Streptomyces inhibens: KI385_13520
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Entry
KI385_13520 CDS
T08140
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sine
Streptomyces inhibens
Pathway
sine00010
Glycolysis / Gluconeogenesis
sine00020
Citrate cycle (TCA cycle)
sine00620
Pyruvate metabolism
sine00785
Lipoic acid metabolism
sine01100
Metabolic pathways
sine01110
Biosynthesis of secondary metabolites
sine01120
Microbial metabolism in diverse environments
sine01200
Carbon metabolism
sine01210
2-Oxocarboxylic acid metabolism
Module
sine_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sine00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KI385_13520 (aceE)
00020 Citrate cycle (TCA cycle)
KI385_13520 (aceE)
00620 Pyruvate metabolism
KI385_13520 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KI385_13520 (aceE)
Enzymes [BR:
sine01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KI385_13520 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
UKY49727
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Position
2913049..2915721
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AA seq
890 aa
AA seq
DB search
MPDPVRTTYSQLDQIPDRDPEETAEWRESLDAVTKAAGPHRAAYLMRRALEHTGAPGLAP
LETDYVNTIPTSAEPGLPGDEAMEARITAWNRWNAAAMVTRGSRFGVGGHIATFASAAWL
YETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLSEQQLDNFRQEAGGNGLPS
YPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLANRGIKDTANSHVWAFLGDGEMDEP
ESTAALALAAREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSLWGS
AWDELFQLDTTGALVRRLRQVPDAQFQTYATRDVAYIREHFFGAEPALVEMAKVLTDAKI
AECFHTSRGGHEARKVYAAYKAAVEYQGAPTVILAQTVKGYTLGAGFESKNANHQMKKLS
GKEFRAMRDLLDLPIPDSKLDEELVPYGHPGADSPEVRYLQERRASLGGPAPARRVHPVP
ALPAPEERAFKALYKGSGKQEMATTMAFVRLVKDLIRDKQTGKRWVPIVPDEARTFGMES
LFPSVGIYSPKGQTYEPVDRDQLMYYKEATDGQILNEGITEAGAMADFIAAASSYATHGE
PMIPFYIFYSMFGWQRTADQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLIAS
TNPASLNYDPAFAYEIAVIVKDGLRRMYGENPENVFYYLTVYNEPKVQPAMPEGVEEGIL
RGLYRFKEAALDGSAASEAPRLQLLGSGTAIHWALEAQQLLADDWGVAADVWSVPSWTEL
RRDALECDAARLEGEDRIPYVTRALAGAPGPVVAVSDWMRAVPDQIAPWVEQDWTSIGTD
GFGLSDTREAARRHFGVDPQSVVVQALASLARRGEVKLETVKEAKERYGL
NT seq
2673 nt
NT seq
+upstream
nt +downstream
nt
atgcccgatcccgtacgtaccacgtacagccagctcgaccagatcccggaccgggacccc
gaggagaccgccgagtggcgcgaatcgcttgacgccgtcaccaaggccgcgggcccgcac
cgtgccgcgtatctcatgcgccgcgcgctggagcacaccggtgcccccgggctcgcgccc
ctggagacggactacgtcaacaccatcccgacctccgccgagcccggcctcccgggcgac
gaggcgatggaggccaggatcaccgcctggaaccgctggaacgccgccgccatggtgacg
cgcggctcgcggttcggcgtcggcggccacatcgcgaccttcgcgtccgccgcctggctg
tacgagaccggcttcaaccacttcttccgcggcaaggagggcgacggcagcggcgaccag
ctctacatccagggccatgcctcgcccggcatctacgcccgcgccttcctcgacggccgc
ctttccgagcagcagctcgacaacttccgccaggaggccggcggcaacggtctgccctcc
tacccgcacccgcggcgcctgccctggctgtgggagttcccgaccgtctccatgggcctc
ggcccgctctccgcgatctaccaggcgcgcttcaaccgctacctggccaaccgcggcatc
aaggacaccgccaactcacacgtctgggcgttcctgggcgacggcgagatggacgagccc
gagtcgaccgccgcactcgccctggcggcccgcgagggtctggacaacctgaccttcgtc
atcaactgcaacctccagcgcctcgacggcccggtccgcgccaacttcaagatcgttcag
gagctggaggcccagttccgcggcgccggctggaacgtcgtcaagtcgctgtggggctcc
gcctgggacgagctgttccagctcgacaccaccggtgcgctcgtccgccgtctgcgccag
gtgccggacgcgcagttccagacgtacgccacccgcgacgtcgcctacatccgcgagcac
ttcttcggcgcagagccggccctggtcgagatggccaaggtgctgaccgacgcgaagatc
gccgagtgcttccacacctcccgcggcggccacgaggcccgcaaggtgtacgcggcttac
aaggcggccgtggagtaccagggcgcgccgaccgtgatcctcgcgcagaccgtcaagggc
tacaccctgggcgccggcttcgagtccaagaacgccaaccaccagatgaagaagctctcg
ggcaaggagttccgcgccatgcgcgacctgctcgaccttcccatcccggactccaagctg
gacgaggagctcgttccgtacggccacccgggcgccgactcccccgaggtccgctacctt
caggagcgccgcgcgtccctcggcggtccggccccggcccgccgggtccacccggtcccg
gcgctgcccgcgcccgaggagcgcgccttcaaggcgctgtacaagggctccggcaagcag
gagatggccaccaccatggccttcgtccgcctcgtcaaggacctgatacgggacaagcag
accggcaagcgctgggtgccgatcgttcccgacgaggcccgtaccttcggtatggagtcg
ctgttcccctcggtcggcatctactcgcccaagggccagacgtacgagccggtcgaccgc
gaccagctgatgtactacaaggaagccaccgacggccagattctcaacgagggcatcacc
gaggccggcgccatggccgacttcatcgccgccgcctcgtcgtacgcgacgcacggcgag
ccgatgatccccttctacatcttctactcgatgttcggctggcagcgcaccgccgaccag
atgtggcagctcgccgaccagctcggcaagggcttcatcgtcggcgccaccgccggccgt
accaccctgaccggtgagggtcttcagcacgccgacggccactcgcacctgatcgcgtcc
acgaacccggcgtccctcaactacgacccggccttcgcgtacgagatcgcggtgatcgtc
aaggacggtctgcgccggatgtacggcgagaaccccgagaacgtcttctactacctcacc
gtctacaacgagcccaaggtccagccggccatgcccgagggcgtcgaagagggcatcctg
cgcggcctgtaccgcttcaaggaggccgctctcgacgggtccgcggcttccgaggccccc
cgcctccagctcctcggctcgggtacggccatccactgggccctggaggcgcagcagttg
ctggccgacgactggggcgtagcggcggacgtctggtcggtgccgtcctggacggagctg
cgccgcgacgccctggagtgcgacgccgcccgtctggagggcgaggaccggatcccgtac
gtcacccgtgcactggccggcgcccccggcccggtcgtcgcggtcagtgactggatgcgt
gccgtcccggaccagatcgccccctgggtcgagcaggactggacctccatcggcaccgac
ggtttcggtctctccgacacccgcgaggcggcccgccgccacttcggcgtcgacccgcag
tcggtggtcgtccaggcgctggcgtccctcgcccgccgcggcgaggtcaagttggagacc
gtcaaggaggccaaggagcggtacggcctgtga
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