Sarcophilus harrisii (Tasmanian devil): 100929204 Help Entry 100929204         CDS       T02286                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr04010   MAPK signaling pathway shr04014   Ras signaling pathway shr04015   Rap1 signaling pathway shr04022   cGMP-PKG signaling pathway shr04066   HIF-1 signaling pathway shr04068   FoxO signaling pathway shr04072   Phospholipase D signaling pathway shr04150   mTOR signaling pathway shr04151   PI3K-Akt signaling pathway shr04152   AMPK signaling pathway shr04211   Longevity regulating pathway shr04213   Longevity regulating pathway - multiple species shr04520   Adherens junction shr04910   Insulin signaling pathway shr04913   Ovarian steroidogenesis shr04923   Regulation of lipolysis in adipocytes shr04930   Type II diabetes mellitus shr04931   Insulin resistance shr04932   Non-alcoholic fatty liver disease shr04960   Aldosterone-regulated sodium reabsorption shr05010   Alzheimer disease shr05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100929204 (INSR)    04014 Ras signaling pathway     100929204 (INSR)    04015 Rap1 signaling pathway     100929204 (INSR)    04066 HIF-1 signaling pathway     100929204 (INSR)    04068 FoxO signaling pathway     100929204 (INSR)    04072 Phospholipase D signaling pathway     100929204 (INSR)    04022 cGMP-PKG signaling pathway     100929204 (INSR)    04151 PI3K-Akt signaling pathway     100929204 (INSR)    04152 AMPK signaling pathway     100929204 (INSR)    04150 mTOR signaling pathway     100929204 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     100929204 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100929204 (INSR)    04923 Regulation of lipolysis in adipocytes     100929204 (INSR)    04913 Ovarian steroidogenesis     100929204 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100929204 (INSR)   09149 Aging    04211 Longevity regulating pathway     100929204 (INSR)    04213 Longevity regulating pathway - multiple species     100929204 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100929204 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100929204 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100929204 (INSR)    04932 Non-alcoholic fatty liver disease     100929204 (INSR)    04931 Insulin resistance     100929204 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:shr01001]     100929204 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:shr04090]     100929204 (INSR) Enzymes [BR:shr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      100929204 (INSR) Protein kinases [BR:shr01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    100929204 (INSR) CD molecules [BR:shr04090]  Proteins   100929204 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like B2 Motif Other DBs NCBI-GeneID:  100929204 NCBI-ProteinID:  XP_031811798 LinkDB All DBs Position 1:673365490..673511373 Genome browser AA seq 