Sarcophilus harrisii (Tasmanian devil): 100932425
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Entry
100932425 CDS
T02286
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00061
Fatty acid biosynthesis
shr00620
Pyruvate metabolism
shr00640
Propanoate metabolism
shr01100
Metabolic pathways
shr04152
AMPK signaling pathway
shr04910
Insulin signaling pathway
shr04920
Adipocytokine signaling pathway
shr04922
Glucagon signaling pathway
shr04931
Insulin resistance
shr04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100932425 (ACACB)
00640 Propanoate metabolism
100932425 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100932425 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100932425 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100932425 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100932425 (ACACB)
04922 Glucagon signaling pathway
100932425 (ACACB)
04920 Adipocytokine signaling pathway
100932425 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100932425 (ACACB)
04931 Insulin resistance
100932425 (ACACB)
Enzymes [BR:
shr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100932425 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100932425 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100932425 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
ATPgrasp_Ter
Motif
Other DBs
NCBI-GeneID:
100932425
NCBI-ProteinID:
XP_031804617
Ensembl:
ENSSHAG00000010467
LinkDB
All DBs
Position
1:700449681..700567491
Genome browser
AA seq
2446 aa
AA seq
DB search
MVPLVLLFSYLIFLWLVWSIMADAKSVTKSKSETKTQRQAPFSTCVSKGEPVHQNVDNQS
PAASLQLDTPACLEGPADGPKRLTSRPPPHTKTCPPLDVTESCAKPQANGLEGQGSPGSP
SSPPGSQGKRLQSSSKEDQKRAQIKKQLMTNFILGSFDDNSSDDETPDGLFRASSRKSSR
SSFGSLSFDSASLRSMTESEMSVPTMRPSMSGLHLVKRGREQKKLDLHRDFTVASPAEFV
TRFGGNYVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYI
KMADHYVPVPGGPNNNNYANVELIVDISKRLPVQAVWAGWGHASENPKLPELLQKHGIAF
LGPPSGAMWALGDKVASTIVAQTLQIPTLPWSGSGLVVDWQEEDLQQMKRISVPPEMYNR
GCVKDVEEGLQAAEKIGFPVMIKASEGGGGKGIRKAESAEDFPNLFRQVQSEIPGSPIFV
MKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAMPMVFEHMEQCA
VRLAKTVGYVSAGTVEYLYSEDGHFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGV
PLNRLKDIRILYGESPWGVTPISFENPINPPIPRGHVIAARITSENPDEGFKPSSGTVQE
LNFRSSKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAVSNMVVALKELSIRGDFR
TTVEYLVNLLETESFQSNDIDTGWLDHLIAERVQAEKPDIMLGVVCGALNVADALFRTCM
TDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSLTMFVLIMNNCHIEIDAHR
LNDGGLLLSYDGNSYTTYMKEEIDSYRITIGNKTCVFEKENDPTILRSPSAGKLVQYLVE
DGGHLTTGTTYAEMEVMKMIMTLSVQEDGRIYYVKRPGAVLQAGCMIARLELDDPSKVHA
AEPYTGDLPCQQTLPIMGEKLHQVFHNVLENLTNVMNGYCLPEPIFSTKLKEWVNKLMVT
LRSPSLPLLELQEIMTSVSGRIPPSVEKAVRKVMAQYASNITSVLCQFPSQQIANILDSH
AATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRKYLQVEHHFQQAHYDK
CVINLREQFKPDMSPVLNCIFSHAQVAKKNQLVTMLIDELCGPDPSLTDELLSILGELTQ
LSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSET
TIFDVLPNFFYHANQVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSH
