADCY8)
04923 Regulation of lipolysis in adipocytes
100923926 (ADCY8)
04913 Ovarian steroidogenesis
100923926 (ADCY8)
04915 Estrogen signaling pathway
100923926 (ADCY8)
04921 Oxytocin signaling pathway
100923926 (ADCY8)
04926 Relaxin signaling pathway
100923926 (ADCY8)
04935 Growth hormone synthesis, secretion and action
100923926 (ADCY8)
04918 Thyroid hormone synthesis
100923926 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
100923926 (ADCY8)
04925 Aldosterone synthesis and secretion
100923926 (ADCY8)
04927 Cortisol synthesis and secretion
100923926 (ADCY8)
09154 Digestive system
04970 Salivary secretion
100923926 (ADCY8)
04971 Gastric acid secretion
100923926 (ADCY8)
04972 Pancreatic secretion
100923926 (ADCY8)
04976 Bile secretion
100923926 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
100923926 (ADCY8)
04727 GABAergic synapse
100923926 (ADCY8)
04725 Cholinergic synapse
100923926 (ADCY8)
04720 Long-term potentiation
100923926 (ADCY8)
04723 Retrograde endocannabinoid signaling
100923926 (ADCY8)
09157 Sensory system
04742 Taste transduction
100923926 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
100923926 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
100923926 (ADCY8)
04213 Longevity regulating pathway - multiple species
100923926 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
100923926 (ADCY8)
04714 Thermogenesis
100923926 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100923926 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
100923926 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100923926 (ADCY8)
05163 Human cytomegalovirus infection
100923926 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
100923926 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
100923926 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100923926 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100923926 (ADCY8)
Enzymes [BR:
shr01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
100923926 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
100923926
NCBI-ProteinID:
XP_031803064
LinkDB
All DBs
Position
1:complement(619976662..620341546)
Genome browser
AA seq
1254 aa
AA seq
DB search
MELSDVRCLSSTEELYTINPTPPASGGSGGSGSGAGGGSRPQRLLWQTAVRHITEQRFIH
QSGVCGGNGKASDPGGPNHHAPHLQQAPALPLYPLGQPGRLGSAGKGGHNNGGGPTKVFP
ERRGSSSDLGFLHLDCAPSNSDFFLNWGYTYRGVIFPTLRNSFKSRDLERLYQLYFLGQR
RKSEVVMNILDVLTKLTLLVLHLTLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTS
YTYLQYSGLVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLV
TSLVQIILELIIPRLAVNSINQIVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVE
ARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHKIYIHRYENVSILFA
DVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDH
AHCCVEMGLSMIKTIRYVRSRTKHDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIAN
KLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLP
EDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQAL
HVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVC
AFIVLLFITAIQSLLPSSRMMPMVIQFSLLIMLHSALVLITTAEDYKCLPLMLRKTCCWI
NETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNQTSNSSAVFTDICSYPEYFVF
TGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYSLLMETIYASLFLHYDNFNHNGERDFLGT
KEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPS
HVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIAD
FDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALNESIQEI
NKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETY
LILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPLILPPRKLPGQYSLAAVVL
GLVQSLNRQRQKQILNENNNPGIIKGHYNRRTLLTASGPEPTAQAEGADKSDLP
NT seq
3765 nt
NT seq
+upstream
nt +downstream
nt
atggagttatccgatgttcgctgcttaagcagcacggaagaactctacaccattaacccg
acacccccggccagcggaggtagcggggggagcggtagcggagccggaggtggctcacga
