Scomber japonicus (chub mackerel): 128372984
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Entry
128372984 CDS
T09718
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
sjo
Scomber japonicus (chub mackerel)
Pathway
sjo00270
Cysteine and methionine metabolism
sjo00480
Glutathione metabolism
sjo01100
Metabolic pathways
sjo01240
Biosynthesis of cofactors
sjo04216
Ferroptosis
Module
sjo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
sjo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
128372984 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
128372984 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
128372984 (gclc)
Enzymes [BR:
sjo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
128372984 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
128372984
NCBI-ProteinID:
XP_053189172
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Position
14:complement(19738794..19750214)
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AA seq
630 aa
AA seq
DB search
MGLLSQGSPLNWDETKKYADHIRKHGIIQFLNIYNKVKDRQKDVLKWGDEVEYMLVELDD
KNEKVRIVLNGGDVLETLQDQGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMGKRRREASLVLNQNETLCTITAFPRLGCPGFTKPEHPPTPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVAINVPIFKDKCTLSPFVEEFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTQEERGLKPLKNNKYRIFKSRYDSIDSYLSSCGEKYNDIDLTIDEEIKKQLL
GGGIDNLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKEAQKRNAV
QEGMFYFRKDIFKGCNPVLDGAASAQNGLETDGTNEEYTLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGDLMTMAKWMREFVAKHPEYKQDSVITDKI
NYDLFVKCDRIAKGEEQCPELIGNPVNRFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactgtcacaggggtctccactgaactgggatgaaaccaagaagtatgcagac
cacatcaggaaacacggaatcatccagtttcttaacatctacaacaaggtgaaggatcgt
cagaaggacgtgttgaaatggggcgatgaggttgagtacatgttagtggaactggatgac
aaaaatgaaaaggttcgaattgtcctgaatggaggagatgttctggaaactcttcaagac
caaggagaaaagataaaccccaatcaccctacgctctggagaccagagtatggcagctac
atgattgaaggaactccagggcagccgtacggcggcacgatgtcagagttcaacactgtc
gagggaaacatggggaagagaagacgagaggcctcattagtcctgaaccagaatgaaacg
ctctgcaccatcactgcattcccaaggttaggttgcccaggtttcaccaaaccagagcac
ccgccaacacctgtagagaagggagtgtcaaagtcgctgttctttccagatgaagccatc
aacagacacccaagattcagcacccttaccagaaacatacgtcacagaagaggagagaaa
gtcgcaattaatgtgccaatcttcaaagacaagtgcactctgtctccatttgtggaggag
tttcctgaggacgatggcgaagcagcgagagcggctctgcctgaccacatctatatggat
gccatgggcttcggcatgggcaactgctgcctgcaggtgacattccaagcatgcagtatt
gatgaagcgcgctacctttatgaccagctagcgacattctgccctatagtgatggctttg
agtgcagcctcgcccttctacagaggctatgtgtcagatattgattgtcgctggggagtt
atttctgcctcagtggacgacagaacacaagaggaacgcgggctgaagcctctgaaaaac
aacaagtacagaatcttcaagtccagatacgattcaattgacagctacctgtccagctgc
ggtgagaagtacaacgacatcgatttgacgatagatgaggagatcaagaagcagctgctt
ggtggaggaattgacaatctgctggcccagcacatagctcacctcttcatccgagatcca
ctctccgtcttcgaggagaaaatacacctggatgatgaaaatgagtctgatcactttgag
aacctccagtcgaccaactggcagacgatgaggtttaaaccaccgcctccaaactctgat
atcggctggagagttgagttccgccccatggaggtgcagctaaccgattttgaaaatgct
gcatacgtggtgtttgtcgtcctgctcaccagagtgatcctgtcctacaaactggatttc
ctaatccccctgtcaaaggttgatgaaaacatgaaggaggcacagaagagaaacgctgtc
caagagggcatgttttacttccggaaggacatctttaaaggctgtaacccggttctcgat
ggtgctgcttcagctcagaatggcctggagactgatggaactaatgaggagtacacactg
atgagcatcgacaccatcatcaatggaaaggagggagtttttcaagggcttatcccaatc
cttaactgctacctggagaacatggaagtcgatgtggacaccagatgcaccatcttgaat
tatctgaagctcatcaagaaacgtgcttcaggggacctgatgaccatggccaagtggatg
agagaatttgtcgcaaagcaccccgagtacaagcaggacagcgtcataaccgacaagatc
aactacgacctgtttgtcaagtgcgacaggatcgcaaagggtgaagagcagtgcccggag
ctcatcggaaacccagtgaacagattcaaatga
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