Sarcophilus harrisii (Tasmanian devil): 100930062
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Entry
100930062 CDS
T02286
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04014
Ras signaling pathway
shr04072
Phospholipase D signaling pathway
shr04148
Efferocytosis
shr04360
Axon guidance
shr04625
C-type lectin receptor signaling pathway
shr04630
JAK-STAT signaling pathway
shr04650
Natural killer cell mediated cytotoxicity
shr04660
T cell receptor signaling pathway
shr04670
Leukocyte transendothelial migration
shr04722
Neurotrophin signaling pathway
shr04920
Adipocytokine signaling pathway
shr04931
Insulin resistance
shr05168
Herpes simplex virus 1 infection
shr05205
Proteoglycans in cancer
shr05208
Chemical carcinogenesis - reactive oxygen species
shr05211
Renal cell carcinoma
shr05220
Chronic myeloid leukemia
shr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100930062 (PTPN11)
04630 JAK-STAT signaling pathway
100930062 (PTPN11)
04072 Phospholipase D signaling pathway
100930062 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100930062 (PTPN11)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100930062 (PTPN11)
04660 T cell receptor signaling pathway
100930062 (PTPN11)
04670 Leukocyte transendothelial migration
100930062 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
100930062 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
100930062 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100930062 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
100930062 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100930062 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100930062 (PTPN11)
05211 Renal cell carcinoma
100930062 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100930062 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
shr01009
]
100930062 (PTPN11)
Enzymes [BR:
shr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
100930062 (PTPN11)
Protein phosphatases and associated proteins [BR:
shr01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
100930062 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
100930062
NCBI-ProteinID:
XP_031804478
Ensembl:
ENSSHAG00000006173
LinkDB
All DBs
Position
1:689866505..689932531
Genome browser
AA seq
603 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQDLKYD
VGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRPENKNKNRYKNILPFDHTRVVLHDGDPNEL
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGAMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPTDPGGVLDFLEEVHHKQESIPDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPTCPEYDYSSPPPKGQERCKDFHVKNEFGR
FAF
NT seq
1812 nt
NT seq
+upstream
nt +downstream
nt
atgacatcccggagatggtttcacccaaatatcactggagtggaggcagaaaatttactg
ctgacacgaggtgttgatggcagcttcttggccaggcccagtaagagtaatccaggagac
ttcacactttctgttaggcggaatggcgctgtcacacacatcaagattcagaacactggc
gactattacgacctatatgggggggagaagtttgccaccctggctgagttagtacagtat
tatatggagcatcatggacaattgaaagaaaagaacggagacgttattgagctgaaatac
ccactgaactgtgcagatcctacctcggaaaggtggtttcatgggcacctctctgggaaa
gaagcagagaagttactgactgaaaaaggaaaacatggaagcttcctggtgcgggaaagc
cagagccacccgggggactttgttctctctgtgcgcacgggggatgataaaggcgagagt
aacgatggcaaatcgaaagtgacgcatgtcatgattcgctgtcaggatctgaaatatgat
gtcggtggaggagagaagtttgattctttaactgaccttgtggagcattacaagaagaac
cccatggtggaaactctgggtactgtgctacagctaaagcagcccctgaatacaactcgc
attaatgctgcagagattgaaagccgtgtgagagaattaagcaaattagctgagaccacg
gataaagttaaacaaggtttttgggaagaatttgagactctacaacagcaggaatgcaag
ctcctatatagtcgtaaagaaggtcagcggccagaaaataaaaacaaaaacagatataaa
aacattttgccatttgatcataccagggttgtcctacatgacggggatccgaacgaacta
gtttcagattatattaatgcaaacatcatcatgcctgaatttgagaccaagtgtaacaat
tcaaagcccaaaaaaagttatattgcaacgcaaggctgtctgcagaatacagtgaatgac
ttctggagaatggtgtttcaggagaattcgcgagttattgtcatgacgacgaaagaagta
gagagaggcaagagtaaatgtgtcaagtactggcccgatgaatatgctctaaaggagtac
ggggctatgcgagttaggaatgttaaagaaagcgctgctcatgattatacgctaagagag
cttaagctctctaaggttggacaagctctacttcaggggaatacggagagaacagtgtgg
cagtatcattttagaacctggcccgatcatggcgtgcccactgaccctgggggtgttctg
gactttttagaagaggtccatcacaagcaggagagcattcctgatgcaggccctgtggtg
gtgcattgcagtgctggaattggcaggacaggaactttcattgtgattgacatccttatt
gacattatcagagagaaaggtgtggattgtgacattgatgttcccaagaccattcagatg
gtgagatcccagagatcagggatggtccaaacagaagcccagtacagatttatctacatg
gctgtgcagcattacattgagacgctacaacgcagaattgaggaggagcagaaaagcaag
agaaaagggcatgaatatacaaacattaaatattctctagcagaccagacaagtggagat
cagagtcctctcccaccttgcaccccgactccaacctgtccagaatatgactattcctcc
ccacccccaaaaggtcaagaaagatgcaaggactttcatgtgaaaaatgaatttggaagg
tttgcattctga
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