ccccagaggctgctgtggcaaactgcggtgcgacacattacggaacagcgcttcatccac
cagagcggtgtctgcggcgggaacggaaaggctagcgaccctggcggccctaaccaccac
gcgccccacctccagcaagctccagccctccccctctaccctctgggccagccggggcgt
ctgggttcggccgggaagggcggtcataacaacgggggtggccccaccaaagtcttcccg
gagcggaggggcagcagcagtgacttgggcttcctgcacctcgactgcgctcccagcaac
tcggatttctttctcaattggggttatacctaccgaggggtgatcttccccaccctgcgg
aactcctttaagtcccgggacctggagcggctctaccagctctatttcctgggacagcgg
cgcaaatccgaggtggtcatgaacatcctggacgtgttgaccaaactgaccttgctcgtg
cttcacctgaccctagcatcggcccccatggaccccctcaaaggcatccttctgggcttc
tttacaggcatcgaggtggtcatctgtgctttggtggttgtcaggaaggacaccacttca
tacacgtacctacagtatagtgggctggtgacctgggtggccatgacgactcagatcctg
gccgccggactgggctacggactcctaggtgatgggattggctatgtgctcttcactctc
ttcgccacctacagcatgctgccgctgcccctcacctgggcgatccttgcggggttggtc
acatctctagtgcaaatcatcctggaacttatcatcccccgattggcagtgaattccatc
aaccagatagtggctcaggcggtcttgttcatgtgcatgaacacagcaggaatcttcatt
agctacctgtcagacagagcccaacgtcaagctttcctggaaacccgaagatgcgtggaa
gcaaggctgagactagaaacggagaatcagagacaggaacgactggtactttccgtattg
cctcggtttgttgtccttgagatgatcaatgacatgaccaatgtggaagatgagcattta
cagcaccagtttcacaagatctacatccatcgctatgaaaatgtcagtattctttttgca
gatgttaaaggatttaccaacctttccacgaccttgtcagcacaggagctggtcaggatg
ttgaacgaactctttgccagatttgatcgactagcccatgagcatcattgtcttcggatt
aagatcttgggggactgctactattgtgtttctggactccctgaacctcgtcaggaccat
gcccactgctgtgttgaaatggggctcagtatgatcaagaccatcaggtatgttaggtca
aggacaaagcatgacattgacatgcgcataggcatccattctggatcagtgctctgtgga
gtgttgggtctccggaagtggcagtttgatgtttggtcctgggacgtggacatcgcgaat
aaactagaatcaggtggaatccctgggaggattcacatctccaaagcaacactggactgc
ctcaatggtgattataatgttgaagagggacatggtaaagaaagaaatgaattcttgagg
aaacataacatagagacctatttaataaaacagccagaggaaagtcttctgactttgcct
gaagacattgtaaaggagtcggtcagctcctcagataggagaaacagtggggccacattt
acagaaggatcctggagccctgaactcccatttgataacattgtgggaaaacagaatact
ctggctgccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttg
catgtccagtctgggcctgaggaaattaacaagagaatagagcacaccatcgacttacgg
agtggcgataaattgagaagagagcatatcaagcctttctcactgatgtttaaagactcc
agcctggagcataagtattctcaaatgagggatgaagtattcaaatcaaacttggtctgt
gcatttatcgtgcttctctttatcaccgcaatccaaagtttgcttccttcttcaaggatg
atgccaatggtcattcagttttctctcctgatcatgctgcactcagctcttgttcttatc
accacagcggaggattataagtgcttaccacttatgctgcgaaaaacttgctgttggatt
aatgagacctacctggccagaaatgttatcatctttgcctccatcttgattaatttcctt
ggtgccatcctaaatattctgtggtgtgattttgacaagtcaatacccttgaagaaccag
acttccaattcgtcggctgtatttacagatatctgctcatacccagagtatttcgtcttc
acgggtgtgttggccatggtgacctgtgcagttttcctgagacttaattctgtcttgaaa
ctggctgtgttgctgattatgattgcaatctattctctactgatggagaccatttatgct
tccctgtttctgcactatgacaactttaatcacaatggagaaagagatttcctgggaacc
aaggaggcctctctgcttttgatggcaatgtttctccttgctgtgttttaccatggacag
cagctggaatatacagctcgcctggacttcctctggcgtgtccaggccaaagaggagatc
aatgagatgaaagaactgagggagcacaatgagaacatgcttcgcaacattctgccaagt
cacgttgctcgacatttcttagaaaaggaccgagataatgaagaattgtattcccaatcc
tatgatgctgttggtgtgatgtttgcttctatccccggatttgctgatttttattctcag
acagaaatgaataaccaaggagtggaatgtctgcgcttgctgaatgaaatcattgctgac
tttgatgagttacttggtgaagaccgatttcaagatattgaaaaaattaagacaattggc
agcacttacatggccgtatcaggcttgtcaccagagaaacagcaatgtgaagataagtgg
ggacacttatgtgctctggctgacttctctctcgccctgaacgaaagcatacaggagatc
aacaagcattcatttaacaattttgagctccgcattggtatcagccacggatctgtggta
gcaggagtgattggcgccaagaagccgcagtatgatatctggggtaaaactgtcaacctg
gcaagtcgtatggacagcacgggtgtcagtggtcggatccaggtgcccgaggagacatat
ctcatcctcaaagaccaaggctttgcttttgactacagaggagagatttacgtcaagggc
atcagtgaacaggaaggaaaaatcaaaacgtattttcttctgggaagagtccaacccaat
ccactaatcttaccaccaagaaaactgcctggacagtactccttagcagctgtagtccta
ggactggttcaatcactgaacaggcaaagacagaagcaaatactcaatgagaacaacaac
cctggcattataaagggacattataaccggcggactttgttgactgccagtggacctgaa
cccacagcccaagcagaaggcgctgataaatctgacttgccataa
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