Sarcophilus harrisii (Tasmanian devil): 100924829 Help Entry 100924829         CDS       T02286                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr04022   cGMP-PKG signaling pathway shr04068   FoxO signaling pathway shr04081   Hormone signaling shr04140   Autophagy - animal shr04152   AMPK signaling pathway shr04211   Longevity regulating pathway shr04213   Longevity regulating pathway - multiple species shr04910   Insulin signaling pathway shr04920   Adipocytokine signaling pathway shr04923   Regulation of lipolysis in adipocytes shr04930   Type II diabetes mellitus shr04931   Insulin resistance shr04932   Non-alcoholic fatty liver disease shr04935   Growth hormone synthesis, secretion and action shr05010   Alzheimer disease shr05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100924829 (IRS2)    04022 cGMP-PKG signaling pathway     100924829 (IRS2)    04152 AMPK signaling pathway     100924829 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     100924829 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100924829 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100924829 (IRS2)    04923 Regulation of lipolysis in adipocytes     100924829 (IRS2)    04920 Adipocytokine signaling pathway     100924829 (IRS2)    04935 Growth hormone synthesis, secretion and action     100924829 (IRS2)   09149 Aging    04211 Longevity regulating pathway     100924829 (IRS2)    04213 Longevity regulating pathway - multiple species     100924829 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100924829 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100924829 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100924829 (IRS2)    04932 Non-alcoholic fatty liver disease     100924829 (IRS2)    04931 Insulin resistance     100924829 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Mcp5_PH Motif Other DBs NCBI-GeneID:  100924829 NCBI-ProteinID:  XP_031814563 UniProt:  A0A7N4PE17 LinkDB All DBs Position 3:complement(161196396..161236264) Genome browser AA seq 1390 aa AA seqDB search MASPPLNGLLTPANSSNGGGGGGGGGSGGGSTNLNNNNNNNNHSVRKCGYLRKQKHGHKR FFVLRGPGSGSEEQGGGGSGGQPPLPARLEYYENEKKWKNKSGAPKRVIALDSCLNINKR ADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLLNEGKAAYDSNSLYPHCLSSGA SSASASSCSASLPGSGGSGSFGAAAEDLHYGLITPATAAYREVWQVNLKPKGLGQSKNLT GVYRLCLSARTIGFVKLNCEVPSVTLQLMNIRRCGHSDSFFFIEVGRSASTGPGELWMQA DDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSSTHPISVPGTRRHHHHLVNLPP SQTGLLRRSRTDSLAATPPASGAPIGTQAPGAGKCSSCRVRTASEGDGSSGGGGVSCRPV SVAGSPMSPGPVRTPLSRSHTLSSSCSASMRPSKMMLAPAGGPLQHSRSMSMPVSHSPPS ATSPGSLSSSSGHGSASYSLPQGQHPHPHQIHHHQGQRPSSGSASASGSPSDPGFMSLDE YGSSPGDLRAFCSNRSNTPESIAETPPARDGSGTELYGYMTMERPLSLGGRTYRRVSGEG ATDLDKGHRKRTYSLTTPARQRAVPQVSSASLDEYTLMRASFTGSSSRLYPASSPKVTYN PYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGVAPMTGGSIGSCKSDDYMPMSPTSVSA PKQILQPRMAVASLAAGAASQAASSATCGRGSPLNGSSYKTSSPAESSPEDSGYMRMWCG SKLSVESSEGKLLPNGDYLNMSPSDAGASLTPPDFFYDSVPLPGGGEPPKGVPGCCYSSL PRSYKTPCPRNGDSDQYVFMNSPVGRRIVEEEQEQPRLQPLPTTATPCTESTRPFVSNGG SHSQPHHLVPSTVRQSGSSSGNNNRPENFLIQRCRAVRPTRLSLEGLRTLPSMHEYPLPP EPKSPGEYINIDFSESGAHLSPPPPPLLTSAASSSSLLSASSPASSMGSGTPGTSGDSRR RSPLSDYMNLGFGSPKSPKSGTEGGGSVGSLDALMSPEASSPCPPLPTPPASSSTSSSQQ QQQLPPPPPPGELYRLPPASSTCHPAPVSASSSSCPPETGDSGDYTEMAFGIAATPPQPI AAPPKPESARVTSPTSGVKRLSLMEQVSGVEAFLLASPPPDPHRGAKVIRADPQGGRRRH SSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGPNGSGGESLGGGEEEPSTS PHLRQPSLPLPPQPQQPRWAQNQPGALVGCPGSSGSPMCRETSAGFQNGLNYIAIDVRDE AGLLLQQQQQSGDKSTWTRTRGLSGLISGGNGSNAGGCVGPGSGPLPTANTYASIDFMSH HLKEATAVKE NT seq 4173 nt NT seq  +upstreamnt  +downstreamnt atggccagcccgccactaaacgggctcctgaccccggcgaattcctccaacggaggaggc ggcggcggcggcggcggcagtggaggcggcagcaccaacctcaacaacaacaacaacaac aacaaccacagcgtgaggaagtgcggctacctgaggaagcaaaaacatgggcataaacgc tttttcgtactgcggggccccgggagcggcagtgaagagcagggcggtggggggtccgga ggacagccacccctgcccgcgaggctggagtactacgagaatgagaaaaagtggaagaac aagtcaggggccccgaaaagggtgatcgccttagactcctgcctcaacatcaacaagcgg