Sulfurovum indicum: IMZ28_02945
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Entry
IMZ28_02945 CDS
T07193
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sinu
Sulfurovum indicum
Pathway
sinu00270
Cysteine and methionine metabolism
sinu00450
Selenocompound metabolism
sinu00670
One carbon pool by folate
sinu01100
Metabolic pathways
sinu01110
Biosynthesis of secondary metabolites
sinu01230
Biosynthesis of amino acids
sinu04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
sinu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
IMZ28_02945 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
IMZ28_02945 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
IMZ28_02945 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
IMZ28_02945 (metH)
04980 Cobalamin transport and metabolism
IMZ28_02945 (metH)
Enzymes [BR:
sinu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
IMZ28_02945 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tle3
Motif
Other DBs
NCBI-ProteinID:
QOR62451
UniProt:
A0A7M1S663
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Position
580061..583570
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AA seq
1169 aa
AA seq
DB search
MPVTETIKNLLEERILVIDGAMGTQIQDLEVPKEAWIDHRGKEQEGCNELLNDTAPELIG
RIHKRYAMAGADLIKTNTFGTMPWVLDEYEMGERAYELSKKGAQLVKSVCEEYSTENAPK
FVLGSIGPGTKLPSLGHIHYDEMYEGYKEVALGLIDGGCDLFLLETCQDPLQIKAALHAC
EDANKERNIKLPVMVSVTIELSGSMLIGTDATTIVTILEPFDILSLGFNCGTGPDQVKKH
LKVLSELCSIPISVHANAGLPQNRGGYTYYPMGPEEFTQKQLEFTAFDGVGFLGGCCGTT
PQHIHALKKAVETIRPKKPTGSIKPSIASLFNTVELFQEPAPLLIGERSNATGSKAFREL
IIAGDYEGTLTVGQAQVRDGAHCLDVNVEFAGRDGAKDMKEVMALYNQKIPLPLMPDATR
VGTMEAALKCIGGKPIINSVNLEDGEEKLDAICRLAKRFGAALVCLTIDETGMAKTTDTK
LAVAERLYDLCVNRHGIDPSNLIFDMLTFTVGSGDLEYRDAAIQTLEAIRELHRRHPEVG
STLGLSNISFGLDKNARIFLNSVFLHHCIQAGMTSVIINVKHIVPMAKMSQEDIDICEEL
LFHPDDNSLFKFIEHFSDKTLDDSSTDEAYEAMNIEEKIAKLLLDGDKERMIPLVEEARH
DIHPDKIVNEILIDAMKVVGELFGSGQMQLPFVLQSAETMKATVDYLNPYLTKQEKETDT
TLVIGTVKGDVHDVGKNLVDIILSNNGFKVINVGIKTELQEYLDVMKEKSIQAIGMSGLL
VKSTAVMKDNLEAMAEMGIEIPVLLGGAALTRSFVDDFCRPVYKGPIFYCRDAFDGVIAM
SRIEKYNEDPAAGLDTRLAGDMVKREERKEKKEVVIPPFEEIKMPPAVDIPTPPFWGRRV
LQKDDLDLDMIFDWVNQKTVIKMHWGYKSKGMDKAEYQKLLDETVYPAYERLKREFIQKD
LFDPTIIYGYYPVRSNDQELLVFDEREGWNIDANANREAFKEVVGRAEYAFSFPRQRRKP
YRALSDFFRHERHDVLPITCVSAGPKFSAYEKELYDAGKYLEYNMVHGFSVELAEALAEV
VHKQIRMDLGILKEDEKATLRDVRMNRYQGARYSFGYPACPDLEQSRIIFDLLKPEEFGI
ELSETFQIHPEQSTTALVVHHPKATYYAV
NT seq
3510 nt
NT seq
+upstream
nt +downstream
nt
ttgcctgtcacagaaacgattaaaaatcttttagaagagcgtatacttgttatcgatggt
gccatgggtacacagatacaggatcttgaagtacccaaagaggcatggatagaccacaga
ggtaaagagcaggaggggtgtaatgaactgctcaatgatactgctcccgaactgataggg
cgcatccataaacgatatgcaatggctggggcggatctcattaagaccaatactttcgga
acgatgccatgggtactcgatgagtatgaaatgggtgaacgtgcctatgaactttcgaaa
aaaggtgcacagcttgtaaagagtgtctgtgaagaatacagtacagaaaacgctccaaaa
tttgtacttggttccatcggtcccggaacgaaacttccctctttggggcatatccactat
gatgagatgtatgaagggtataaggaggtagctctggggctcattgatggtggctgtgat
ctctttttgcttgagacctgtcaggacccgctgcagatcaaagcggcactgcatgcctgt
gaagatgcgaataaagagagaaatataaaattgccagttatggtctcggtcactattgaa