PNRMSLPVSINNPDLLRHSTELFMDSGFSPLCQRMGAMVAFHRFEDFVRNFDEVISCFAN
LAKESPLFSEARSMLYSEDCKCLKDEPIHILNVAIQYADHLEDEELVPIFRTFVQSKKLV
LVEYGLRRITFLIAQEREFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFELKA
VPCANHKMHLYLGAARVKEGTEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEA
MDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEV
KINIRMTPTGTAIPIRLFLTNESGYYLDISLYKEVTDPRSGNIMFHSFGNKQGAQHGMLI
NTPYVTKDLLQAKRFQAQSLGTTYIYDFPEMFKQALYKLWGSSEKQPKDILTCTELVLDS
QGQLVEMNRLPGGNEVGMVAFKMLLKTREYPNGRYIIVIGNDITFRIGSFGQEEDLLFLR
VSQLARAEGIPKIYLSANSGARIGLAEEIRHMFHVAWVDPEDPCKGFKYLYLTPQDYTKI
SSLNSVHCMHVEEEGESRYVITDIIGKDDGLGVENLRGSGTIAGESSLAYEEIITISMVT
CRAIGIGAYLVRLGQRVIQVDNSHIILTGASALNKVLGREVYTSNNQLGGVQIMHFNGIS
HITVPDDFEGVYTILEWLSYMPKDTHSPVPIITPIDPIDREIEFTPSKAPYDPRWMLAGR
SHPTVKGSWQSGFFDQNSFKEIMEPWAQTVVTGRARLGGIPVGVIAVETRTVEMVVPADP
ANLDSEAKIIQQAGQVWFPDSAFKTAQAIKDFNREKLPLMIFANWRGFSGGMKDMYDQVL
KFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDPTINPLCMEMYADKESRGGVLEPE
GTVEIKFRKKDLIKTMRRIDSIYMKLVEQLGAEDLPEKDRKDLESKLRAREEHLLPVYHQ
VAVQFADLHDTPGRMQEKGVISDILEWKTSRTFLYWRLRRLLLEDIVKNKILQANGELSH
VHIQSMLRRWFMETEGAVKGYLWDNNQVVVEWLEKHLQQEDGLHSAIRENIKCLKRDSVL
KTIRGLVQDNPEVAVDCVIHMTQHISPADRAQIAHLLATMESPAST
NT seq
7341 nt
NT seq
+upstream
nt +downstream
nt
atggtcccgctggtcctgctgttctcgtacctgatttttttatggttagtttggagcatc
atggcggatgccaagtctgttaccaagagtaagtctgaaaccaaaacccagcgccaggcg
cctttttcaacttgtgtcagcaaaggggagccagtccaccaaaatgtagacaatcagtca
cccgcagccagcctgcaactcgacacgccagcgtgcctcgaaggccccgccgatggcccg
aagcgactgacatctcgcccgccaccgcacacgaaaacatgcccaccgttagatgtgacc
gagagctgcgcgaagcctcaggccaatggcctggaggggcaagggagtccagggtctcca
tcctcccctccgggctctcagggaaagcgcctccaatcttcttcgaaggaagaccagaaa
cgggcccagatcaaaaagcagctgatgaccaatttcatcctgggctcctttgatgacaac
tcttccgatgacgaaacccctgatggattgttcagagcttcctccaggaagagcagccgg
tcaagttttggctctttgtcttttgactcggcttcccttcggtccatgactgagtccgaa
atgtctgtaccaaccatgaggcctagcatgtcaggactgcacctggtaaaaagaggaaga
gaacagaagaaattggaccttcatcgggacttcacagtcgcctctccggctgagtttgta
actcgctttggggggaattacgttattgaaaaggttctcattgccaataatggcattgct
gctgtcaagtgtatgcgatccattcgaagatgggcctatgagatgtttcgaaatgagagg
gccatccgcttcgtggtcatggtcacgccagaagacctcaaagccaacgcagagtacatc
aagatggcagatcattatgtccctgttccgggagggccaaacaataataattatgccaac
gtagagctcatagtggatatctccaagcgactcccagtgcaggctgtgtgggctggctgg
ggccatgcctcggaaaaccctaaactgccagaactgctccagaagcatggcattgctttc
ttaggcccacccagtggagccatgtgggcactgggagataaggttgcttcgaccatagtt
gcccagaccctgcagattcctacgctaccctggagcgggagtggtcttgttgtggattgg
caggaagaggatctccagcaaatgaagagaatcagtgtccctccagaaatgtataacaga
ggctgcgtgaaggacgtagaagaaggtttgcaggctgcagaaaaaattggcttcccggtg
atgatcaaagcttctgaagggggtggaggcaaagggatccggaaagctgagagtgctgag
gacttcccgaacctcttcagacaggtgcagagtgagatcccgggctcaccaatttttgtc
atgaagctggctcagcacgcccggcacctggaagtccagatccttgcagatcagtatggg
aatgctgtgtcgctctttgggagagactgctccatacagcggagacaccaaaagattata
gaggaggcgccggctaccatcgccatgcccatggtgtttgagcacatggaacagtgtgcc
gtgcgcttggccaagacggtgggctatgtgagcgcggggaccgtagaatacctctatagc
