Streptomyces inhibens: KI385_15075
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Entry
KI385_15075 CDS
T08140
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sine
Streptomyces inhibens
Pathway
sine00010
Glycolysis / Gluconeogenesis
sine00020
Citrate cycle (TCA cycle)
sine00620
Pyruvate metabolism
sine00785
Lipoic acid metabolism
sine01100
Metabolic pathways
sine01110
Biosynthesis of secondary metabolites
sine01120
Microbial metabolism in diverse environments
sine01200
Carbon metabolism
sine01210
2-Oxocarboxylic acid metabolism
Module
sine_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sine00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KI385_15075 (aceE)
00020 Citrate cycle (TCA cycle)
KI385_15075 (aceE)
00620 Pyruvate metabolism
KI385_15075 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KI385_15075 (aceE)
Enzymes [BR:
sine01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KI385_15075 (aceE)
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
UKY50011
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All DBs
Position
3253255..3255987
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AA seq
910 aa
AA seq
DB search
MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGVYARAFLLDRLSEGQLDAFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIMQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGILVNKLNSTPDGQFQTYATETGAYIRQHFFGDDHRLR
AMVENMTDDQILHLGRGGHDHKKIYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVEDLKGFRDRLHLPIPDKDLEDGLPPYYHPGRSSEEIQYMHDRRKALGGYVP
TRVVRAKPLPLPDDKAYAGAKKGSGQQKIATTMAFVRVLKDLMRDKEIGKRFVPIAPDEY
RTFGMDAFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGITEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSRGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVAYDPAYGYEIAQIVKDGLRRMYGEHAEDVFYYLTVYNEPILHPAEPA
DVDVEGILKGLHRVKPGEKGEHAAQILASGVAVPWAIEAQQILADEWNVKADVWSATSWN
ELRRDAVEVEEHNLLHPEEEQRVPYVTHKLQGAEGPKVAVSDWMRSVPDQISRWVPGTYQ
SLGADGFGFADTRGAARRFFHIDAQSIVLSVLTELAKEGKVDRSLLKQAIDRYQLLDVTA
ADAGEAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgaaacccgatcatcattggcggccttcccagccaggtcccg
gacttcgatcccgaagagacccaggaatggctcgactcgctcgacgctgccgtcgatgag
cgaggccgggaacgtgcccgctacctcatgcttcgtctgatcgagcgtgcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacaccatcgcgaccaaggac
gagccgttcttcccgggcaacgaggagatcgagcgcaaggtcctgaacgcgacccggtgg
aacgccgccgtcatggtctcgcgcgcccagcgtccggggatcggcgtcggcggtcacatc
gccaccttcgcctcctccgcctccctctacgacgtgggcttcaaccacttcttccggggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccatgcctcgcccggtgtc
tatgcccgcgcgttcctcctggaccgactgtccgagggccagctcgacgccttccgccag
gagaagtccaaggcccccaacggcctgtccagctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgctcggtgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgccgacacctccaagtcgcacgtatgg
gcctacctcggcgacggcgagatggacgagcccgagtcgctcggccagctgtccatcgcc
gcccgtgagggcctggacaacctgaccttcgtcgtcaactgcaacctgcagcgcctggac
ggcccggtccgcggcaacggcaagatcatgcaggagctggagtcgcagttccgcggtgcc
ggctggaacgtcatcaagctggtgtgggaccgcagctgggacccgctgctcgcgcaggac
cgcgacggcatcctggtcaacaagctcaacagcacgccggacggtcagttccagacgtac
gccaccgagaccggtgcctacatccgccagcacttcttcggcgacgaccaccgcctgcgc
gcgatggtcgagaacatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
cacaagaagatctacgcggcgtatgcggcggccaaggcgcacaagggccagccgacggtg
atcctcgcgcagaccgtcaagggctggacgctcggcccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgaggacctcaagggcttccgtgaccggctgcac
ctgccgatcccggacaaggacctggaggacggcctgccgccgtactaccacccgggccgc
agctccgaagagatccagtacatgcacgaccgccgcaaggcgctgggcggctatgtgccc
acccgtgtcgtgcgcgccaagccgctgccgctgccggacgacaaggcgtacgcgggtgcc
aagaagggctcgggacagcagaagatcgccacgaccatggcgttcgtccgtgtcctgaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgccgatcgcgcccgacgagtac
cgcaccttcggcatggacgcgttcttcccgtcggccaagatctacaacccgctgggccag
cagtacgagtcggtcgaccgtgaactgctcctggcgtacaaggagtcgccgaccggtcag
atgctgcacgacggcatcaccgaggcgggctgcacggcctcgctgatcgcggcgggctcc
gcctacgccacgcacggcgagccgctgatcccggtctatgtcttctactcgatgttcggg
ttccagcgcaccggtgaccagttctggcagatggccgaccagctctcgcggggcttcgtg
ctcggcgcgaccgccggccgtacgacgctgaccggtgagggtctgcagcacgccgacggc
cactcccagctgctggcctcgacgaacccggcctgtgtcgcctacgacccggcctacggt
tacgagatcgcgcagatcgtcaaggacggtctgcggcggatgtacggcgagcacgccgag
gacgtcttctactacctgaccgtctacaacgagccgatcctgcacccggcggagccggcc
gacgtcgacgtcgagggcatcctcaagggtctgcaccgcgtcaagcccggcgagaagggc
gagcacgccgcccagatcctcgcctcgggtgtcgcggtgccgtgggcgatcgaggcccag
cagatcctcgcggacgagtggaacgtcaaggccgatgtctggtcggcgacgtcctggaac
gagctgcgccgcgacgcggtggaggtcgaggagcacaaccttctgcacccggaggaggag
cagcgcgtcccgtatgtgacgcacaagctccagggcgccgagggcccgaaggtcgcggtc
tcggactggatgcgttcggttcccgaccagatctcgcgctgggttcccggcacgtaccag
tccctgggcgccgatggcttcggtttcgcggacacccgtggcgcggcccgtcgcttcttc
cacatcgacgcgcagtccatcgtcctgagcgtgctcaccgagctcgccaaggagggcaag
gtcgaccggtcgctgctgaagcaggcgatcgaccgttaccagctcctggacgtcacggcc
gccgacgcgggtgaggccggcggcgacgcctga
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