KEGG   Streptomyces inhibens: KI385_25175
Entry
KI385_25175       CDS       T08140                                 
Name
(GenBank) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
sine  Streptomyces inhibens
Pathway
sine00253  Tetracycline biosynthesis
sine01056  Biosynthesis of type II polyketide backbone
sine01100  Metabolic pathways
sine01110  Biosynthesis of secondary metabolites
Module
sine_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:sine00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    KI385_25175
   00253 Tetracycline biosynthesis
    KI385_25175
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:sine01004]
    KI385_25175
   01008 Polyketide biosynthesis proteins [BR:sine01008]
    KI385_25175
Enzymes [BR:sine01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     KI385_25175
    2.3.1.260  tetracycline polyketide synthase
     KI385_25175
Lipid biosynthesis proteins [BR:sine01004]
 Polyketide synthase
  Component type
   KI385_25175
Polyketide biosynthesis proteins [BR:sine01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     KI385_25175
    Nonaketide PKS
     KI385_25175
    Decaketide PKS
     KI385_25175
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C
Other DBs
NCBI-ProteinID: UKY51774
LinkDB
Position
complement(5500681..5501961)
AA seq 426 aa
MAAGGDTRRVVVTGIGVVAPGGIGTKAYWDLLTNGRTATRTISLFDATPFRSRVAAECDF
DPFMAGLTQRQVRMWDRTTQFAVVAAREAMSDSKILGELNPVRTGVMLGTACGMTMSLDS
EYAVVSDEGRTWHVDDAHGSPYLYDYFLPSSMAVEVAWLADAQGPVGVVSTGCTSGIDVL
GHAVDLIRDGEAEVMISGASDAAISPITVACFDAIKATTPRNDEPGTASRPFDRTRNGFA
LGEGSAVFVLEELEHAKRRGAHIYCEISGHSTHCNAYSMTGLRSDGVELAQSITKAMDQA
KVRPEQIGYVNAHGSSTKQNDRHETMAYKVALGEHAYSTPISSIKSMIGHSLGAICSLEV
AASALTIEHSIIPPTANLHEPDPECDLDYVPLVAREKNVDVVLSVASGFGGFQSAIVLTK
PEGSRA
NT seq 1281 nt   +upstreamnt  +downstreamnt
gtggcagcaggaggcgacacgcggcgcgtggtcgtaacagggatcggagtggtggcgccc
ggcggcatcggaaccaaggcctactgggatctgctgaccaacggccggacggcgacccgc
accatctccctcttcgacgcgacgccgttcaggtccagggtggccgccgagtgcgacttc
gacccgttcatggcgggcctgacgcagcgacaggtccggatgtgggaccggaccacccag
ttcgccgtcgtggccgcgcgggaagcgatgtccgacagcaagatcctgggtgaactcaat
cccgtccgcaccggcgtgatgttgggtaccgcctgcggcatgacgatgagtctcgacagt
gagtacgccgtcgtcagcgacgagggccgcacctggcacgtcgacgacgcacatggatcg
ccgtatctctacgactactttctgccctcctccatggccgtcgaggtcgcctggctggca
gacgcgcagggaccggtcggggtggtgtcgaccggctgcacctccggaatcgacgtactc
ggccatgccgtcgatctgatccgtgacggtgaagcggaggtgatgatctccggcgcctcc
gacgccgccatctctccgatcaccgtcgcctgcttcgacgcgatcaaggcgaccaccccc
cgcaatgacgaaccgggcaccgcctcccggcccttcgaccgcacccgtaacggattcgcg
ctgggcgaggggtcggcggtcttcgtactggaggagctggagcacgccaagcgccgtggg
gcccacatctactgcgagatctccgggcacagcacgcactgcaacgcctacagcatgacc
gggctgcgctccgacggcgtggagctggcgcagtccatcaccaaggccatggatcaggca
aaggtccggcccgagcagatcggctacgtcaacgcgcacggctcgtcgaccaagcagaac
gaccggcacgagaccatggcgtacaaagtcgccctcggcgagcacgcctactcgacgccg
atcagctcgatcaagtcgatgatcgggcactcgctgggcgcgatctgctcgctggaggtg
gccgcctccgccctgaccatcgagcactcgatcatcccgcccaccgccaatctgcacgag
ccggaccccgagtgcgacctggactatgtgccgctggtcgcccgcgagaagaacgtcgac
gtggtgctcagcgtcgccagtggattcggcggattccagagcgcgatcgtcctgaccaaa
cctgaagggagccgggcatga

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