KEGG   Streptomyces inhibens: KI385_15215
Entry
KI385_15215       CDS       T08140                                 
Name
(GenBank) peptidase M15D vanX D-ala-D-ala dipeptidase
  KO
K08641  zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
Organism
sine  Streptomyces inhibens
Pathway
sine01502  Vancomycin resistance
sine02020  Two-component system
Brite
KEGG Orthology (KO) [BR:sine00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    KI385_15215
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    KI385_15215
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:sine01002]
    KI385_15215
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:sine01011]
    KI385_15215
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:sine01504]
    KI385_15215
Enzymes [BR:sine01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.13  Dipeptidases
    3.4.13.22  D-Ala-D-Ala dipeptidase
     KI385_15215
Peptidases and inhibitors [BR:sine01002]
 Metallo peptidases
  Family M15: zinc D-Ala-D-Ala carboxypeptidase family
   KI385_15215
Peptidoglycan biosynthesis and degradation proteins [BR:sine01011]
 Peptidoglycan biosynthesis and degradation
  Carboxypeptidase
   KI385_15215
Antimicrobial resistance genes [BR:sine01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
    KI385_15215
SSDB
Motif
Pfam: CN_hydrolase Peptidase_M15 VanY DUF6928
Other DBs
NCBI-ProteinID: UKY50038
LinkDB
Position
3285830..3287224
AA seq 464 aa
MLIAAAQFTSVPGDIEANAARMAALITEAAGRGAGLVVFSELALTHYDLRLIVADPAGLL
VLPDDARLAPVREACRASGVAAVVNAAGRAPEAGARPTIASFVYGPDGALLTRYDKMHLT
DQESEIFAPGATDGRFTLGGIRFALATCYDNSFPDVPARAAADGCRVYLASSFHDSAEGV
ARYAGLARDNGLQVLLANGTEVGSPGPACGLSGVWLPSGERVAAAAEWTEPVPGDGAELV
LSDARDRITLMSDPAVAAIPVKECGEPLVDVRTAAPTLLVAADRHDEQGAFAYLREGLLR
RLLAAQEALPDGLRLQFVEGYRPPGLQRRYFEEYADELRAGFPEWDGARIHQAASRYVSP
PEIAPHSAGGAVDLTLVTADGADVDMGTPINASPEESDGACYTSAPGLPPAARANRRVLA
AALAASGLVNYPTEWWHWSYGDRYWALATGSDHALYAAKELAEQ
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgctcattgctgccgcacagttcacgtccgtaccgggcgatatcgaagccaacgccgcg
cggatggccgcactcatcaccgaggccgccgggcgtggcgccggtctggtggtgttctcc
gaactcgccctgacgcactacgacctgcgtctgatagtcgctgatccggcggggctgctg
gtcctgcccgacgatgcccggctggcccccgtacgggaggcgtgccgggcgagtggggtc
gcggcggtcgtgaacgccgcgggccgggcccccgaggccggggcccggccgaccatcgcc
tcgttcgtctacgggccggacggcgcgctgctcacccgctacgacaagatgcacctgacc
gatcaggagagcgagatcttcgcgccgggcgccaccgacggccgcttcaccctgggcggc
atccggttcgcgctcgccacctgttacgacaacagctttcccgacgttccggctcgggcc
gcggcggacggctgccgggtgtatctcgccagctccttccatgactcggccgagggcgtg
gcgcggtatgccgggctggcccgggacaacggactgcaggtactgctcgccaatggcacg
gaggtcggcagccccggcccggcctgcggcctcagcggcgtctggctgccgtccggcgag
cgggtggcggcggccgccgagtggacggagccggtgccgggcgacggggcggagctggtg
ctgagcgatgcccgggaccggatcacgctgatgtcggatccggcggtggcggcgatcccc
gtcaaggagtgcggtgagccgctggtggacgtacggaccgcggcgcccacgctcctggtg
gccgcggaccggcacgacgagcagggcgcgttcgcgtatctgcgcgaggggctgctgcgg
cggctgctggcggcgcaggaggcgctgccggacgggctgcggctgcagttcgtcgagggc
taccgcccgccggggctgcagcgccgctacttcgaggagtatgcggacgagctgcgcgcc
gggttccccgagtgggacggggcgcgtatccatcaggccgccagccgttatgtctcgccg
ccggagatcgcaccgcacagtgcgggtggcgcggtggatctcacgctcgtcaccgcggac
ggcgcagatgtcgacatggggacaccgatcaatgcctccccggaggagagcgacggcgcc
tgctacacgagcgctccggggctgccgcccgccgcccgcgccaaccgacgggtgctggcc
gccgcactggccgcgtccggtctggtcaactacccgacggagtggtggcactggtcctac
ggcgaccgctactgggcgctggcgaccggctcggaccatgcgctgtacgccgcgaaggag
ctggccgagcagtga

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