Sarcophilus harrisii (Tasmanian devil): 100927200
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Entry
100927200 CDS
T02286
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04010
MAPK signaling pathway
shr04020
Calcium signaling pathway
shr04151
PI3K-Akt signaling pathway
shr05200
Pathways in cancer
shr05216
Thyroid cancer
shr05223
Non-small cell lung cancer
shr05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100927200 (RET)
04020 Calcium signaling pathway
100927200 (RET)
04151 PI3K-Akt signaling pathway
100927200 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100927200 (RET)
05230 Central carbon metabolism in cancer
100927200 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
100927200 (RET)
05223 Non-small cell lung cancer
100927200 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100927200 (RET)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100927200 (RET)
Protein kinases [BR:
shr01001
]
Receptor tyrosine kinases (RTK)
RET family
100927200 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD3
Pkinase
RET_CLD4
RET_CRD
Cadherin
RIO1
Haspin_kinase
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
100927200
NCBI-ProteinID:
XP_031812239
UniProt:
G3WA34
LinkDB
All DBs
Position
2:complement(604675862..604835829)
Genome browser
AA seq
1105 aa
AA seq
DB search
MSLRGGLVGLLLLCEAVLGLYFSRDTYSEKLYIDEPVGTPLLYVHALQDARGEVPHFRLG
QHLYSTYRSQPHKNDWFQINEDTGLLYLNQSLDQRALEKLSARNGGFPLLTIYLQVFLSP
KPLRESDCHWPSCAKVMLSVINTTMPACSSLKPREFCFLETGLSFRIRENKPPGTFHQFR
LLPVQHLCPNISISYQLLGEEALPFYSDKDTMEVNMRHSLDREEKEKYELIAKCTVWEGL
REEVVMVPFPVTVYDEDDSPPNFPNGINTANAVVEYKRKEGTVLAVLQVFDADVVPSSVD
IPRKYIHTMLTSDPLVNEFFRVEHSPNETSYNSNGSRVRAMMHDYKLVLNRSLPITESHS
FQLGVLVNDTDYQGPGGVLHLYFNVTILPVSIRFPNISYSFSVNRNAHRYAQIGKVCIEN
CKEFHGVNITYKLQSLSVNCTALGIITTPESTTGNLFVNDTSMLQRPECTGMKYLVIASD
RQSKKQSRTTSTISVEGNFFPEEEGCPISCAVNKRRSECEECGGLGTLMGTCQWRQGDGK
GISKNYSTCTPSLKTCPDGNCDAVESRDLHICPQDCIRGDIIGGHERGEWRGIKAGYGVC
NCFPEKKKCFCEPDDDKEPLCDEVCRMVIAVAVLFSFIFSVLLSSYFIRRYHKNSHKPPI
ASAEMTFRRPAQAYPISYSSSNVRRPSLDSMENQVSVDAFKIPEDPKWEFPRKNLVLGKT
LGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELKDLLSEFNLLKQVNHPHVIK
LYGACSQDGPLYLIVEYAKYGSLRSFLRESRKVGPSYMGGNGNRNSSYLDNPDERALTMG
DLISFAWQISRGMHYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYEEDSYVKRS
KGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGYR
MERPENCSEEMYNLMLHCWKQEPDKRPTFGEISKDLEKMMVKSRDYLDLAASTPSDSLLY
DDGLSEEETPLVDCNNAPLPRTLPSTWIENKLYGMSYPNWPEESPVPLTRFDGTNSVFSR
YANDSVYANWMVSPSAAKLMDKFNS
NT seq
3318 nt
NT seq
+upstream
nt +downstream
nt
atgtctcttcgcggggggctcgtggggcttctccttctttgtgaagctgtgttgggtctt
tatttttctcgggacacttactcagaaaaactatacattgacgaacctgttggaacaccc
ctgctctatgttcatgccttacaagatgccagaggggaggtgccacacttccgcctgggc
cagcatctctatagtacctatcggtctcagccgcacaagaatgactggttccagatcaat
gaagatacaggccttctctacctcaaccaaagtctggaccaaagggccttggagaaactg
agtgcccgaaatggaggatttcccctactcaccatctaccttcaagtattcctctcacca
aagccattacgggagagtgattgccattggcccagctgtgccaaagtgatgctgtctgtc
