Candidatus Sulfidibacterium hydrothermale: LA303_00525
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Entry
LA303_00525 CDS
T07944
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
shyr
Candidatus Sulfidibacterium hydrothermale
Pathway
shyr00270
Cysteine and methionine metabolism
shyr00450
Selenocompound metabolism
shyr00670
One carbon pool by folate
shyr01100
Metabolic pathways
shyr01110
Biosynthesis of secondary metabolites
shyr01230
Biosynthesis of amino acids
shyr04980
Cobalamin transport and metabolism
shyr04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
shyr00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LA303_00525 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
LA303_00525 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
LA303_00525 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
LA303_00525 (metH)
04980 Cobalamin transport and metabolism
LA303_00525 (metH)
Enzymes [BR:
shyr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
LA303_00525 (metH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
HemY_N
Motif
Other DBs
NCBI-ProteinID:
UBM62480
LinkDB
All DBs
Position
124321..128037
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AA seq
1238 aa
AA seq
DB search
MPTDKAITINTMTKTKPDIREELKKRVLVLDGAMGTMIQRYHLEEKDYRGERFKNVKQLL
KGNNDLLNITQPHIIREIHEQYLEAGADIIETNTFNGTRISQSDYGLEKYVDEMNFQAAR
IAREAADKFTKKTPDKPRFVAGAMGPTNKTASMSPKVNDPGYRDVTFDDLMKDYYAQASA
LLKGGADILLVETIFDTLNAKAALFAIEKIMEEKGEKIPVMVSGTITDNSGRTLSGQTLE
AFFTSIKHIELLSVGLNCSLGAEQMRPYLAELSRIAPFPVSVYPNAGLPNQFGEYDESPH
KMAGHIKEFLDNRYANIVGGCCGTTPEHIREMVQLAEKAQTRQIPPARHVTELSGLEPVV
IDKNKNFVNIGERTNVSGSRRFARLIREGKYEEALSVARDQVENGAQILDVSMDDGMLDA
KTEMVKFLNMMASDPEISRLPVMIDSSKWEVIEAGLKCLQGKGIVNSISLKNGEEEFLEH
ARIIRDFGAAVVVMAFDEKGQAATYEDRIRVCKRAYDLLTQKIAFPPEDIIFDPNILAIG
TGMEEHSNYAVDFIKATRWIKENLPYARVSGGVSNLSFAFRGNNTVREAINSVFLYHAIK
AGMDMGIVNPGMLQVYDEIEPELRTLAEDVILNRRKDATERLLAFAEKIKDKSGKKVVKD
NAWRKEPVEKRLEHALIKGITEYIEEDVEEARKKYPRALHVIEQPLMAGMNRVGDLFGEG
KMFLPQVVKSARVMKQAVSYLLPYIEAEKEEGDTANAGKVVLATVKGDVHDIGKNIVGVV
LSCNNYEVIDLGVMVPAEKILEIAENEKADVVGLSGLITPSLEEMVHVAGEMKRKGLKMP
LLIGGATTSAIHTAVKIAPGYDQPVIHVRDASKVTGVLSRLFSPSEREKFVDEIQRSYEK
LRNDHFGRQQKKEYISLQEARDNRLKIEWKKEDLAVPRFTGIQYFDDYPLEDLVPFIDWT
FFFHTWKITGKYPAIFDDPVKGEEARKLYNDGKKMLDRILSEKWLQARGAIGIFAAQAVG
DSVEVFSTDQKEKLADFHFLRNQEKKEPGVPNLCLSDFIAPRETGLTDYLGFFALTTGIG
IEKHLQKFEKEGDDYQAIMLKVMADRLAEAFAEQMHWRIRKEIWGYAPDENLEVKNILRE
KYRGIRPAPGYPACPEHSEKKTLFDLLQAEEKTGIQLTENFAMYPAASVSGYYFAHPEAR
YFNVGRLLPDQIEDYARRKNLPVEKVKILLNMNLAEKE
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atgccgacggacaaagccataactatcaataccatgaccaaaaccaaaccagacatacgg
gaagaattaaaaaaacgggtacttgttttggatggtgccatgggcaccatgattcaacgg
tatcatctggaagagaaagactaccggggcgaacgttttaaaaacgtgaaacaattgctc
aaaggcaataatgacctgctcaacatcacgcaaccgcatattatccgcgaaattcacgaa
caataccttgaggccggagccgatattatcgaaaccaacacctttaacggaacccgtatt
tcgcaaagcgattacggtttggaaaaatatgtggacgaaatgaactttcaggctgcccgg
attgcccgtgaagccgctgataaatttaccaaaaaaacgccggacaaaccccgttttgtt
gccggagccatgggcccgaccaacaaaaccgcttccatgtctcccaaagtcaacgaccct
ggctaccgcgatgtcactttcgacgatctcatgaaagattactatgcacaggcttccgct
ttgctgaaaggaggtgctgacatcttgctcgtcgaaaccatttttgacacccttaatgcc
aaagcggcgctttttgccatcgaaaagatcatggaagaaaaaggggagaaaattccggta
