Sarcophilus harrisii (Tasmanian devil): 100931354 Help Entry 100931354         CDS       T02286                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K07187   insulin receptor substrate 2 Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr04022   cGMP-PKG signaling pathway shr04068   FoxO signaling pathway shr04081   Hormone signaling shr04140   Autophagy - animal shr04152   AMPK signaling pathway shr04211   Longevity regulating pathway shr04213   Longevity regulating pathway - multiple species shr04910   Insulin signaling pathway shr04920   Adipocytokine signaling pathway shr04923   Regulation of lipolysis in adipocytes shr04930   Type II diabetes mellitus shr04931   Insulin resistance shr04932   Non-alcoholic fatty liver disease shr04935   Growth hormone synthesis, secretion and action shr05010   Alzheimer disease shr05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100931354 (IRS4)    04022 cGMP-PKG signaling pathway     100931354 (IRS4)    04152 AMPK signaling pathway     100931354 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     100931354 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100931354 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100931354 (IRS4)    04923 Regulation of lipolysis in adipocytes     100931354 (IRS4)    04920 Adipocytokine signaling pathway     100931354 (IRS4)    04935 Growth hormone synthesis, secretion and action     100931354 (IRS4)   09149 Aging    04211 Longevity regulating pathway     100931354 (IRS4)    04213 Longevity regulating pathway - multiple species     100931354 (IRS4)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100931354 (IRS4)   09164 Neurodegenerative disease    05010 Alzheimer disease     100931354 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100931354 (IRS4)    04932 Non-alcoholic fatty liver disease     100931354 (IRS4)    04931 Insulin resistance     100931354 (IRS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  100931354 NCBI-ProteinID:  XP_031800907 LinkDB All DBs Position X:18822008..18858737 Genome browser AA seq 1220 aa AA seqDB search MASYSAAGERGVRRWRPERETEAKKQTSAPVPGGSGSGSESGSGSSSSSSTSSSSTSTNT SSSNSSSSSSGSTSSGSSGSGSGSGSGSGSGSGSGSGSSFFSGSGGSAGGGDIGSSGSRS KGRGIGGMWRGAEDGARCCSPDRGDPGLRQLLQAAGADVRKCGYLRKQKHGHKRYFVLRT ASRLAPARLEYYESEKKFRSSLRAAAAAAAAAASAGPSAGAPPAVQPKRVIPLYQCFTVS RRADAKHRHIVALYTKDDYFAMVAESEQEQESWYQALSLLMGQSKTRSSGTGTEEGEDGT AGGGDGVATDEGGAAGGGAAAGAAAGAGAAAGAAAGEEDDDEDGAFKEVWQVQVKPKGLG QSKNLSGIYRLCLSSKEVHLVRLNAEVPSVKLQLLCIRRCGHSEHFFFLEVGRSSSIGPG EIWMQVEDSVVAQHMHETFLETMKALKAFTDFRPRSKSQSSCTNPISFLSTRRHLGYLQP CLGMSRRSRTDSMASTPPSCKGGTYRFRTSSEGEGTMDRPFKTVTGSLMQLNPGRMNVAR PEGGRYVRAALHACCHARSASLPVSPFPSGTSPAPDGVARPSSSVCGTPGDGSVVSDDHG PSPGDVRYFRLRSNTPDSVGHTPPIREEHCSNEYMSMNKQRASRSAGGEHMEAEKFFKKK TFSLPKPAAVTMQQKTTQTTPFDEDCAGNPRLLFSSEPPRGRETPKAELGENGSNRNRGR KRAEDDGYMPMMPGVAAPLKSNSDYLPMAPRSASAPKPGASWSSSQKDSRGYMMMFPRAV PPAPGRGSRGRFASKGAANQDDEDNEYMDMSPQNPLPPRQSQEASSAHPPSFSKSLSSLF SLPKSFRSLGEHHNHDSDYVPMASPGRLLSTVSESAPRVNQEAPPPKSSSKAPAAKASDG GFLHRRAARPTKLPLGSRGSSVPRIYERALERDSPGEYINIDFSRKAGHAPYSFSAGCSP SAFGPCGDHAHSPFADYVSFAVDNNPLNTAKEMVNSLTLSDSKPPRSQPSAGGARSPLGA AARASTPTNADDDYTEMTFNPAAATTVPLAPQSDGPVKMDSPSSAVNRLRIADTSPEGST SSLPDISPEPPVVPKAVRADPQGRRRHSSETFSQEGAGAASSSLFADSRWQNSASFDSIW SKSGEGASNSEETKMSRITSAGFQNGLNYIALNLRDAKSGAGPAAPNSRQRNGAPAGDSG AYVSIFSKGDIFQCASAKKD NT seq 3663 nt NT seq  +upstreamnt  +downstreamnt atggcgagttactccgccgctggggagcgaggggtacggaggtggcggccggagcgggag actgaggctaagaagcagacatcagccccagtgcccggtggcagtggcagtggcagtgag agcgggagcggcagcagcagcagcagcagcaccagcagcagcagcaccagcaccaacacc