atcaataccaccatgccagcctgcagttctctgaagcctagggaattctgctttttggag
acagggctctcatttcgcatcagggagaataagccaccgggtactttccaccaattccgt
ttacttcctgtgcagcatctgtgtccaaatatcagcatttcctaccaattgcttggagaa
gaagcccttcccttctattctgataaggacaccatggaggtgaacatgaggcactcactg
gaccgggaagaaaaggagaagtatgaattgattgccaagtgcacagtttgggaaggtttg
cgagaagaggttgtgatggtgccctttcctgtgactgtatatgatgaagatgattcacct
cctaatttccccaatggcatcaacacagctaatgcagttgtggagtacaaacggaaagag
ggtacagtattggctgtcctgcaggttttcgatgcagatgtcgtgccttcctctgtggac
atcccaagaaagtacatacataccatgctgaccagtgaccctttggtcaatgagttcttc
cgggtggaacactcaccaaatgaaacttcatacaactctaatggaagtcgtgtgcgggcg
atgatgcatgattacaaactggtgctcaaccgaagccttcctatcacagagagccattct
ttccagctgggagtcctggtgaatgacactgactaccagggtcctggaggagtactccat
ctctatttcaatgtgaccatcctgcctgtcagcatacggtttccaaacatctcctattcc
ttctcagtaaatcggaatgctcaccgatatgcacagattggaaaagtttgcattgaaaac
tgcaaggagttccatggagtaaatattacctacaaactacagtcactcagtgttaattgc
accgctctgggcatcatcaccaccccagaaagcacaacagggaatctgtttgtgaatgac
acctctatgctgcagagaccggaatgcacaggaatgaaatatttggtaattgcatcagac
agacagagcaagaaacaatccagaacaacatctactatctcagtagaaggaaattttttc
cctgaggaggagggctgtcccatttcatgtgcagtgaacaagagacgttcagaatgtgaa
gaatgtggtggcttgggcaccctgatgggcacatgccagtggagacaaggagatggcaaa
ggaatttccaagaactattcgacttgcactccaagcctcaagacttgtcctgatggcaac
tgtgatgcagtagaaagtcgagatcttcatatctgccctcaagattgcatacggggagac
attattggtggtcatgagagaggagaatggaggggaatcaaggctggatatggagtctgc
aactgctttccagaaaaaaagaagtgtttctgtgagccggatgatgataaagaaccgctt
tgtgatgaagtctgcagaatggtcattgccgtagccgtacttttctccttcatcttctct
gtgctgctctcttcctacttcatccgtcgctaccacaagaactcccacaagccacccatt
gcctctgcagagatgaccttcaggaggcctgctcaggcttaccccatcagctattcttcc
tccaatgttcgccggccatctttggattccatggagaaccaggtctcagtggatgccttc
aaaatccctgaggatccaaagtgggaatttcctcggaagaatttagttcttggaaaaacc
ctaggagaaggagagtttggaaaggtcgtcaaggcaacagctttccgactcaaagggaaa
gcaggctacaccactgtggcagtgaaaatgctgaaagaaaatgcttctccaagtgagctc
aaagacctgctgtcagagtttaacctgctaaaacaggtcaaccacccccacgtcattaaa
ctctatggcgcctgcagtcaggatggacctctctacttgattgtggagtatgctaagtat
ggttctctgcggagcttcctccgggaaagccggaaggtgggacccagctacatgggaggt
aatggcaatcggaattctagctacttggacaatccggatgagagggcactgaccatggga
gatctcatttccttcgcctggcagatttcccgaggaatgcattatcttgcagaaatgaag
ctggtccaccgtgatttagcagctaggaatgtcttggtggctgaaggacgcaaaatgaag
atttctgattttggcctttcccgagatgtttatgaagaggactcctatgtcaaaaggagc
aagggccggattcctgtaaagtggatggcaattgagtctctttttgatcatatctacact
acccaaagtgatgtgtggtcatttggtgtgttgctctgggaaattgtaaccctaggagga
aatccctatcctggtattcctcctgaacgtctcttcaaccttctaaaaacgggctatcga
atggagaggcctgaaaactgcagtgaagaaatgtacaatctgatgttgcactgctggaag
caggaaccagataagaggccaacatttggggagatcagcaaagacctagagaagatgatg
gtgaagagtagggactacttggatcttgcagcttctaccccatctgactccttactttat
gatgatggcctttcagaagaggagactcccctcgtggactgtaataatgctcccctccct
cgaaccctcccttccacatggattgaaaacaaactctatggcatgtcatacccgaactgg
cctgaggagagtcctgtcccactcacaagattcgatggcactaactctgtgttttcaaga
tatgcaaatgatagtgtatatgctaactggatggtttcaccctcagcggcaaaattaatg
gacaagtttaatagttaa
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