gaagatggccacttccatttcttggaactgaacccccgtttgcaggtggaacatccctgc
acagagatgatcgccgatgtcaacttgccggctgctcagttgcagattgccatgggagtg
cctctgaacaggctgaaggacattcggatcctgtatggagagtcgccatggggcgtcacg
cccatttcctttgaaaaccccatcaatccacctattcccagaggccacgtgatcgccgcc
aggatcaccagcgaaaatccagatgagggttttaagccaagttctgggaccgtccaggag
ctgaatttccgcagtagcaagaacgtatggggctacttcagcgtggcggccgctgggggc
ctgcatgagtttgccgactcccagtttggtcactgcttctcctggggagagaaccgagaa
gaagctgtctcgaacatggtggtggccctgaaggagctgtcgatccgaggagatttcagg
accacagtggagtatctcgttaacctgctggagacagagagcttccagagcaatgacatc
gacacgggctggctggatcacctcattgctgagagggtacaggctgagaaacctgacatc
atgcttggggtggtctgtggagccttgaacgttgcagacgccttgttcaggacctgcatg
actgacttccttcattcattggaaaggggccaggttcttccagcagactctctgctgaac
atcgtggatgtggagctgatctatggaggggtgaagtatatccttaaggttgcccgacaa
tccctgaccatgtttgttctcatcatgaacaactgtcacatcgaaatagatgcccacagg
ctcaatgatggcgggctgctgctgtcctatgatggtaatagctacaccacgtacatgaag
gaagaaatcgacagttaccggatcaccattggcaataagacatgtgtgtttgagaaggag
aatgatcccaccatcctgagatctccctctgcgggaaaactggtacagtacttagtggag
gatggaggccatctgaccaccggaaccacctatgcagaaatggaggtaatgaagatgatc
atgaccttgagtgtgcaggaagatggacggatctactacgtgaagcggccaggagctgtg
ctccaagcaggctgtatgatagccaggctggagctggacgatccttctaaagtccacgca
gctgaaccatacacaggggacctgccctgccagcaaactctgcccatcatgggagagaag
ctgcaccaggttttccacaatgtcctggagaacctgaccaacgtcatgaatggctactgt
ttgccagaacccattttcagcaccaagctcaaggagtgggttaacaagctgatggtcacc
ctgcggtccccctccctaccccttctggagctccaggagatcatgaccagcgtctctggc
cggatcccgccctctgtggagaaagcggtccgcaaagtcatggcccagtatgcaagcaac
atcacctctgtgctgtgccagttccccagccagcagatcgccaacatcctggacagccac
gctgcaactctccagcggaaagcggaccgagaagttttcttcatgaacactcagagcatc
gtgcagctagtgcaaaggtaccggagtggaactcggggctacatgaagaccgtggtgtta
gatttattaaggaaatacctgcaagtggaacatcacttccaacaagcccactatgacaag
tgcgtgattaacctccgggagcagtttaagccagacatgtcacctgtgctcaactgcatc
ttctcccacgcgcaggtggccaagaagaaccagctggtgaccatgttaatcgatgagctg
tgtggtccagatccatcattgaccgatgagcttctctccattctcggtgaactcacccaa
ttgagcaaaagtgaacattgcaaagtagccttaagagccagacaggtactgatcgcctcc
cacctcccctcttatgaactcagacacaaccaagtagaatccattttcttgtctgccatt
gacatgtatggccaccagttctgcccagaaaacctcaagaaactgatcctgtctgaaacc
accatatttgatgttctgcccaattttttctaccatgctaaccaggtggtctgcatggca
tccctggaggtgtatgtccgaagaggctacattgcctacgagctaaacagcctgcagcac
cggcagcttcctgatggcacctgtgttgtggaattccagttcatgctgccctcgtctcat
ccgaacagaatgtctcttccggtcagcatcaacaaccctgacctgctgcggcacagcacc
gagctcttcatggacagcggcttctcccccctctgccagaggatgggcgccatggtcgcc
ttccacagatttgaggactttgtcagaaacttcgatgaagtcatctcctgcttcgccaac
ctggctaaggagagcccactgttcagcgaggcgcggtccatgctctactcagaggattgc
aagtgcctcaaggacgagcccatccacattttgaacgttgccatccagtacgccgaccac
ctggaggacgaggagctggtccccatcttccggacgtttgtgcaatccaagaagctcgtc
cttgtggaatacggcctccggagaatcaccttcctcatcgcccaggagagagaatttccc
aagtttttcaccttcagagcacgagatgagtttgccgaagacaggatttaccgccatttg
gagcccgccctggccttccagctggagctgaatcgaatgcggaactttgagctgaaggcc
gtgccctgcgccaaccacaagatgcacctgtacctgggcgcggcgcgagtgaaggagggc