agcagtagcaatagcagtagcagcagcagcggcagtaccagctccggctcctccggctcc ggctcgggctccggctcgggttccggctccggctcgggctccggctccggctccagcttt ttttcaggcagcggcggcagcgccggcggcggggacataggcagcagcggcagcagaagc aaaggcagaggcatcggcggcatgtggaggggcgcagaggacggcgcccgctgctgctcc ccggatcgcggggacccgggcctgagacagctgctgcaggcggccggagccgatgtccgc aaatgcgggtacctgcggaagcagaagcatggccacaaacgctacttcgtgctgcggacg gccagtcgcctggccccggcgcgcctcgagtactacgagagcgagaagaagttccgcagc agccttcgcgccgcggcggcggcggccgccgccgccgcttcggccggcccctcggcgggc gcgccccccgccgtgcagcccaagcgcgttatcccgctgtaccagtgcttcacggtgagc cgccgagccgatgccaagcaccgccacatcgtcgccctttacaccaaggacgactacttc gccatggtggccgagagcgagcaggagcaggagagctggtaccaagcgctgagtctcctg atgggccagagcaagacgcgcagctccggcaccgggaccgaggaaggcgaagacggcacc gccggcggcggcgacggcgtggccaccgacgaggggggtgcggccggcggcggtgcggcc gccggtgccgccgcgggtgccggtgcggccgccggtgccgccgcgggtgaggaagacgac gacgaggacggagccttcaaggaggtgtggcaggtgcaggtgaaacccaaggggctgggc cagagcaagaacctgagcggcatctatcgcctttgcctgtccagcaaagaggtgcatctg gtgcgcctgaacgccgaggtgcccagcgtgaagctgcagctgctctgcattcgccgatgc ggccactcggagcacttcttctttctcgaggtgggcaggtcgtcatccatcggccccggg gagatctggatgcaggtggaggactcggtggtggctcagcatatgcacgagaccttcctg gaaaccatgaaagccctcaaggccttcaccgacttcaggccccggagcaagagccagtcg tcgtgcaccaaccccatctcgttcctctccaccaggaggcacctgggctacctgcagccc tgcctggggatgtcccgcaggtcccgcaccgacagcatggccagcaccccgccttcctgc aagggcggcacctaccgattccggacctccagcgagggcgaaggcaccatggacagaccc ttcaaaacggtcacgggaagcctgatgcagctgaaccctgggcggatgaacgtggcccgg cccgaaggcggcaggtacgttcgagccgctctccacgcctgctgtcacgctcgctctgcc tccctgcccgtgtctccctttccctcggggaccagcccagccccggacggcgtggccagg ccttcgagctccgtgtgcgggacccctggcgacggaagcgtcgtctccgatgaccacggc cccagccccggagacgtgaggtatttccgactgaggagcaacaccccggattccgtgggg cacaccccacccatccgagaggagcactgttccaacgagtacatgtccatgaataagcag cgcgccagtaggagcgccggcggtgagcatatggaggctgaaaagttcttcaagaagaaa actttttccctgcctaagccagcggctgtaaccatgcaacagaaaacaacccagacgact cccttcgatgaggactgcgccggaaacccccggctgctcttttcctccgagcccccgcgg ggcagagagacccccaaagcggagcttggggagaacgggtccaatcggaaccgcggcaga aaaagagccgaggacgacggctacatgcccatgatgccgggggtcgccgcgcccctcaaa agcaacagcgattacttgcccatggctccgcggagtgcttccgccccgaagcccggcgct tcttggtcatcctctcagaaggactcccgaggctacatgatgatgttccccagggccgtc ccgcccgccccgggccgcggttcccgaggcagattcgcttccaagggagccgctaatcag gacgacgaggacaacgagtacatggatatgtccccgcagaatcctctcccgcccaggcag tctcaggaggcgagttctgctcaccctccctccttctccaaaagtctcagctccctcttc tctctgccgaaaagtttccgaagtctcggcgaacaccacaaccacgacagcgattatgtc ccgatggcgtcgcccgggagactcttaagcaccgtgtccgaaagcgccccgagggttaac caggaagccccgccgcccaagagctcgtctaaagcgccagccgccaaagcttcggacggg ggcttcctgcaccgcagggccgcgagacccaccaaactccctctgggctccaggggaagc agcgtgcccaggatctacgagcgggccctggaaagggacagccccggggagtacatcaac atcgacttcagccgaaaagcgggccatgccccgtattccttctccgccggatgctccccg tctgcgttcggcccctgcggggaccacgcgcactcccccttcgccgattacgtgagcttc gccgtcgataacaacccgctcaacaccgccaaggagatggtcaattccctgaccctgtcc gactccaagccccctcgcagccagccgagcgcgggcggcgcccgaagccccctcggcgcc gccgcccgcgccagcaccccgaccaacgcggacgacgactacaccgaaatgactttcaac cccgccgccgcgacaaccgtgcctttagccccccagagcgacggtccggtcaagatggac agcccctcttcggccgtaaatcgccttcgcatcgccgacacgtctcccgagggcagcacc tcctccctccccgacatcagcccggaaccaccagttgtacccaaggcggtccgagccgac ccacagggcagaaggcgccacagctccgaaactttctcccaggaaggagccggagccgcc tcgtcctctctcttcgccgatagcagatggcagaattccgcctcctttgacagcatctgg tccaaatccggtgaaggtgcttcgaactccgaggagaccaagatgtccagaatcacctcg gctggctttcagaacggcctcaactacatcgccctgaatttacgtgatgctaaaagtggg gccggcccagctgctccgaattctcgccagaggaacggggctcctgccggggacagcggc gcctatgtcagcatcttctccaaaggtgacatcttccagtgtgcttctgcgaaaaaagac tga

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