atggtctctggaaccatcaccgacaacagcgggcgaaccctgtcaggacaaacactggaa
gctttttttacttccatcaagcatatcgaattgctcagcgtcgggttaaattgctctctg
ggcgccgagcaaatgcggccttatctggctgaattatcacgtattgctccttttcccgtg
agcgtttaccccaatgccggattgcctaaccaatttggtgaatacgatgaaagtccgcac
aaaatggccggccacatcaaagagtttctcgacaaccggtatgccaatattgtcggcggt
tgctgcgggactacgccggagcatatccgggaaatggtacaactggccgaaaaagcacaa
acgcgccagattcctcctgcccgtcatgtcaccgagcttagtggcctggaaccggtggtt
atcgacaaaaacaaaaactttgtcaatattggcgaacggaccaatgtaagcggttcccgc
cggtttgcccgccttatccgcgaaggaaaatatgaagaagcgctgtctgttgcccgcgat
caggtagaaaacggagctcaaattctggatgtaagcatggacgacgggatgctggacgcc
aaaaccgaaatggtgaaattcctgaacatgatggcttccgacccggaaatctccaggctg
cctgtgatgatcgactcttccaaatgggaagttattgaggccggattgaaatgtttgcag
ggaaaaggaattgtaaattccatcagcctgaaaaacggcgaagaagagtttctggagcat
gcccgtattattcgtgattttggagcagctgttgtggtaatggcttttgacgaaaaagga
caagcagcgacctacgaagaccgtatccgggtttgtaaaagggcttacgacctgttaaca
caaaaaatagcctttccgcccgaagacatcattttcgatcccaacattttggccatcggc
accggaatggaagaacacagcaactacgccgtagattttatcaaagccacccggtggatt
aaagaaaatcttccgtatgcccgggtgagcggcggcgtcagcaacctctcgtttgctttt
cgtggcaataataccgtacgcgaagccattaattcggtatttctctaccatgcgatcaaa
gccggaatggacatgggcattgttaaccccgggatgctgcaggtttacgatgagatagaa
cctgaactgcggacactggctgaagatgtaatacttaaccgccggaaagatgcaaccgaa
aggcttctggcttttgcagaaaaaataaaagacaaaagcgggaaaaaagttgtaaaagac
aatgcctggcgtaaagaacccgtggaaaaaaggctggaacatgcactgataaaaggaatc
accgaatacatcgaagaagatgtggaagaagcccggaaaaaatatccgagagcacttcat
gtgattgaacaaccgctgatggccgggatgaatcgtgtgggcgacctttttggagaagga
aaaatgtttttgccccaggtggtaaaaagtgcccgggtgatgaaacaagccgtatcgtat
ctgctgccctatatcgaggcggaaaaagaagaaggcgatacggccaacgccggaaaagtg
gtgctggcaaccgtgaaaggcgatgtgcatgatatcggaaaaaacatcgtgggcgtggtt
ctctcgtgtaacaactatgaagtaattgatttgggcgtcatggtccctgccgaaaaaatc
ctggaaattgcagaaaacgaaaaagctgacgttgtcggtctcagcggcttgatcaccccg
tcgctggaagaaatggtacatgttgccggcgagatgaaacgcaaaggattaaaaatgccg
ctgctcatcggcggtgctaccacttcagccattcataccgctgtaaaaattgctccggga
tacgaccagccggtcattcatgtacgtgatgcttctaaagttaccggcgtgctttcccgg
ctgttttctccttctgaacgagaaaaattcgttgacgaaattcagcgttcttatgaaaaa
ctaagaaacgatcattttggccggcaacaaaagaaggaatacatcagcctgcaggaagcc
cgtgataaccggttgaaaattgaatggaaaaaagaagatcttgctgttccccggtttacg
ggaatacaatattttgatgattatcctttggaagatttggttccttttatcgactggact
ttctttttccatacctggaagatcaccggaaaatatccggctatttttgatgatccggtc
aagggggaagaagcccggaaactttacaacgacggcaaaaagatgctggaccgtatcctt
tcggagaagtggttacaagcacgtggagccattggcatttttgctgcccaggctgtcgga
gacagtgtggaagttttttcaaccgaccaaaaagaaaaactggctgattttcactttctg
cgcaatcaggagaaaaaagagcccggcgttcccaatctttgtctttctgacttcattgct
ccccgcgaaaccggtttaaccgattatctgggcttttttgccctgactaccggcatcggt
atcgagaaacaccttcaaaaatttgaaaaagagggagatgactaccaagccattatgtta
aaagtaatggctgaccggctggcagaagcttttgctgaacaaatgcactggcgtatccgg
aaagagatttggggttatgctccggatgaaaatctggaggttaaaaatattctccgtgaa
aaataccgcggaatccgtccggcaccgggctatcctgcctgccccgaacattccgaaaaa
aagacactttttgatctgctacaggcagaagaaaaaaccggtatccagctcaccgagaat
tttgccatgtatccggcagcttcggtcagcggatactactttgcccatccggaagcccgt
tatttcaatgtgggccggctcttgcccgaccagatagaagattatgcccgccggaaaaat
cttccggtagaaaaagtcaaaatattactgaacatgaatcttgcggaaaaagaataa
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