1375 aa AA seqDB search MGAVRPLTVGLPPLLLLLLSASCGLISGEVCPSMDIRNNLTQLNMLEHCSVIEGNLQILL MFKTKPEDFRDLSFPKLTMITEYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFE MVHLKEIGLHSLMNITRGAVRIEKNNELCYLSTIDWSQILDSVEDNYIVDNKDDKEECGD VCPGAVKGVNSCKSTVINGQFIERCWTHNHCQKVCPPSCKWQGCTASGQCCHSECLGNCS EPNDPEKCVACRNFYLDGKCVETCPPNYYHFQDWRCVNFSVCQELHNKCKNSRKPSCPQY VIHNNKCIPECPSGYTMNSTNLHCTPCSGPCPKVCNIEADRTIDSVHAAQALRGCTVING SLVINIRGGNNIAVELEANLGLIEEITGYLKIRRSYALVSLSFFRKLHLIRGESLEIGNY SFYALDNQNLRQLWDWSKHNLTIAKGKLFFHYNPKLCLSEIHRMEEVSGTKGRQEKNDIA LKTNGDQASCENERLKFSSIRTTHDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEF DGQDACGSNSWTVVDVEPPVRSNDPKTQNQHPGWLMRNLKPWTQYAIFVKTLVTFSDERR TYGAKSEIIYVQTNATVPSVPLDPISVSNSSSQIILKWKPPSEPNGNITHYLVHWERQAE DIELYELDYCHKGLKLPSRTWSPPFESEDSQKHNQSNHEDPNGECCSCPKTDSQILKELE ESSFRKMFENYLHNEVFIPRKASSGNGADDSRPARRRRDLRVRVANMTVVTPTESSFSNT SSTTAPASTEEPKPFEKVKSKESLVISGLQHFTGYRIELQACNHDEQESRCSLAAYVSAR TMPEAKADDIVGAVIHEVLENNLVHLRWQEPKHPNGLIILYEVNYWRVGDTEELHLCVSR KRYANEQGCKFRVLQPGNYTVRIRATSLAGNGSWTEHTYFYVADYLDVPSNIAKIVIGPV IIIIFLISVVVVLYVVVKKRQTEGPTGPLFASSNPEYLSASDVYVPDEWEVAREKISLLR ELGQGSFGMVYEGNAKDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFSCHHVV RLLGVVSKGQPTLVVMELMVHGDLKSYLRSLRPDAENNPGRPPPSLREIIQMAVEIADGM AYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPES LKDGVFTTYSDVWSFGVVLWEISSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVNS LMQMCWQYNPKMRPTFLEIIEMLKDDLHPSFREVSFFYSEENKPPENEEFEMDFENMESI PLDPSSYSQRDEVLGRDNGPSLGLKGNYEERIPYTHMNGGKKNGRILSLPRSNPS NT seq 4128 nt NT seq  +upstreamnt  +downstreamnt atgggggccgtgaggccgctgactgtcgggctgcccccgttactgctgctgctgctgagc gcttcgtgtggcttgatctctggagaagtgtgcccaagtatggacattcggaataacctc acacagttgaacatgttggagcactgttctgtgattgaaggcaacttacagatactgctt atgtttaagacaaagcctgaagatttccgggacctcagtttccccaaacttaccatgatc acagagtacttactactctttcgagtgtatggacttgagagcctcaaggaccttttccct aacttgacggtcattcgtggatcccgcctatttttcaactatgctctggtcatcttcgag atggtccacctcaaggagattggcctccacagcctgatgaacatcacccgtggggctgtg cgcatcgagaagaataatgagctgtgttacttgtcaaccatcgattggtctcagattcta gactcagtggaagacaactacattgtggataacaaagatgacaaagaagaatgtggggat gtctgcccaggcgcagtgaagggagtcaacagctgcaaatctacggtgatcaatggccag tttattgagcggtgctggacccacaaccattgtcagaaagtgtgtccaccctcatgtaag tggcagggctgcacagcaagtggacagtgttgccacagtgaatgtctagggaactgctcg gagcccaatgaccctgagaagtgtgtggcctgccgaaacttctatctggatggcaagtgt gtggagacttgccctccaaactattatcacttccaggactggagatgtgtgaactttagc gtctgccaggagctccacaacaagtgcaaaaactcccggaagccatcgtgcccccagtat gtcatccacaacaacaagtgtatccccgaatgtccctctggctataccatgaactccacc aacctgcattgtactccctgctcgggtccctgtccaaaggtctgtaacatcgaggctgac cggaccatcgactcagtgcatgctgctcaggccctgcgaggatgcaccgtcatcaatggg agcctagtcataaacatccgtggtggcaacaacatagcagttgaactagaagccaatttg ggtttgattgaagagatcacggggtaccttaagatccgacgttcctatgccttagtatcc ctctccttcttccggaagctgcacctcattcggggagagtctctggaaatcgggaactac tccttctatgccctggacaatcagaacttaagacagctatgggactggagcaaacataac