Streptococcus iners: PW252_10010
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Entry
PW252_10010 CDS
T10964
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sins Streptococcus iners
Pathway
sins00270
Cysteine and methionine metabolism
sins00480
Glutathione metabolism
sins01100
Metabolic pathways
sins01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sins00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
PW252_10010 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
PW252_10010 (gshAB)
Enzymes [BR:
sins01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
PW252_10010 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
GARS_A
RimK
ATPgrasp_ST
Dala_Dala_lig_C
ATP-grasp_3
bCoV_lipid_BD
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
WNY50892
UniProt:
A0AA96VKZ1
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All DBs
Position
2065598..2067838
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AA seq
746 aa
AA seq
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MLQKLSPNSPILQATFGLERESLRINSDNRVAQTPHPEKLGSRSFHPYIQTDYSEPQLEL
ITPVAHSTKEARRFLGAITDVAVRSMEKTEYLWPLSMPPVISADEIQIAQLESDYEYQYR
VGLAERYGKLLQSMSGIHYNFELGKDLTQQLFEVSDYDDLITFKNALYLKLAQNFLRYRW
LLTYLYGVSSLAEKGFLTEEIGCVRSIRNSNYGYVNAPDVHISFSSLEQYVTDIEQAVAS
GQLSAEKEFYSAVRLRGAKTSRDFLTKGITYLEFRNFDLNPFETLAISQETLDTTHLFAL
ALLWLDDMEQVDKELAQAADLNNRIALSHPHTPLPAEADANPILTAMKSIVQHFGLDDYY
SQLIAQVEVALQDPRLTLSGKIAEQVEDGSLEHFGQQQGRLFHDYAWTAPYALKGYENME
LSTQMILFDAIQLGLHVEILDEEDQFLKLWHGDHVEYIKNGNMTSKDNYVIPLAMANKVV
TKKILNQAGFPVPAGAEFSNKEEALRYYGQVASSAIVVKPKSTNFGLGISIFKEPASQAD
YEKALDIAFSEDNHVLVEEFVAGTEYRFFILDGKCEAVLLRVAANVVGDGQSTIRELVEQ
KNQDPLRGRDHRSPLEIINLGDIELLMLEQQGYTPDTILPEGVQTFLRGNSNISTGGDSI
DMTDQMGQSYKQLAADMATAMGAWACGVDLIIPNRTKPASKEDPNCTCIELNFNPAMYLH
TYTYAGPGQSITPKILRKLFPQLKTG
NT seq
2241 nt
NT seq
+upstream
nt +downstream
nt
atgttacagaaattatccccaaatagtcccatcctccaagccacctttggtttggaacgg
gaatccttacgaataaatagcgacaaccgcgtggctcagacaccacatcctgaaaaactg
ggctcacgcagttttcacccctatattcagaccgattacagcgagccacaactagaactg
attacaccagtggctcattcgaccaaggaagcccgtcgtttcctcggagccatcacggat
gtagcggtgcggtctatggaaaaaacggaatacctatggcccctgtccatgccacctgtg
atttcagcggatgaaattcagattgctcagctggaaagtgactatgagtatcagtaccgt
gttggtttggcagaacgctatggtaagttgctccagtctatgtcaggcatccactacaac
ttcgagctcggcaaggacctgacccagcaactctttgaagtgagcgattacgacgacctc
atcaccttcaaaaacgccctctatctcaagctggctcagaatttcctacgctaccgctgg
ctcttgacctacctctacggagttagcagtctggcagaaaaaggatttttgacagaggaa
attggctgcgtgcggtccattcgcaattccaactacggctatgtcaacgcccctgatgtc
cacatctccttctcttctttggagcaatatgtgaccgacatcgagcaggcggttgctagc
ggtcagctgtctgccgaaaaggaattttactctgcggttcgcctccgcggtgccaagacc
agccgggacttcttgaccaagggcattacctacttggagttccgcaacttcgacctcaac
cccttcgagactctggccattagccaagagacacttgacaccacccacctctttgcccta
gcactactctggcttgatgacatggagcaggttgacaaggaattggcccaggcagcagac
ctcaacaaccgcatcgccctcagtcatccacacacacctctaccagcagaggcagacgcc
aaccctatcctgactgccatgaagtctatcgttcagcatttcggactggatgattactac
agtcagctcattgctcaggtagaggtagcccttcaagaccctcgtctgaccctttctgga
aaaatagcagagcaggttgaagacgggtctttggaacactttggccagcagcaaggtcga
ctctttcatgactatgcttggacagctccatacgccctcaagggctatgaaaacatggaa
ctctccacccagatgattctctttgacgccattcagctgggcttgcatgtcgagattttg
gatgaagaagaccagtttctcaaactctggcatggtgaccatgtcgagtacatcaaaaat
ggcaacatgacctccaaggacaactacgtcattcctctagccatggctaacaaggtcgtg
accaagaagatactgaaccaggctggttttccagtgcctgcgggagctgaattttctaac
aaggaagaggccctgcggtattatggacaggtagccagctctgctattgttgtcaaacca
aaatccaccaacttcggcctaggcatctctatcttcaaagagccagccagccaagcagac
tatgaaaaagctctggacatcgccttttcggaagacaatcatgtgctggtggaggagttc
gtagcgggaactgagtaccgcttcttcatcttggacggcaagtgcgaggctgtcctgctc
cgcgtcgcagccaatgtcgtaggggatgggcagtcaaccatccgtgaattagtagaacaa
aaaaaccaagatcccctgcggggccgtgaccaccgttcaccgcttgaaatcattaacttg
ggcgacatcgaactgctcatgttggaacaacagggctacacacctgacaccatcttgcct
gagggcgttcaaacctttctgcgtggcaattccaatatctcaacgggtggtgactccatc
gatatgaccgaccagatgggccagtcctacaagcaactggccgccgatatggcaactgct
atgggagcttgggcctgcggggtagatttgattatccccaaccgcaccaagccagccagc
aaggaagatccaaactgcacctgtatcgagcttaatttcaacccagccatgtacctgcat
acctatacctacgcaggacctggacagagtattacaccgaagatattgcggaagttgttt
cctcaactgaaaactggctag
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