Sarcophilus harrisii (Tasmanian devil): 100931580 Help Entry 100931580         CDS       T02286                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr01524   Platinum drug resistance shr04115   p53 signaling pathway shr04210   Apoptosis shr04215   Apoptosis - multiple species shr04217   Necroptosis shr04620   Toll-like receptor signaling pathway shr04621   NOD-like receptor signaling pathway shr04622   RIG-I-like receptor signaling pathway shr04623   Cytosolic DNA-sensing pathway shr04625   C-type lectin receptor signaling pathway shr04657   IL-17 signaling pathway shr04668   TNF signaling pathway shr04932   Non-alcoholic fatty liver disease shr04936   Alcoholic liver disease shr05010   Alzheimer disease shr05016   Huntington disease shr05022   Pathways of neurodegeneration - multiple diseases shr05132   Salmonella infection shr05134   Legionellosis shr05142   Chagas disease shr05145   Toxoplasmosis shr05152   Tuberculosis shr05160   Hepatitis C shr05161   Hepatitis B shr05162   Measles shr05163   Human cytomegalovirus infection shr05164   Influenza A shr05165   Human papillomavirus infection shr05167   Kaposi sarcoma-associated herpesvirus infection shr05168   Herpes simplex virus 1 infection shr05169   Epstein-Barr virus infection shr05170   Human immunodeficiency virus 1 infection shr05200   Pathways in cancer shr05203   Viral carcinogenesis shr05416   Viral myocarditis shr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     100931580 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100931580 (CASP8)    04215 Apoptosis - multiple species     100931580 (CASP8)    04217 Necroptosis     100931580 (CASP8)    04115 p53 signaling pathway     100931580 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100931580 (CASP8)    04621 NOD-like receptor signaling pathway     100931580 (CASP8)    04622 RIG-I-like receptor signaling pathway     100931580 (CASP8)    04623 Cytosolic DNA-sensing pathway     100931580 (CASP8)    04625 C-type lectin receptor signaling pathway     100931580 (CASP8)    04657 IL-17 signaling pathway     100931580 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100931580 (CASP8)    05203 Viral carcinogenesis     100931580 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100931580 (CASP8)    05161 Hepatitis B     100931580 (CASP8)    05160 Hepatitis C     100931580 (CASP8)    05164 Influenza A     100931580 (CASP8)    05162 Measles     100931580 (CASP8)    05168 Herpes simplex virus 1 infection     100931580 (CASP8)    05163 Human cytomegalovirus infection     100931580 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     100931580 (CASP8)    05169 Epstein-Barr virus infection     100931580 (CASP8)    05165 Human papillomavirus infection     100931580 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     100931580 (CASP8)    05134 Legionellosis     100931580 (CASP8)    05152 Tuberculosis     100931580 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100931580 (CASP8)    05142 Chagas disease     100931580 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     100931580 (CASP8)    05016 Huntington disease     100931580 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     100931580 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100931580 (CASP8)    05416 Viral myocarditis     100931580 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100931580 (CASP8)    04932 Non-alcoholic fatty liver disease     100931580 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100931580 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:shr01002]     100931580 (CASP8) Enzymes [BR:shr01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      100931580 (CASP8) Peptidases and inhibitors [BR:shr01002]  Cysteine peptidases   Family C14: caspase family    100931580 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED GH3_C PYRIN HTH_50 PGC7_Stella CCDC92 Motif Other DBs NCBI-GeneID:  100931580 NCBI-ProteinID:  XP_031814206 UniProt:  G3VCE6 LinkDB All DBs Position 3:complement(82633726..82679902) Genome browser AA seq 470 aa AA seqDB search MDFREILCKISEEIDREELTALKFLCLDHIPMRKQELINDTLKFFEILEEKVLLKKNNLF FLKELLYYICRIDLLTNLNTNITELEHQIRTKAQVSSYRVLLFNLSQEVAKFELKSFKFI LRNKIPKCKLEDNMTLIDIFIEMEKRGILGEENLGTLKEVCDVIDKTLVKKIEDYESSRV ERSIERVPVEIQYVEEMMTEQATTGDFPGEKVQDKAYKMNSRPRGYCLIINNNDFQRARE EKPEYKKLNDRKGTDVDAEALKNTFKELHFEIVTLQDRTAKQIHQDLQIFQNKNHKERDC FVCCILSHGDKGTIYGTDGQEVAIRDLTSYFSSSNCVSLAGKPKVFFIQACQGRTMQGGL TLYTDSEQERESLEVDTLLQNECIPDEADFLLGMATVENYLSYRHVTDGTWYIQSLCKNL KEGCPRGLDILDILTKVNAEVSQKIDSKNKGKQMPQPKYTLRKKLSFPIN NT seq 1413 nt NT seq  +upstreamnt  +downstreamnt atggatttccgtgaaattctgtgcaagatttcagaagaaatagatagagaagagctgact gctctgaaattcctttgcttggatcacatcccgatgaggaagcaggaacttatcaatgat actttgaaattctttgagatacttgaagaaaaggttttgttgaagaagaacaatctgttc ttcttgaaggaactgctgtattacatatgccgaatagatctcctcacaaatttgaacact aacataacagagttagagcatcaaattcgaaccaaagcccaggtttcctcctatagggtt ctgctttttaatctgtcacaagaagtggcaaaatttgaattgaaatccttcaaatttata ttaaggaacaaaatccccaagtgcaaactagaagataatatgaccttaattgatattttc attgagatggaaaaacgaggaattttaggagaagaaaacctgggtaccctgaaggaagtt tgtgatgtcattgataagactctggtgaagaaaatagaagactatgaatcaagcagagtg gaaagaagcatagagagagttccagtggaaatccaatatgttgaagaaatgatgactgag caggcaacaactggagattttccaggagaaaaggtccaggacaaagcatataaaatgaac agcaggcctcgggggtactgcttgatcatcaacaataacgacttccaaagggcaagggaa gaaaaacctgagtacaagaaactaaatgataggaaagggactgacgtagatgcagaagct ctaaaaaataccttcaaagagcttcattttgaaattgtgactttacaagatcgcacagca aaacaaatacaccaagacctacagatcttccagaacaagaaccacaaagagagagattgc tttgtttgctgcatcctgtcccatggagataaaggcaccatctatggcactgatgggcag gaggtagccatcagagatctgacatcatatttctctagttccaattgtgtctcccttgct ggtaaacccaaagtattcttcattcaagcttgtcaaggcagaacaatgcagggtgggctc accctctacacagattctgagcaggaaagagaatctttggaagtggatacattgcttcag aatgaatgcattccagatgaggctgactttctgctggggatggcaaccgtggagaattat ctctcttatcgacatgtaacagacggaacctggtatatacagtccctttgcaagaatctg aaggaaggatgtcctcgaggactggatattctcgacatcctgacaaaagtaaatgctgaa gtgagccaaaaaattgactctaagaacaaagggaaacaaatgccacaacctaaatatact cttaggaaaaaactttcctttcccattaactag

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