gcagacgccaagcacaagtatctgatcgccctctacaccaaggacgagtacttcgctgtg gccgccgaaaatgagcaggagcaggagggctggtaccgggcgctcacggacctgctcaat gagggcaaagctgcctacgactcgaactcgctctaccctcactgcctctcgtccggcgcc tcgtcggccagcgcctcatcctgcagcgcctccctgccgggttcgggcggcagcggctcc tttggggcagcggctgaggatctccattacgggctgatcaccccggccaccgctgcttac cgggaggtctggcaggtaaacttgaaacccaaagggctgggacagagcaaaaacctgaca ggggtgtaccggctctgcctttccgcgcgcaccatcggttttgtgaagctcaactgcgag gtgccgtcggtcactctgcagctgatgaacatccgacgctgcggccactcagacagcttc ttcttcatcgaggtagggcgctctgcgtccacgggtcctggcgagctctggatgcaggcg gatgactctgtggtggcccagaacatccatgaaaccatcctggaggccatgaaagccctg aaggagctgttcgaattccgtccccgcagtaagagccagtcctccggctcctcttccacc caccctatcagcgtcccaggcacccggcgtcaccaccaccatctggtcaacctgcccccc agccagaccgggctccttcgccgatcccggaccgacagtctggccgccacgcctcctgcc tccggtgctcccattgggactcaggccccaggagctgggaaatgtagctcttgtcgggta cgcacagccagcgagggggatggcagcagcgggggcggaggggtgagttgcaggcccgtt tcagtggccggcagccccatgagtcccggcccggtgaggactcccctaagcaggtctcat actctgagcagcagctgcagcgcctccatgcgacctagtaagatgatgttagcccctgca gggggccccctgcagcacagcagatccatgtctatgcccgtatcccattcccctccgtct gccaccagccctggcagcctctcgtccagcagcgggcatggctcagcttcttactccttg cctcaaggacagcatccacatccacaccaaattcatcaccaccagggccagcggccctct agtggcagtgcttctgcttctggctcccccagtgacccaggcttcatgtccttggacgaa tatggctctagccctggggacctccgggctttctgcagcaaccgaagcaacactcccgag tccatagctgagacccccccagcaagagatggcagtgggactgaactatatggatacatg accatggagaggcccctaagtttaggtggccgaacctaccgaagggtatctggggagggg gccacagacttggacaaaggtcacagaaagaggacttactctctgaccacacctgctcgc caacgggcagtgccccaagtgtcctctgcctcccttgatgaatatactctgatgcgggca agctttacaggcagctcaagccgcctttacccagcctcatctcccaaagtgacctataac ccatacccagaggactatggggacattgagattggctcccatcggagctccagcagtaat cttggagcagatgatggctacatgcccatgactcctggagtggctccaatgacagggggc agcattggaagctgcaaaagcgatgactatatgcccatgagtcccaccagtgtctctgct cccaaacaaatactgcaaccacggatggcagtagcctcccttgctgcaggtgcggcatcc caggcagcctcatcagcaacatgtggtagaggctctccactgaatggcagtagttacaag accagttctccagctgaaagctctccggaggacagtgggtacatgcggatgtggtgtggt tccaagctctcagtggaaagctctgagggcaagctacttcccaatggggattaccttaac atgtcccctagtgatgctggagcttctcttacaccacctgacttcttctatgactcagtc ccattgcctggtggtggagagccacccaaaggagtcccaggctgctgttacagttcactg ccccgttcctacaaaacaccctgtcctcgaaatggggatagtgaccaatatgtattcatg aattctccagtggggaggaggattgtggaagaggagcaagagcaaccaagactacagcca ctgcccaccacagctacaccctgcactgagtccaccaggccctttgtgtctaatgggggc agccattcccaacctcaccacctagtgccttcaacagttaggcagagtggcagcagcagt ggcaacaacaacaggccagagaatttcctcattcagcgttgcagagcagtccggccaacc cgtctgtccctggaggggcttagaaccctacctagcatgcatgagtacccattgccacct gagcctaaaagcccaggtgaatacatcaacattgactttagtgaatctggagcccacctt tcaccacctccacctcctttgctgacttcagcagcctcatcatcatcactgctctcagct agcagccctgcctcttcaatgggttcaggtacccctggcactagtggtgacagccggagg cgctctcctctctctgactatatgaaccttggctttggctcacccaagtcacccaaatct ggcactgagggtggtggctctgtaggctccttggatgccttgatgtctcctgaggcctcc tccccctgcccaccactgccaacaccgcctgcctcctcctctacttcctcctcacagcag caacagcaattaccacctccaccaccaccaggagagctgtaccgcctgcctccagcttct tctacctgccacccagcccctgtttctgcctcctcctcctcatgtccccctgagacaggg gatagtggtgactacaccgagatggccttcggcatagctgccactccaccacaacccatt gcagcacctccgaagccagaaagtgcccgggtgaccagccctacatctggtgtgaaacga ctgagtttgatggagcaggtgtctggtgtagaggcctttctgttggccagcccaccccca gacccacaccggggtgccaaggttatccgtgctgacccacagggtggccgccgacgccac agctcggaaaccttctcctcgaccactactgtgactcctgtatccccttccttcgcacac aatcctaagcgccacaactcggcctctgtggaaaatgtctctctcaggaaaagtagcgaa ggacccaatggcagtggtggtgagagtcttggaggaggtgaagaagagccatctacatct cctcatcttcggcagccatcgcttcctttgccacctcagccccagcagccaaggtgggca caaaaccaacctggagcattagttggttgccctggaagcagtggatctcctatgtgtcgg gagacatcagccggcttccagaatggtctcaactacattgccattgatgttagagatgaa gctggtctattgttacagcagcagcaacagtctggagacaagagtacctggacccggacc cgtggcctcagtgggctcatcagtggtggaaatggcagcaatgcaggtggttgtgtggga ccaggctctggaccactgcctacagccaacacctatgctagcattgactttatgtcccat cacctgaaggaggctacagctgtgaaagagtga

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