accgaagtgaccgactaccggttcttcatccgcgccatcatcaggcactcggacctcatc
accaaggaagcctccttcgagtacctgcagaacgagggggagcggctgctcttggaagcc
atggacgagctggaggtggccttcaacaacaccagcgtacgcaccgactgcaaccacatc
ttcctcaacttcgtgcccacggtcatcatggacccttccaagatcgaggagtcggtccgc
tccatggtgatgaggtacggcagccggctctggaagctccgggtcctgcaggccgaggtc
aagatcaacatccgcatgaccccaactggcaccgcgatccccatccgtctcttcctgacc
aacgagtctggctactatctggacatcagcctttacaaagaagtgactgatcccaggagc
ggaaacatcatgttccactccttcgggaacaagcagggcgcccagcacgggatgctgatc
aacacgccctacgtgaccaaagacttgctccaggccaagagatttcaggctcagtctctg
ggaaccacctacatctatgacttcccagaaatgttcaaacaggctctctacaagctgtgg
ggctcctccgaaaagcagcccaaggacattttgacctgcaccgagctcgtgctggactct
caggggcagctggtggagatgaacaggctcccgggagggaatgaggtgggcatggtggct
ttcaaaatgctgctcaagacccgagagtaccccaacggccgctacatcatcgtcatcggc
aacgacatcaccttccggatcggctctttcggccaggaggaggacctgctgttcctgcgc
gtgtcccagctggcccgggccgagggcatccccaagatctacctctccgccaacagtggg
gcccgcatcggcctggccgaagagatccggcacatgttccacgtggcctgggtcgacccc
gaggacccctgcaagggatttaaatacctctacctgactccacaagactacaccaagatc
agctccctgaactcggtccattgcatgcacgtggaagaggaaggagagtccaggtacgtc
atcacggacatcatcgggaaggatgatgggctcggcgtggagaacctgaggggctcgggc
acgattgctggggagtcctctctggcttatgaggaaattattaccatcagcatggtgacc
tgccgggctatcggaattggtgcctacctggtgcggctgggacagcgagtgatacaggtg
gataattcccatatcatcctgacaggagcgagtgctttaaataaggtcctcggccgggaa
gtttatacctcaaataaccagttgggtggcgtgcagatcatgcattttaatgggatttcc
cacatcaccgttccagatgactttgagggagtttacaccatcttggagtggctctcctac
atgcccaaggacacacatagcccagtgcccatcatcacacctatcgaccccattgaccga
gaaattgagttcactccttccaaagccccctacgacccccgctggatgctagcaggaagg
tctcatccaactgtgaagggatcctggcaaagtggcttctttgaccagaacagcttcaag
gagatcatggagccttgggcccaaaccgtggtgaccggccgagcaaggttggggggaatt
cctgtcggggtgattgccgtggagacgcggaccgtggagatggtggtccccgccgatcct
gctaatctggattctgaagctaagataatccaacaggcaggacaggtgtggtttccagac
tcggcctttaaaaccgcccaagctatcaaggatttcaaccgcgagaaattgcctctgatg
atctttgccaactggagaggattctctgggggcatgaaggacatgtatgaccaggtgttg
aagtttggagcttatatagtagatggtctcagacagtacaagcagcccatcctcatctac
atccccccatacgctgagctccgtggaggctcctgggtggtcattgacccaaccatcaac
cctctgtgcatggagatgtacgcagacaaggagagcagaggcggggttttggaacccgaa
ggaaccgtggagatcaagttccggaaaaaagacctgataaaaaccatgaggaggattgac
agcatttacatgaaattggtggaacagctgggggcagaagatctgccagaaaaggaccgg
aaggacctggagagcaagctgcgcgcccgggaagagcacctgctacctgtctaccaccag
gtggcggtgcagtttgcggatctccacgacacgccagggaggatgcaggagaagggcgtc
atttcagacattctcgagtggaaaacgtcgcgcacattcctgtactggcgcctccgccgc
ctgctcctcgaggacatcgtcaagaacaagatcctgcaggccaacggcgagctcagccac
gtgcacatccagtccatgctgcgccgctggttcatggagaccgagggcgccgtcaaggga
tacctctgggacaacaaccaggtggtggtggagtggctggagaagcacctgcagcaggag
gacggcctgcactcggccattcgggagaacatcaagtgcctgaagcgggactctgtcctc
aagaccatccgagggctggttcaggacaaccccgaggttgccgtggactgtgtgatccac
atgacccagcacatcagccccgcggacagggcccagatcgcccacctcctagccaccatg
gagagcccggcctccacctga
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integrated database retrieval system