ttaagcggttctatgcttattggaacagatgcaacaacaattgtaacgattttggagccg
ttcgatattctttcgctgggctttaactgcgggacaggacctgaccaggtaaaaaaacat
ctcaaagtgctttcagaactatgcagtattcctatttctgttcatgccaatgcgggactt
cctcagaatcggggaggatacacctactacccgatgggaccggaggaatttacccaaaaa
cagttggaatttacagcgtttgacggtgtggggtttctgggcggatgctgcggaacgaca
ccacagcatattcatgcactgaaaaaagcggttgagaccattagacctaaaaaacctaca
ggaagtatcaagccaagtattgcatcactctttaatacagtcgagctttttcaggaacct
gcaccgctgctcataggtgaacggagcaatgcaaccgggtccaaagcctttagagaactc
attattgccggagactatgaggggacactgacggtgggacaggcacaggtacgtgacgga
gcgcactgtctggatgtcaacgtggagtttgccggacgtgacggtgccaaagatatgaaa
gaggtgatggcactttacaatcaaaagatccctctgccgttgatgccggatgccacacgt
gtcggaacaatggaggccgcactcaagtgcattggaggaaagcctattatcaattcggtc
aaccttgaggatggagaagagaaacttgatgccatctgccgtcttgccaaacgttttgga
gcagctttggtttgtctgaccattgatgaaacgggaatggcaaagaccacagatacaaaa
ttggctgttgccgagcgtctttatgatctttgtgtcaaccggcacggtatcgacccaagc
aatcttattttcgatatgctcacatttacggtaggatctggagatcttgagtaccgtgat
gctgctattcagactcttgaggcgatcagggaactgcacaggcgtcatcctgaagtgggg
tcgacgctggggctttccaatatttcgttcggtttggacaaaaatgcacgtatcttcctg
aattctgttttccttcatcactgtattcaggcagggatgacctcggttatcatcaatgtc
aagcatattgtccctatggcaaagatgagccaggaagatattgatatatgtgaagaactg
ctctttcatcctgatgacaattcacttttcaagtttattgaacacttttctgacaaaaca
ctggatgattcgtccaccgatgaagcatatgaggcaatgaacatagaagagaagatcgcc
aaactgctgcttgacggggataaagagcgcatgatcccgttggttgaagaagcacgacat
gatattcatccggacaagattgtcaacgaaattcttattgatgcgatgaaggttgtgggt
gaactctttgggtcaggacagatgcagttgccgtttgtactccagtcggcagaaactatg
aaagcaacagttgattatcttaatccgtatctgaccaaacaggagaaagagactgatacg
acactggtgatcggtacggtcaaaggggatgtacatgatgttgggaagaatctggtcgat
attatcctctccaacaatggtttcaaggtgattaatgtcggaatcaaaaccgaacttcag
gagtatctggatgtaatgaaggaaaagtctattcaggctatcggtatgagtggattgctg
gtcaagtctactgctgtgatgaaagataatcttgaagcaatggctgagatgggaattgag
atccctgtgttgcttggaggtgctgctttgacacgcagttttgtcgatgacttctgccgc
cccgtatacaaaggaccgatcttctactgccgtgatgcttttgacggagtaattgcaatg
agccgcatagagaagtacaatgaagatccagctgccgggttggatacgcgtctggcagga
gatatggtgaaaagagaggagaggaaagagaaaaaagaggtggttattcctcctttcgaa
gagataaagatgccgcctgctgtagatattcccactccaccgttctggggcagaagagtg
cttcaaaaagatgatcttgatctcgatatgatctttgactgggttaatcagaaaacagtt
ataaagatgcactggggatacaaaagcaaagggatggacaaggcagaataccagaagctg
cttgatgaaacggtctatcctgcctatgagcgcctgaaaagagagtttatccaaaaagac
ctttttgatccgacgatcatttatgggtattatccggtacgaagcaatgaccaggaactt
ctggtctttgatgaacgtgaaggctggaatattgatgccaatgcgaaccgtgaagccttc
aaagaggtagtaggcagagcagaatatgccttctcttttccaagacagagaagaaaaccc
taccgtgcgctcagcgatttcttcaggcacgaaagacatgatgttcttcccattacctgt
gtgagtgccgggcctaagttttctgcatatgaaaaagagctttacgatgcaggaaaatac
ctggagtataatatggttcacggtttttccgtagaacttgccgaggctttggcagaagtg
gtacacaaacagatacgtatggatcttggtatcttgaaagaggatgaaaaagcaactctg
cgtgatgtacgcatgaaccgatatcagggagcacgctattcattcggctatccggcctgt
cccgatctggaacagagtcgtattatctttgatctgcttaaacctgaagagttcggtatc
gagctttctgaaacttttcagattcatcctgaacagagtacgacagctttggtggtgcat
caccctaaagcaacctactatgcagtgtaa
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