ctcaccatcgccaaagggaagctcttcttccactataaccccaaactctgcctgtctgaa atccacagaatggaagaagtttctggcacaaagggccggcaggagaagaatgatattgcg ttgaagaccaacggtgaccaagcttcttgtgaaaacgagcggctcaagttttcttccatt agaacaactcatgacaagatcttattgaggtgggagccttattggcctcctgatttccga gacctcttgggattcatgctgttctacaaagaagcgccttaccagaatgtgactgagttc gatggccaggatgcctgcgggtccaatagctggacagtggttgatgttgagcccccagtg agatcgaatgatcccaagacacagaatcaacacccagggtggttgatgcgaaacctgaag ccatggacccagtacgccatatttgtgaagaccctagtcactttctctgatgaacggaga acatatggtgccaaaagtgaaatcatttatgtccagactaatgccactgttccttcagtc ccattagacccaatatccgtttccaattcttcatcccagatcattttaaaatggaaacca ccctctgagccaaatggtaatattacgcactacttagtgcactgggagaggcaagctgaa gacatcgagctctatgaacttgattactgccataaggggttaaagctgccttccaggacc tggtctcctccgtttgagtctgaagattcccaaaaacacaatcagagcaaccacgaggac cccaatggcgagtgttgctcttgcccaaagactgactcccagatcttgaaggaactggaa gaatcttcctttcgaaagatgtttgaaaattatctccacaacgaggttttcatccccaga aaagcatcctcagggaatggcgctgacgactctaggccggcaaggaggcgaagggatctc cgggttcgcgtggcaaacatgactgtggtgacacccacggagtcctccttctcgaacacc tcttccacaacggcgccggccagcacggaggagcccaagcccttcgagaaggtgaaatct aaggagtccctggtcatttctggccttcagcattttactggctacaggatcgagctccag gcatgcaaccatgacgaacaagagtccaggtgtagccttgccgcgtatgtcagcgcgaga accatgcctgaagccaaggctgatgatattgtcggtgcagtgatccatgaggttcttgag aacaacttagtccatctgcggtggcaggagcccaaacatcccaatggtcttattattctc tatgaagtcaattactggcgcgttggagacactgaggaactgcatctctgtgtttcccgc aaacgttatgccaatgaacagggctgcaaattccgagttctccagccaggcaactacacc gttcgcatccgagctacctctttggcaggaaatggttcgtggactgaacatacctacttc tacgttgcagattatttagatgtcccgtcgaatattgcaaaaattgtcatcggcccagtc atcattatcattttcttgatcagcgtggttgtagttctttatgtcgtcgtgaagaagagg caaacggaaggaccgacgggcccactgttcgcctcttccaatccagaatacctcagtgcc agtgatgtttatgtaccagacgagtgggaagtcgctcgagagaaaatcagcctcctccgt gagcttggccaaggctcttttggcatggtgtatgagggcaatgccaaggatattgtcaaa ggggaggctgagacccgcgtggccgtgaagaccgtgaatgagtctgccagcctccgggaa cgtattgagttcctgaacgaggcctccgtcatgaagggcttcagctgccatcatgtggtc cgcctcctgggggtggtctccaaagggcagcccaccctggtggtcatggagctgatggtg cacggggacctgaagagttaccttcgctctctgaggccggatgcagagaacaatcctggt cgtcctccccccagtctccgggagatcatacagatggctgtggagatcgccgacggcatg gcctatttgaatgccaagaaatttgttcacagggatctcgctgcccgaaactgtatggtt gccgaagactttactgtaaagataggagactttggaatgaccagagacatctatgagaca gattattatcgaaaagggggcaagggtttgctcccagtgaggtggatggcgccagaatct ttaaaagatggtgtctttactacctattcggacgtttggtcctttggtgtggtcctgtgg gagatcagcagcctagctgaacagccttaccaaggcctatccaatgagcaggtcctgaag tttgtaatggatggagggtacctggaccaacctgataattgtccagagagagtgaacagc ctaatgcagatgtgctggcagtacaaccccaagatgcgccccaccttccttgagatcatt gagatgctgaaggatgaccttcatcccagcttccgggaggtctcctttttttacagtgag gaaaacaagcctcctgagaacgaggagtttgagatggactttgaaaacatggagagcatc cccctggacccttcttcttactcgcagagggacgaggtcctggggagggacaatgggccg tcgctgggccttaaggggaactatgaggagcggataccttatacccacatgaatgggggc aagaagaacggacgcatcctctccttgccacggtcgaacccttcctaa

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